NFL Best Bets

Get our experts’ best NFL bets this week and every week of the 2025/26 season. Our experts analyze their NFL picks and predictions across a whole host of markets to give you their best NFL Bets today.

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Point Spread (2)

Experts

Guest Experts (1)Pickswise Experts (1)

1:00 PM ET

Sun Jan 4

Saints

Falcons

Point Spread PickBest Bet

NO Saints +3.5(-115)

Reasoning

Both New Orleans and Atlanta have played well down the stretch although each of these NFC South rivals are eliminated from playoff contention. The Saints (6-10) are riding a 4-game winning streak, coming off a 34-26 victory at Tennessee. New Orleans grabbed its 3rd victory in the last 4 tries away from the Superdome after starting 0-4 on the road. The Falcons (7-9) have avoided its 10th loss for 3 consecutive weeks, beating the Buccaneers, Cardinals, and Rams. Atlanta jumped out to a 21-0 lead over Los Angeles before holding on for a 27-24 triumph on Monday night as 7-point underdogs.

In the first matchup in New Orleans back in Week 12, the Falcons took care of the Saints, 24-10 as 2-point underdogs. Veteran Kirk Cousins made his first start of the season in place of the injured Michael Penix, Jr., throwing for 199 yards and a pair of scores. The Saints couldn’t get any offense going with their lone TD coming on an interception return. New Orleans missed a pair of field goals and turned the ball over twice, as the Falcons seek back-to-back wins over the Saints for the first time since 2016-2017.

Atlanta has struggled in its last two opportunities as a home favorite, losing to Miami (34-10) and Carolina (30-27). The Saints began the season with a 3-8 ATS record, but stormed back with 5 consecutive covers. Shough has put together back-to-back 300+ yard performances against the Jets and Titans, but posted a 74.1 passer rating in the first matchup with Atlanta. Both teams want to finish the season with a nice winning streak going into the offseason, but let’s back the Saints with the points here to capture their sixth straight cover.

Saints vs Falcons prediction: Saints +3.5 available at time of publishing. Playable to +3.

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Kevin Rogers

4:25 PM ET

Sun Jan 4

Chiefs

Raiders

Point Spread PickBest Bet

KC Chiefs -5.5(-110)

Reasoning

The 2025 NFL season will come to an end for the Kansas City Chiefs and Las Vegas Raiders when these 2 AFC West foes clash in Week 18 on Sunday afternoon. Neither team is going to the playoffs — not even close. Even against a team playing as poorly as Kansas City is right now, Las Vegas is pretty much an automatic fade. When the Raiders are getting less than a touchdown, it’s a can’t–miss opportunity — regardless of the opponent. My Chiefs vs Raiders pick is for the visitors to win and cover. Las Vegas was awful even when it was trying to win games earlier in the season. Now head coach Pete Carroll’s club is making no secret about its disinterest — and perhaps even its desire to lose. In Week 17, the Raiders faced the Giants in what was a battle for a stranglehold on the #1 pick in the 2026 draft. Having already shut down their 2 best players — defensive end Maxx Crosby and tight end Brock Bowers — for the season, Las Vegas unsurprisingly got clobbered by New York 34-10. That’s right; the Raiders lost to the other worst team in football by 24 points.

Kansas City may be wrapping up a horrendous season, but at least you can count on it playing hard through the finish line. The Chiefs lost to the Broncos by only 7 points on Christmas in a game that was competitive from start to finish. Their offense is obviously a problem with Patrick Mahomes sidelined, but it doesn’t have to be very good to comfortably beat Las Vegas. Moreover, head coach Andy Reid’s squad is essentially playing on a mini-bye. Give Reid extra preparation time — even for a meaningless game — and good things usually happen. I’m backing K.C. with confidence.

Kansas City Chiefs vs Las Vegas Raiders prediction: Chiefs -5.5 (-110) available at time of publishing. Playable to -6.

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Ricky Dimon

NFL Best Bets

49.3%

Win %

33Wins

34Losses

1Pushes

Percentage only includes Wins and Losses

At Pickswise our experts put in countless hours of research and analysis every week to bring you free NFL best bets. Although the NFL regular season is just 18 weeks long, there are still 272 regular-season NFL games to decipher, as well as the NFL playoffs, so we bring you free NFL best bets this week and across the whole season and post-season.

Best NFL Bets Today

The NFL action comes thick and fast during the season and we cover all of it. Our NFL Best Bets should be your first port of call here at Pickswise alongside the NFL Picks page where you can find the entire catalog of our weekly game previews which combine for a comprehensive view of all of today’s NFL games and best bets. Check back every week for those Monday Night, Thursday Night and Sunday slates’ best NFL picks, all for free.

Best NFL Bets This Week

The NFL is very much a look-ahead sport, particularly within sports betting. Almost as soon as the previous week’s games are done, oddsmakers and bettors alike are already trying to find the best bets for NFL this week. Here at Pickswise, we’re no different.

You can often find great value early in the week and our experts will take an early look ahead, so we get our best bets for NFL this week posted on-site as soon as possible, so you can lock in those best lines and odds before the inevitable movement later in the week. Be sure to keep an eye on the NFL best bets page every day on game week as our experts continue to highlight those biggest edges and best NFL bets.

What Is An NFL Best Bet at Pickswise?

Our expert NFL cappers post their best bets on this week’s NFL games across a whole host of betting markets. Each of our selections on Pickswise is given a confidence rating ranging from 1 to 3 stars, with 3 stars being the most confident, and 1 the least. Our NFL Best Bets page details those 3 star rated bets, making them our expert’s NFL Best Bets on this week’s games.

How We Decide Our Best NFL Bets at Pickswise

Each week of the NFL season, as our experts deep-dive into the stats and make their picks and predictions for the week’s coming games each expert handicapper gives their reasoning and the data to back up their selections. Through a robust process of debate and consideration, taking into account the odds, potential winnings and an expert judgement on the bet’s outcome, they come to a consensus on the confidence rating for each play. Only those that get a 3 star confidence rating through this process qualify as an NFL best bet.

All our handicappers vie for their picks to get the NFL best bet stamp, each and every week of the season. It’s this friendly competition amongst experts that ensures are NFL best bets are indeed the best NFL bets you’ll find anywhere.

Where Should I Bet On Your NFL Best Bets Today

Another important strategy for maximizing your NFL betting success is to make sure you have access to the best odds and lines available across all of the best online sportsbooks.

Alongside our NFL best bets, we also highlight the best odds and lines that the sportsbooks are currently offering. This ensures you’re maximizing your chances of turning a profit over time as every half point or fractional odds difference adds up over the season.

For more on our recommended NFL sportsbooks, check out our rankings for the best NFL betting sites. The best odds, a diverse range of NFL betting markets and an overall user-friendly app experience are just some of the key factors we consider.

Unsure where is best to place your online sports wagers? Or looking to make the most of new player bonuses and promo codes? Be sure to check out our Online Sportsbook Promotions for expert analysis of the best sportsbook welcome offers available in your state.

57 Wins from 2024/25 NFL Best Bets

When Pickswise tells you that we have an NFL Best Bet, we mean it. In the 2024 season, our team of expert NFL handicappers finished with 57 wins on our NFL best bets and we are hungry to provide even more winners this season. We don’t just throw around 3 star plays, all of our cappers and editors meticulously break down each pick and predictions before we put our NFL best bet stamp on it. We often have best bets each week of the season, but tail our expert NFL cappers with confidence this week.

Andrew Wilsher, Pickswise Managing Editor

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NFL Best Bets FAQs

What Is The Best Bet On In The NFL?

There are endless ways in which you can bet on the NFL and the Best Bet is a winning one. The Pickswise Best Bets page is a collation of our expert handicappers’ most confident selections on this week’s NFL games. While we can’t guarantee every bet will win, we have a long-trusted and proven record, our NFL Best Bets returned 57 wins across the 2024/25 season.

What Are The Best Numbers To Bet For NFL?

The most important numbers to consider when betting on the NFL are 3 and 7. A lot of games in the NFL are decided by one score so when you’re looking at spread lines you must keep Field Goals and Touchdowns at the forefront of your mind, as there is a big difference between -3.5 and -2.5 and -6.5 and -7.5.

How Do I Know What The Best NFL Bets Are

At Pickswise we use a star system to show our cappers’ confidence in that particular pick. All of our Best NFL Bets get our top confidence rating of 3 stars.