Wise n' Shine: College football picks, MLB predictions and NFL odds for Saturday, September 24

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Phil Agius


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I've been writing about the NFL and a host of other sports for the UK's top daily betting paper the Racing Post for more than 20 years. An incurable Browns fan (1-31 survivor), I also specialise in all kinds of motorsport betting including F1, MotoGP, IndyCar and NASCAR. For Phil Agius media enquiries, please email contact@pickswise.com.
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Welcome to another super Saturday of sports! We have a huge day in Week 4 of the college football season, along with a full MLB slate and MLS soccer, so let’s get straight to making your next bet better!

About Last Night

Amazing day of baseball picks!
The Pickswise team went a phenomenal 13-2 on Friday’s ML/RL picks and 9-5-1 on totals, also cashing our only 3-star play on Mets -1.5 as they crushed the A’s 9-2. Our best MLB prop bet also hit and our Friday parlay was a +409 winner too! The Phillies beat the Braves 9-1, the Yankees got the better of the Red Sox 5-4, the Orioles shut out the Astros 6-0 and the Cardinals ended the night with an 11-0 win over the Dodgers.

NCAAF mega parlay cashes
We have started college football Week 4 in fine form, cashing our standard parlay at +596 odds on Thursday and then hitting our Friday mega parlay at +618 odds! Syracuse almost blew a 16-point halftime lead in a 22-20 win over Virginia, but moved to 4-0 on the season.

Today’s Slate

Huge slate of college football
Today has everything the college football fan could want with a huge slate of games, starting with Kent State vs Georgia at noon on ESPN+. Florida faces Tennessee on CBS at 3:30 pm ET and Arkansas vs Texas A&M is on ESPN at 7:00pm ET. Check out today’s NCAAF picks.

15 MLB games today
We have a full MLB Saturday slate, with the Red Sox and Yankees getting things started at 1:05pm ET and Tigers vs White Sox being shown on ESPN+ at 7:10pm ET. Read today’s MLB predictions.

MLS action
There’s no EPL action this weekend due to international games but there is one MLS game and we have soccer picks for Galaxy vs Earthquakes at 10:00pm ET on ESPN+.

NFL odds and news

The big NFL injury news heading into Sunday’s Week 4 slate is that Chargers QB Justin Herbert is questionable to play against the Jaguars after missing Friday practice with his broken rib cartilage. The Chargers have dropped from 10.5-point favorites for the game to as little as -3 with some sportsbooks. Chase Daniel will start if Herbert is unable to go.

Best Bet of the Day

CFB: Michigan Wolverines -17 over Maryland Terrapins
12:00 pm ET, BTN

Michigan has the #1 scoring offense in the country and the #4 scoring defense while allowing just 91 passing yards per game to opponents. This takes into account that their three opponents so far have been Colorado State, Hawaii and UConn, but that doesn’t change how good this defense is. The Wolverines welcome the Maryland Terrapins this week for their first Big Ten conference game of the year. The Terrapins have been been averaging 40 points per game this year but could falter on defense. They gave up 21 points to Charlotte and 27 to SMU. The Terps won just two road games last year and one in each of 2020 and 2019. Furthermore, their prolific offense was all but shut down by the Big Ten’s best defenses. Read our full Maryland vs Michigan predictions.


Don’t forget to check out our daily show Let’s Bet It on our YouTube channel at youtube.com/c/Pickswise at 10:00 am ET.

David Gascon and Mark Zinno are your hosts today and they will be joined by guest Bryant McFadden (@BMac_SportsTalk), football analyst for CBS Sports and former Pittsburgh Steelers and Florida State cornerback, to look at this week’s key games. The team will also have their best bets for today’s college football and MLB games and give out their Plays of the Day.

You can also access the show at any time through Spotify and Apple Podcasts (search for Let’s Bet It Presented By Pickswise).

The Week 3 edition of Pickwise Playbook, our weekly NFL preview show, is also available, featuring former NFL star Tank Williams, so be sure to check that out too!


Everything you need for today’s college football is contained within our college football Week 4 betting guide, which has the links to all today’s picks, parlays, previews and expert analysis.

There’s a ton of NFL Week 3 content available too, including our experts’ best bets and Week 3 mega parlay, and don’t forget to check out all our NFL game previews, which now include same game parlay picks.

As for today’s baseball, we have today’s YRFI/NRFI best bets and Saturday MLB mega parlay.

Read all of our great sports analysis as it arrives throughout the day on the Analysis tab.

Stat of the Day

Chad Kuhl of the Rockies has a 0-4 record and a 9.00 ERA in 8 starts since the all-star break.

Quote of the Day

“It’s been a perfect journey. I would do it all over again.”

Roger Federer played his final match before retirement in London yesterday.

Pickswise is the home of free sports picks, news and best bets. Check out our expert NFL Picks, NBA Picks, MLB Picks and NHL Picks pages for our latest game picks.

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