US Open Day 7 Best Bets & Predictions: 3 Picks for September 5

Third-round competition at U.S. Open wraps up on Saturday, when the remaining spots in the second week will be handed out. Yes, the business end of the tournament is already approaching. Among those looking to keep their title hopes alive are Alexander Zverev, Taylor Fritz, Coco Gauff, Elena Rybakina and Naomi Osaka. 

Here are the best bets to be made on Day 7 in New York City. Following a 3-0 effort on Day 6, let's keep the momentum rolling!

Flavio Cobolli ML over Alexander Blockx (-110)   

Cobolli and Blockx just squared off at last month’s Cincinnati Masters, where Cobolli got the job done 7-5, 4-6, 7-5. If the world #6 can take care of business in that spot, you have to think he will like his chances on the big stage of a Grand Slam and in a best-of-five situation. After all, Cobolli was the Roland Garros runner-up this spring and has reached the Wimbledon quarterfinals each of the past two seasons. It has been a much different story for Blockx – albeit in the very early stages of his career. The 21-year-old Belgian lost in qualifying at all four majors last season and had won just a single main-draw match at a slam (Roland Garros 2026) prior to this tournament. 

Iva Jovic ML over Alexandra Eala (-118)  

Through two matches, Jovic is dominating the head-to-head series between these two rising stars. It’s not they she won each of the first two; it’s the way in which she did it. Jovic cruised 6-4, 6-2 on the red clay of Roland Garros and 6-2, 6-2 on the grass of Queen's Club. Now she can complete the series sweep on the hard courts of the U.S. Open. It is true that Eala always gets a ton of crowd support, but she won't get quite as much against Jovic on the American's home turf. Although Eala has been in slightly superior form in recent weeks, this is her 13th match of the hard-court summer. That's a lot of wear and tear on the 21-year-old Filipino. By contrast, this is Jovic's eighth match during the same stretch. 

Francisco Cerundolo Under 16.5 games won vs Taylor Fritz (-110)  

This sets up extremely well for total domination by Fritz. The 10th-ranked American has home-court advantage at an event in which he made a run all the way to the final in 2024. Cerundolo, by contrast, has never done much of anything at Flushing Meadows. In fact, the Argentine’s hard-court results have underwhelmed just about everywhere throughout his career other than in Miami. Additionally, Cerundolo is coming off a five-set thriller against Jan-Lennard Struff on Thursday. Fritz, on the other hand, clobbered Darwin Blanch 6-3, 6-2, 6-4 and then made 6-0, 6-1, 6-1 mincemeat out of Mattia Bellucci. The #9 seed is well rested, in stellar form and playing on a surface that favors him to a massive extent.