2022 NFL season predictions for the team with the best regular-season record: Brady and the Buccaneers are back

Tampa Bay Buccaneers quarterback Tom Brady (12) reacts during the first half against the Los Angeles Rams in a NFC Divisional playoff football game at Raymond James Stadium.
Photo of Keith

Keith

NFL · 2 weeks ago

Show Bio

A Bostonian with a love for stats and baseball. Using knowledge and passion to find the right bet in MLB, NBA, NFL, and more. A lover of bold sports takes and sweat free plus odds picks.

September 8 is starting to not seem so far away anymore. The 2022 NFL season is slowly approaching and that means it’s time to start analyzing futures bets and even some season-long prop bets. An exciting prop bet is predicting which team will have the best regular-season record, as all you need to do is root for them to win. Of the 32 teams, usually only about 6 of the squads have a realistic chance to post the best record, so your chances of picking the right team for this prop bet obviously isn’t really 1-in-32.

With that being said, let’s dive into my best bet and my best longshot bet for which team will have the best regular-season record in the 2022 NFL season.

2022 NFL best regular-season record odds

Odds provided by DraftKings Sportsbook

Buffalo Bills (+450)
Tampa Bay Buccaneers (+500)
Green Bay Packers (+650)
Los Angeles Rams (+750)
Los Angeles Chargers (+800)
Kansas City Chiefs (+800)
San Francisco 49ers (+1600)
Dallas Cowboys (+1600)
Indianapolis Colts (+1600)
Denver Broncos (+1600)
Baltimore Ravens (+1600)
Cleveland Browns (+1600)
Philadelphia Eagles (+1800)
Cincinnati Bengals (+2000)

Read our best bets and analysis for the Super Bowl

2022 NFL best regular-season record best bet: Tampa Bay Buccaneers (+500)

Tom Brady continues to age like fine wine. The 44-year-old threw for 5,316 yards, 43 touchdowns and had a 67.5% completion rate in 2021 as the Bucs once again advanced to the playoffs. Besides having arguably the best player of all time as quarterback, the Buccaneers play in the NFC South — which is expected to be terrible in 2022. The Panthers, Saints and Falcons all made major changes at quarterback as Brady will compete against Baker Mayfield, Jameis Winston and Marcus Mariota. That means Brady and company will face those three quarterbacks a total of six times, and I would be surprised if the Buccaneers were anything worse than 5-1 in those games.

Outside of their division, Tampa Bay will play against the Seahawks, Steelers, Browns, Cardinals and 49ers, among a few other teams. Between those five teams mentioned, the Buccaneers are more than capable of winning 3 of those games, at minimum. The Seahawks and Steelers will offer little resistance this season, the Browns still don’t know if Deshaun Watson will be allowed to play, and I believe the Cardinals and 49ers won’t be as strong as most anticipate them to be.

The majority of the Buccaneers’ core is returning in 2022, but they also added some big names. The biggest of all was Julio Jones, who was announced to be joining the team in late July. Other notable additions include DE Shaq Mason, WR Russell Gage, DT Akiem Hicks, DB Logan Ryan and TE Kyle Rudolph — which are detailed in our NFL free agent and offseason moves tracker. Who knows, this might finally be Brady’s finale so I expect a big season for him and the Buccaneers.

Check out our advice for the AFC Championship and NFC Championship

2022 NFL best regular-season record best longshot bet: Philadelphia Eagles (+1800)

The Eagles could be the team that surprises everyone this season. Jalen Hurts demonstrated his potential in 2021, and although he had his flaws, I expect him to be much better this year. Hurts made a connection with DeVonta Smith last season and their chemistry only grew as the season went on, but the Philadelphia front office knew they needed more. They traded for A.J. Brown, who will be an excellent addition down the field for Hurts. Brown rounds out an incredibly dynamic Eagles offense, as Hurts has two speedy receivers downfield and can also use his legs and scramble himself.

It also helps that Philadelphia’s strength of schedule was ranked one of the easiest in football in 2022. They will play the Giants, Commanders and Cowboys twice, and I expect the Eagles to win 4 or 5 of those games. In addition to their division, they play the Lions, Jaguars, Steelers, Texans, Bears and more. That should be 5 wins if the Eagles don’t choke, so that’s already 9-10 wins in about 11 games. With a few big wins against the tougher teams, the Eagles are primed to have a great season with a lot of victories. 

What are the odds on any NFL team going 17-0 this season?

The last team that had an undefeated season was the New England Patriots in 2007. Tom Brady led New England to an 18-0 record before losing to the New York Giants in the Super Bowl. Prior to the Patriots, it was the Miami Dolphins who completed the last perfect season, capped off by winning the Super Bowl that year. If you believe a team will go 17-0 in the regular season, it could be worth the bet on DraftKings at +1400. The Bills and Buccaneers are tied as favorites to go 17-0 at +3500 odds, while most other teams’ odds can be found in the +10000 range.

If you’re so confident in a team to go 17-0 AND win the Super Bowl, you can find that bet at +4000 odds at DraftKings Sportsbook. But remember, no team has done that since 1972, and the game has changed a lot since then. From a value standpoint, it’s not worth the bet on any team this year in my opinion.

Could this +7500 bet on Defensive Player of the Year have value?

Pickswise is the home of free expert NFL Picks and NFL Odds. Be sure to check out all of our season previews and NFL Futures Bets leading up to the 2022 NFL season.

Virginia Bonuses

See All
PointsBet

$500

Get 5x $100 Risk-Free Bets!

Sign up for a new PointsBet account

Make a bet of up to $100 and receive a refund if you lose

Get this offer once a day for the first 5 days you sign up

Must be 21+. Full terms are available at PointsBet.

BetMGM

$200

Get $200 in Free Bets & a PICKSWISE HAT!

Sign up for a new account with BetMGM, and make a deposit of $10+.

Place a $10 moneyline wager on any team

Win $200 in free bets and a FREE Pickswise hat

21+ and new players only. Full terms available at BetMGM Sportsbook.

FanDuel Sportsbook

$250

Bet One, Get One: FanDuel will match your first bet placed up to $250 in free bets

Sign up for a new account with FanDuel Sportsbook

Deposit at least $10 into your account

FanDuel will match your first bet up to $250 in Free Bets!

Must be 21+ in CO. First deposit of at least $10 required. Bonus issued as non-withdrawable free bets that expire 14 days after receipt. See full terms at fanduel.com/sportsbook.

DraftKings

$100

Bet $5+ on MLB and get $100 in Free Bets Instantly!

Sign up for a new account with DraftKings Sportsbook and make your first deposit

Bet $5+ on any MLB team to win their next game

Win $100 no matter what!

Offer valid for new players only. Must be 21 years or older to play. Reward paid in site credit. Full terms available at DraftKings Sportsbook.

PointsBet

$2,000

Get $2,000 in Risk-Free Bets!

Register for a new PointsBet account & deposit

Receive a free bet refund up to $500 if your first fixed odds bet loses

& a free bet refund up to $1,500 if your first two PointsBetting Wager loses

Must be 21+. Full terms are available at PointsBet.

Caesars Sportsbook

$1,500

Get up to $1,500 Risk-Free First Bet!

Sign up for a new Caesars Sportsbook account

Make your first deposit of $50+

If your first bet is not a winner, get it all back as a free bet (up to $1,100) if you lose!

21+. Terms and conditions apply.

Monkey Knife Fight

$100

Claim Instant Deposit Match up to $100 + Free $5 game

Register for a Monkey Knife Fight account & deposit using promo code PICKSWISE100

Monkey Knife Fight will match your first deposit up to $100

Deposit $100 and you'll get $100 bonus + a free $5 game

18+. Terms and conditions apply. You must live in one of the states where real money DFS is legal.

BetRivers

$250

Get a $250 Deposit Bonus!

Sign up for a new BetRivers account using promo code PICKSWISE

Make a deposit & get it doubled up to $250 total

To get a $100 bonus, deposit $100

Must be 21+. Play in IA Only. Gambling Problem? Call 1-800-BETS OFF

Unibet

$500

Get a $500 Risk-Free Bet!

Register for a new Unibet account & make a deposit

Place your first bet up to $500 risk-free!

Get refunded up if you lose up to $500

New players only. Terms & conditions apply. 21+. VA only.

BetMGM

$1,000

Get a $1,000 Risk Free Bet!

Register for a new BetMGM & deposit

Place your first bet up to $1,000 risk-free!

Get refunded up if you lose up to $1,000

21+. Terms & conditions apply.

FanDuel Sportsbook

$1,000

Get a $1,000 Risk Free Bet!

Register for a new FanDuel Sportsbook account & deposit

Place your first bet up to $1,000 risk-free!

Get refunded up if you lose up to $1,000

21+. Terms & conditions apply.

DraftKings

$1,000

Get a $1,000 Deposit Bonus!

Register for a new DraftKings Sportsbook account & deposit

DraftKings will match 20% of your deposit up to $1,000 total

To get a $100 bonus, deposit $500

21+. Terms & conditions apply.

Monkey Knife Fight

$100

Claim 100% Instant Deposit Match up to $100!

Register for a Monkey Knife Fight account & deposit using promo code PICKSWISE100

Monkey Knife Fight will match your first deposit up to $100

Deposit $100 and you'll get $100 bonus + a free $5 game

18+. Terms and conditions apply. You must live in one of the states where real money DFS is legal.

Yahoo DFS

$25

Get $25 in Site Credit With Yahoo DFS When You Deposit $5!

Register for a new account with Yahoo DFS and deposit $5+

Enter a $5 DFS contest

Upon entry, you will receive a bonus $25 in credit into your account!

21+ and new players only. Full terms available from Yahoo DFS.

TVG

$200

Get Your First Single-Horse Win Wager Back Up to $200 if you don't win

Register for a new TVG account and make a deposit

Place your first single horse win-type bet up to $200

If your horse doesn't win you'll get a refund up to $300

21+. T&C's apply. Please gamble responsibly.

TwinSpires

$200

Get a $200 Sign-Up Bonus with Twinspires Racebook!

Open your TwinSpires.com account using offer code BET200

$200 bonus cash will be credited in increments of $100 for every $400 wagered

To earn the full $200 bonus players must wager $800 within 30 days

21+. Terms and conditions apply.