Houston Astros vs Boston Red Sox Prediction, Odds and Picks for Today, 05/01/26

The Houston Astros and Boston Red Sox begin a series on Friday night. These have been 2 of the most disappointing teams in baseball so far, and each team has only 12 wins on the season. Both also sit in last place in their division. The Red Sox have already fired a coach, and this week they lost Garrett Crochet to the IL. Tonight would have been his start. For the Astros, the problem has been pitching — as they have the worst team ERA in baseball. So we have a lot going on in this spot tonight, and this is a tough spot for bettors. With trepidation, I am taking the Red Sox to win.

In place of Crochet, the Sox will call up Jake Bennett. Bennett was a second-round pick a couple of years ago and then had Tommy John (as they all do these days). He is a big guy but not necessarily an overpowering arm, but he has several pitches and draws a lot of weak contact. He looks like a mid-rotation pitcher. He will face Mike Burrows, who is probably only starting because the Houston rotation is a MASH unit. The Astros have the better offense, but I will take my chances with the rookie pitcher — knowing that once the Houston bullpen gets involved, everything usually gets silly. Give me the Red Sox.

Astros vs Red Sox prediction: Boston ML (-125) available at time of publishing. Playable to -135.

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