College Football Week 1 Betting: Odds, Picks & Best Bets

Ladies and gentlemen, welcome to the first PROPER college football Saturday slate of the season! Sure, Week 0 served as a nice little appetizer, but this is where things get real. Week 1 is finally here, and we have an avalanche of awesome matchups to enjoy all day long. Get comfortable on your sofa and buckle up, because Saturdays in 2026 won't be the same again. You can find out all of our college football picks and CFB predictions for the major matchups on Saturday, with 26 games covered. On top of that, we have our college football expert’s best bets of the day, along with our CFB parlays to help you bet better today across all of the NCAAF action. Let’s dive in!

College football Week 1 best bets

• CFB Week 1 best bets - our expert has gone 4-0 with his CFB best bets so far this season! Find out his 3 top plays for Saturday

College football Week 1 parlays

Get set for the first mega Saturday slate of the 2026 CFB season with our expert's best college football parlays:

• College Football Week 1 Parlay - we nailed our Week 0 parlay at +346 odds and cashed another parlay at +591 on Thursday. Now find out our mega parlay picks for Saturday!

College football Week 1 props

• CFB Week 1 player props - check out our expert's three best player prop picks for Week 1
• CFB Week 1 anytime touchdown scorer best bets - bank on these 3 picks to find the end zone, including a longshot pick at big odds!

College football Week 1 picks

Check out our expert college football predictions for the biggest games in Week 1 below:

• North Texas vs Indiana prediction
• East Carolina vs Alabama prediction
• Ohio vs Nebraska prediction
• Miami (Ohio) vs Pitt prediction
• Ball State vs Ohio State prediction
• Texas State vs Texas prediction
• Boise State vs Oregon prediction
• Baylor vs Auburn prediction
• Marshall vs Penn State prediction
• Northern Illinois vs Iowa prediction
• Abilene Christian vs Texas Tech prediction
• Missouri State vs Texas A&M prediction
• Western Michigan vs Michigan prediction
• Clemson vs LSU prediction
• FAU vs Florida prediction
• UNLV vs Hawaii prediction
• UCLA vs Cal prediction
• Washington State vs Washington prediction
• Louisville vs Ole Miss prediction
• Wisconsin vs Notre Dame prediction