Detroit Lions vs Washington Commanders Prediction, Odds and Picks for Sunday, 11/09/25

The Detroit Lions suddenly find themselves in a jam-packed race in the NFC North as they prepare to visit the Washington Commanders in Week 10 of the NFL season on Sunday afternoon. Detroit has dropped 2 of its last 3 contests — and following last week’s setback against Minnesota, all 4 teams in the division are separated by just a single game. It goes without saying that the Lions (5-3) will be playing with extreme urgency this weekend. That is part of the reason why my Lions vs Commanders pick is on the visitors to win and cover. It’s not like head coach Dan Campbell’s squad is in crisis mode. Its result against the Vikings in Week 9 is the only loss that can even come close to being considered a “bad” one; Detroit’s other 2 are at Green Bay and at Kansas City.

A date with Washington — even on the road — should be just what the doctor ordered for Detroit. Quarterback Jayden Daniels infamously suffered a dislocated elbow while trailing 38-7 with fewer than 8 minutes remaining in last week’s blowout loss to Seattle. Daniels is obviously out, meaning Marcus Mariota will be back under center for the Commanders. Mariota has plenty of experience and has already started 3 games this year, but he is not anything more than a game manager at this point in his career. When the Commanders are so inferior to the Lions at most positions, you would think the QB would have to do something special to make up for those deficiencies. Mariota, though, is not that guy. If anything, it’s the Lions who have a significant quarterback advantage with Jared Goff. Give me Detroit to win big.

Detroit Lions vs Washington Commanders prediction: Lions -8.5 (-105) available at time of publishing. Playable at that number.

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