TNF NFL Betting Guide: Expert Detroit Lions vs Green Bay Packers picks, predictions, odds & best bets

Detroit Lions wide receiver Amon-Ra St. Brown (14) celebrates his game winning touch down against the Minnesota Vikings with zero time on the clock during the second half at Ford Field.
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Caleb Wilfinger


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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email

The Detroit Lions already went on the road and pulled off a 21-20 upset of the Chiefs in Week 1 on Thursday Night Football, so what will they do for an encore on Thursday night this week? This week’s TNF game has plenty of potential on paper, featuring a pair of potential playoff teams and division rivals in the Lions and Packers. This could be a massive game in the NFC North division race as the season winds down, so the winner of this game will certainly have the upper hand on paper. 

Here at Pickswise we have everything you need to bet better on Thursday Night Football in Week 4, including NFL picks on the side and total, expert NFL player prop bets from our props betting expert Prop Holliday and also a Same Game Parlay at +1650 odds!  

Let’s get into our picks for Lions vs Packers.

NFL TNF Lions vs Packers Picks

Lions vs Packers best player prop bets

Lions vs Packers Same Game Parlay

NFL Week 4 Predictions

Want even more NFL picks and predictions? Check out some of our NFL predictions for the Week 4 matchups:

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