HomeNFLNFL PredictionsDetroit Lions vs Los Angeles Rams Predictions, Odds & Expert Picks for NFL Week 15 2025

Detroit Lions vs Los Angeles Rams Predictions, Odds & Expert Picks for NFL Week 15 2025 for Sunday, 12/14/25

Updated: 5:37 AM ET Dec 11, 2025

SoFi StadiumFOX

Lions

4:25 PM ETSun Dec 14

Rams

WLWLW	Last 5	WWWLW
8-5	Record	10-3
7-6-0	ATS Record	9-4-0
8-5	O/U Record	6-7

Lions vs Rams Best Bets

Point Spread PickBest Bet

LA Rams -6.0(-110)

Reasoning

The top seed in the NFC is up for grabs heading into the final 4 weeks of the season. The Rams and Seahawks are tied atop the NFC West at 10-3 as the two squads meet next Thursday in Seattle. However, Los Angeles needs to take care of Detroit on Sunday at SoFi Stadium as the Lions are fighting for their playoff lives at 8-5. Detroit has alternated wins and losses in each of the past 9 games, coming off the 44-30 home triumph over Dallas last Thursday.

The Lions finished as the top NFC seed last season at 15-2, but were one-and-done in the playoffs after losing to the Commanders in the divisional round. Detroit hasn’t been able to find consistency since posting a 4-game winning streak following its opening week loss at Green Bay. Dan Campbell’s team is 3-3 away from Ford Field, which includes a 1-3 ATS mark as a road underdog. The Lions are averaging 18.5 ppg in the last 4 games off a victory, compared to 36.3 ppg in their first 3 games off a win.

The Rams bounced back from a shocking loss at Carolina 2 weeks ago to rout the banged-up Cardinals, 45-17 as 9.5-point road favorites. QB Matthew Stafford rebounded from a rough performance against the Panthers by throwing 3 TD passes and no interceptions. The Rams are back at SoFi Stadium, where they own a 5-1 record with the lone loss coming in overtime to the 49ers in Week 5. Los Angeles hopes to avenge a pair of defeats at Detroit the last 2 seasons, including in the 2023 Wild Card round, 24-23. Seeing Detroit’s inconsistency the last 2 months, let’s lay the points with the Rams here to take care of business at home.

Lions vs Rams best bet: Las Angeles Rams -6 (-110) available at time of publishing. Playable to 6.5.

If you’re looking for a new sportsbook, check out Bet365, the world’s #1 sportsbook. They have an amazing sign-up offer where you can INSTANTLY receive $150 in bonus bets from a $5 wager, regardless of whether that bet wins or loses! There’s no catch, it’s really that simple. Join Bet365 right now ⏰ in time to fade or follow our experts’ Lions vs Rams predictions.

Lions vs Rams Pickswise Expert Predictions

Game Totals Pick

Under 55.0(-110)

Reasoning

The Lions rank 1st in the league in scoring at 30.3 ppg, while the Rams sit 4th at 29.2 ppg, so the expectation is this will be an up-and-down affair in Los Angeles. However, the Rams are 6-6-1 to the over, while the Lions are 8-5 to the over. L.A. went through a 4-1-1 run to the under from mid-October through late November before cashing in a pair of overs the last 2 weeks. The Rams scored 28 points in a loss at Carolina before racking up a season-high 45 points in last Sunday’s rout of Arizona.

The Lions bounced back from a Thanksgiving Day loss to Green Bay by putting up 44 points on Dallas last Thursday. Detroit posted at least 44 points for the 3rd time this season, along with a 44-point output at Washington and a 52-point barrage against Chicago in Week 2. In 2 of the past 3 road games, the Lions have been limited to 17 or fewer points, including a season-low 9 points at Philadelphia in Week 11.

Each of the last 2 matchups between the Rams and Lions have seen the under cash. Detroit edged L.A. in the 2023 Wild Card round 24-23 on a 53 total, while the Lions knocked off the Rams in overtime early last season 26-20 on a 53.5 total. Sunday’s total at SoFi Stadium is up to 55, which is the highest of the season for the Rams. Detroit is 3-2 to the over on totals above 50, while going 1-1 to the over on the road. The Rams are 4-1-1 to the under at home as the lone over against San Francisco would have remained under if not for a last-second game-tying field goal to force overtime.

This feels like a heavy total even though these teams have the capability to go score plenty of points. In this battle of 2 former top picks facing their old teams in Matthew Stafford and Jared Goff, let’s look at the under in this much anticipated battle in southern California.

Lions vs Rams pick: Under 55 (-110) available at time of publishing. Playable to 54.5.

You can bet on our Lions vs Rams pick with BetMGM, where right now new users can activate your new BetMGM account ⚡ and receive $150 in bonus bets INSTANTLY if your first $10+ wager is a winner!

Show Bio

Kevin covers the NFL for Pickswise from sunny south Florida. He has been handicapping the NFL professionally since 2007, as well the NBA, MLB, NHL, college football, and college basketball. He looks forward to a profitable season at Pickswise.

@RogersPicks

No Sweat First Bet Up to $2500 back in Bonus Bets

Make a minimum deposit of $500

Place your first bet and if it loses, you'll get your money back in Bonus Bets, up to $2,500

Gambling Problem? Call 1-800-GAMBLER. Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ and present in select states. FanDuel is offering online sports wagering in Kansas under an agreement with Kansas Star Casino, LLC. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, KY, MI, NJ, OH, PA, IL, TN, VA, VT), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), visit www.mdgamblinghelp.org (MD), 1-800-522-4700 (WY), or visit www.1800gambler.net (WV).

$2,500

No Sweat First Bet Up to $2500 back in Bonus Bets

Make a minimum deposit of $500

Place your first bet and if it loses, you'll get your money back in Bonus Bets, up to $2,500

$2,500

No Sweat First Bet Up to $2,500 back in Bonus Bets

Gambling Problem? Call 1-800-GAMBLER or call 1-877-8HOPE-NY or Text HOPENY (467369 (NY) JOINNOW 21+ in select states. First online real money wager. $10 deposit required. Refund issued as non-refundable bonus bets that expire in 14 days. Restrictions apply. See full terms at fanduel.com/sportsbook. FanDuel is offering online sports wagering in Kansas under an agreement with Kansas Star Casino, LLC. Gambling problem call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MI, NJ, OH, PA, IL, TN, VA). 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS). 1-877-770-STOP (LA). visit www.mdgamblinghelp.org (MD). 1-877-8-HOPENY or text HOPENY (467369). 1-800-522-4700 (WY). or visit vwww.1800gambler.net (WV)

40 Sweeps Coins

80,000 Gold Coins, 40 Free Sweeps Coins + 100 Free Spins on First Purchase

Make a $19.99 purchase and you'll get 100 Free Spins

Plus, you'll get 80,000 Gold Coins + 40 FREE Sweeps Coins

No Purchase Necessary. 21+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

40 Sweeps Coins

80,000 Gold Coins, 40 Free Sweeps Coins + 100 Free Spins on First Purchase

Make a $19.99 purchase and you'll get 100 Free Spins

Plus, you'll get 80,000 Gold Coins + 40 FREE Sweeps Coins

No Purchase Necessary. 21+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

40 Sweeps Coins

80,000 Gold Coins, 40 Free Sweeps Coins + 100 Free Spins on First Purchase

Make a $19.99 purchase and you'll get 100 Free Spins

Plus, you'll get 80,000 Gold Coins + 40 FREE Sweeps Coins

No Purchase Necessary. 21+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

$200

Spend $100, Get $200 in Fliff Coins

Download the Fliff Sportsbook app and sign up for an account

Spend $100 on any wagers

You'll get $200 back in Fliff Coins

Promotional offer only valid for new users that are 18+ years old. Purchase of Fliff Coins is not required to participate in sweepstakes. In-app purchases do not increase a player\\\'s odds of winning sweepstakes. Fliff Cash credits will only be given to users with less than $5 available in Fliff Cash in their account. Fliff Coins are not eligible for cash withdrawals.

Bonus

Play Now on Underdog

Must be 18+ (19+ in AL, NE; 19+ in CO for some games; 21+ in AZ, MA, and VA) and present in a state where Underdog Fantasy operates. Terms apply. See assets.underdogfantasy.com/web/PlayandGetTerms_DFS_.html for details. Offer not valid in MD, MI,NY, OH, and PA. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Bonus

Play Now on Underdog

Bonus

Play Now on Underdog

280 Coins

Mega Boost: Up to 280 Free Sweep Coins + 2.8M Gold Coins on First Purchase

No Purchase Necessary. 18+

Void where prohibited by law.

See Terms of Service/Terms of Conditions/Terms of Use.

No Purchase Necessary. 18+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

280 Coins

Mega Boost: Up to 280 Free Sweep Coins + 2.8M Gold Coins on First Purchase

No Purchase Necessary. 18+

Void where prohibited by law.

See Terms of Service/Terms of Conditions/Terms of Use.\"

No Purchase Necessary. 18+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

NFL Analysis

See All NFL News

Atlanta, Georgia, USA; Atlanta Falcons linebacker Arnold Ebiketie (17) and safety Jessie Bates III (3) tackle Tampa Bay Buccaneers quarterback Baker Mayfield (6) during the fourth quarter at Mercedes-Benz Stadium.

Thursday Night Football Predictions: Atlanta Falcons vs Tampa Bay Buccaneers Expert Picks, Odds & Best Bets for Week 15

Thursday Night Football gets NFL Week 15 started and it begins with a crunch clash in the NFC South, as the Tampa Bay Buccaneers host the Atlanta Falcons. The Falcons are in a complete tailspin, losi...

NFLPosted 7 hours ago