1
BetMGM
1
Caesars Sportsbook
1
bet365
1
DraftKings
1
FanDuel Sportsbook
1
PlayBracco
1
Fliff Social Sportsbook
1
High 5 Casino
1
Sportzino
1
Pulsz
1
WOW Vegas
1
McLuck
1
Hello Millions
Detroit Lions

Detroit Lions vs Philadelphia Eagles Predictions, Odds & Expert Picks for Sunday Night Football Week 11 2025 for Today, 11/16/25

Lincoln Financial FieldNBC
Lions
Lions
Today
Eagles
Eagles
WLWLW
Last 5
LLWWW
6-3Record7-2
6-3-0ATS Record6-3-0
5-4O/U Record5-4
Philadelphia Eagles

Lions vs Eagles Pickswise Expert Predictions

Point Spread Pick
PHI Eagles -2.0(-115)

It wasn’t a pretty game, but the Eagles survived Lambeau Field and came out the victors in a big time NFC battle this past Monday night. It doesn’t get any easier for the Super Bowl champions as they travel back home to face the Detroit Lions, who looked as explosive and potent ever under Dan Campbell’s direction as their new play-caller. In an absolute thrashing, the Lions gained 546 yards on eight yards per play and dropped 44 points on the Commanders while the 47th president of the United States was in attendance. It was a display of how great Detroit can be when all is in-sync, especially off a loss. Dan Campbell’s incomparable record of 13-0 against the spread following a straight up loss earned another stripe this past Sunday.

Of course, while the Philadelphia offense left much to be desired, their defense looked better than it had all season in Week 10. Against a Packers offense that is as talented as any in the NFL, Philly held Green Bay to just 261 total yards and four yards per pass. New addition Jaelan Phillips contributed four solo tackles and six defensive stops, already becoming a crucial part of their operation. The Eagles also sacked Jordan Love 3 times and left him lost on most plays, scrambling to find an open receiver against the Eagles’ top-tier secondary. Philly also held Josh Jacobs to just 74 yards on the ground.

Returning home to the warm embrace of a raucous Philadelphia crowd, the Eagles have a better spot since the Lions are now on their second straight road game in 13 days. Amazingly, although both have been at the top of the NFC conference for a few years now, the Eagles and Lions haven’t collided since 2022, so there’s not much we can glean from the previous battle. What we can say is that, while Campbell’s new play calling role is interesting and the Lions are always a formidable threat, this Sunday night isn’t the same situation. The Eagles are healthy and look as focused as they ever have, while the Lions’ secondary just got another dose of the injury bug last weekend (Terrion Arnold left with a concussion). We’re siding with the champs in what should be a highly entertaining contest.

Lions vs Eagles prediction: Eagles -2 (-115) available at time of publishing. Playable to 2.5.

You can bet on our Lions vs Eagles pick with BetMGM, where right now new users can activate your new BetMGM account ⚡ and receive $150 in bonus bets INSTANTLY if your first $10+ wager is a winner!

BET -2.5 NOW WITH
Fanatics Sportsbook$2,000
JOIN NOW
bet365$200
JOIN NOW
BetMGM$1500
JOIN NOW
Caesars Sportsbook$200
JOIN NOW
DraftKings$300
JOIN NOW
FanDuel Sportsbook$150
JOIN NOW
Sleeper$20
JOIN NOW
UnderdogBonus
JOIN NOW
Dabble Fantasy$25
JOIN NOW
Parlay Play$100
JOIN NOW
betr$200
JOIN NOW
PlayBracco750
JOIN NOW
Chris R. Farley
Game Totals Pick
Over 46.5(-110)

Despite a terribly low total last week in Philadelphia’s battle (a 10-7 finish), this number is still fairly high. In a one game Week 10 sample size, the Lions and Eagles offenses look like two completely different operations, one firing on all cylinders and nearly hitting 600 total yards, while the other barely got by on just 4.9 yards per play. It’s the Lions’ defense that alters projections. Detroit has several strengths defensively, particularly in all-pro Aidan Hutchinson, who leads a front-seven that averages a sack on 9.52% of plays (4th). In the more macro numbers, Detroit has plenty of issues. They allow seven yards per pass (17th) and when opponents are in the red zone they typically buckle, permitting a touchdown on 2/3 of enemy drives (25th).

The Eagles’ offense didn’t do much in Week 10, but it didn’t have to. We also don’t think their defense won’t be quite as successful in this affair, either. When change is good it tends to catalyze performance, and it’s not like the Lions’offense hasn’t been extremely prolific anyway. Detroit ranks top-five or better in more than a few important categories, including points per game (2nd), explosive plays (2nd), completion percentage (1st) and yards per pass (5th). The Eagles have an edge in this game because of their defense, but that doesn’t mean this will be a low-scoring game.

Lions vs Eagles pick: Over 46.5 (-110) available at time of publishing. Playable to 47.5.

Bet like a Caesar with this AMAZING new customer offer from Caesars Sportsbook. If you bet just $1, you’ll receive DOUBLE YOUR WINNINGS on your next 20 bets! Become a Caesars member 👥 using the Caesars promo code PWCONTENT20X, where you can bet on our Lions vs Eagles picks.

BET o46.5 NOW WITH
Fanatics Sportsbook$2,000
JOIN NOW
bet365$200
JOIN NOW
BetMGM$1500
JOIN NOW
Caesars Sportsbook$200
JOIN NOW
DraftKings$300
JOIN NOW
FanDuel Sportsbook$150
JOIN NOW
Sleeper$20
JOIN NOW
UnderdogBonus
JOIN NOW
Dabble Fantasy$25
JOIN NOW
Parlay Play$100
JOIN NOW
betr$200
JOIN NOW
PlayBracco750
JOIN NOW
Chris R. Farley
Photo of Chris Farley

Chris Farley

Chris is a writer for Pickswise who’s been handicapping the NFL since 2011. He began his public betting career as a betting writer, and has since become a contributing analyst for various betting sites and shows. He was a 5th place winner ($114k) in the 2021 NFL Circa Millions contest, and he owns his own sports betting podcast, Laying the Points. Chris approaches handicapping using psychosocial principles and nuanced market analysis. The NFL and NBA are his favorite and most profitable sports.
@FarleyBets
Read more about Chris Farley

Featured In

Top Trends
Game Totals

The Over is 12-8 in the Eagles' and the Lions' last 10 games combined.

Point Spread

The Eagles have covered in 6 of their 9 games this season.

Money Line

The Eagles have won their last 3 matchups against NFC teams.

PlayBracco

750

50% First Deposit Bonus, up to 750 Bracco Cash

Sign up for a new account on PlayBracco

Make your first deposit

It\\\'ll be matched 50%, up to 750 Bracco Cash!

This promotion is available to new Bracco customers only. Customers must be 18 years of age or older (or the legal age of majority in their jurisdiction) to participate. This offer is limited to one promotion per person, household, IP address, and payment method.

PlayBracco

750

50% First Deposit Bonus, up to 750 Bracco Cash

Sign up for a new account on PlayBracco

Make your first deposit

It\'ll be matched 50%, up to 750 Bracco Cash!

This promotion is available to new Bracco customers only. Customers must be 18 years of age or older (or the legal age of majority in their jurisdiction) to participate. This offer is limited to one promotion per person, household, IP address, and payment method.

PlayBracco

750

50% First Deposit Bonus, up to 750 Bracco Cash

Sign up for a new account on PlayBracco

Make your first deposit

It'll be matched 50%, up to 750 Bracco Cash!

This promotion is available to new Bracco customers only. Customers must be 18 years of age or older (or the legal age of majority in their jurisdiction) to participate. This offer is limited to one promotion per person, household, IP address, and payment method.

Jackpota

60 Sweeps Coins

200% on First Purchase: 120,000 GC + 60 FREE SC

Sign up for a new Jackpota account

Make a $19.99 purchase and you'll get 200% match

Plus, you'll get 120,000 Gold Coins + 60 FREE Sweeps Coins

No Purchase Necessary. 21+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

Jackpota

60 Sweeps Coins

200% on First Purchase: 120,000 GC + 60 FREE SC

Sign up for a new Jackpota account

Make a $19.99 purchase and you'll get 200% match

Plus, you'll get 120,000 Gold Coins + 60 FREE Sweeps Coins

No Purchase Necessary. 21+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

Jackpota

60 Sweeps Coins

200% on First Purchase: 120,000 GC + 60 FREE SC

Sign up for a new Jackpota account

Make a $19.99 purchase and you'll get 200% match

Plus, you'll get 120,000 Gold Coins + 60 FREE Sweeps Coins

No Purchase Necessary. 21+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

Fliff Social Sportsbook

$200

Spend $100, Get $200 in Fliff Coins

Download the Fliff Sportsbook app and sign up for an account

Spend $100 on any wagers

You'll get $200 back in Fliff Coins

Promotional offer only valid for new users that are 18+ years old. Purchase of Fliff Coins is not required to participate in sweepstakes. In-app purchases do not increase a player\\\'s odds of winning sweepstakes. Fliff Cash credits will only be given to users with less than $5 available in Fliff Cash in their account. Fliff Coins are not eligible for cash withdrawals.

Underdog

Bonus

Play Now on Underdog

Must be 18+ (19+ in AL, NE; 19+ in CO for some games; 21+ in AZ, MA, and VA) and present in a state where Underdog Fantasy operates. Terms apply. See assets.underdogfantasy.com/web/PlayandGetTerms_DFS_.html for details. Offer not valid in MD, MI,NY, OH, and PA. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Underdog

Bonus

Play Now on Underdog

Must be 18+ (19+ in AL, NE; 19+ in CO for some games; 21+ in AZ, MA, and VA) and present in a state where Underdog Fantasy operates. Terms apply. See assets.underdogfantasy.com/web/PlayandGetTerms_DFS_.html for details. Offer not valid in MD, MI,NY, OH, and PA. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Underdog

Bonus

Play Now on Underdog

Must be 18+ (19+ in AL, NE; 19+ in CO for some games; 21+ in AZ, MA, and VA) and present in a state where Underdog Fantasy operates. Terms apply. See assets.underdogfantasy.com/web/PlayandGetTerms_DFS_.html for details. Offer not valid in MD, MI,NY, OH, and PA. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Chanced.com

280 Coins

Mega Boost: Up to 280 Free Sweep Coins + 2.8M Gold Coins on First Purchase

No Purchase Necessary. 18+

Void where prohibited by law.

See Terms of Service/Terms of Conditions/Terms of Use.

No Purchase Necessary. 18+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.

Chanced.com

280 Coins

Mega Boost: Up to 280 Free Sweep Coins + 2.8M Gold Coins on First Purchase

No Purchase Necessary. 18+

Void where prohibited by law.

See Terms of Service/Terms of Conditions/Terms of Use.\"

No Purchase Necessary. 18+ Void where prohibited by law. See Terms of Service/Terms of Conditions/Terms of Use.