Green Bay Packers vs Detroit Lions Predictions, Odds & Expert Picks for Thanksgiving NFL Week 13 2025 for Today, 11/27/25

Thanksgiving Day features a trio of excellent NFL games, and one of the most consequential matchups of the weekend comes in the NFC North, where the Detroit Lions are set to host the Green Bay Packers in a rematch of a Week 1 contest in which Green Bay dominated the proceedings. Both of these teams have been up-and-down all season long, with the Lions struggling to generate consistent success against strong defenses without the services of Ben Johnson as offensive coordinator, while the Packers are also searching for more consistency on a week-to-week basis on offense. Even in last week’s convincing win over Minnesota, Jordan Love and company were still held to less than 300 total yards of offense and largely benefitted from being plus-three in turnovers. However, what Green Bay does have is a very strong defense, which has the ability to generate pressure on Jared Goff and force the veteran quarterback into mistakes, much like we saw in the Week 1 meeting between these teams. As long as the Packers can somewhat limit the effectiveness of Jahmyr Gibbs on the ground, they should do a solid job of getting this Detroit offense off the field.

As for the hosts, the Lions have typically been an excellent team at home in the Dam Campbell era, but it has been tough sledding for Detroit in its recent home games. In fact, the Lions have been struggling against inferior competition, with Detroit losing outright as a significant favorite to the Vikings and needing overtime to get past the lowly Giants last week. This is not the same offense that we are used to seeing out of the Lions, and Johnson’s absence has clearly been felt in the first season with a new play-caller at the controls. On the other side of the ball, Detroit’s defense has allowed a combined 54 points in its last 2 home games against the likes of J.J. McCarthy and Jameis Winston. That doesn’t bode well for the Lions in this NFC North showdown.

Packers vs Lions prediction: Packers ML (+125) available at time of publishing. Playable to +115.

Now you can bet any of our Packers vs Lions predictions at FanDuel Sportsbook, which has a great new-customer offer to take advantage of. If you sign up for FanDuel right now, you earn a welcome bonus worth up to $300 if your first $5 bet wins! 🔗 to join FanDuel right now and learn more.

As of publication, Brock Wright is questionable heading into Thanksgiving Thursday’s matchup against the Packers. He sustained a neck injury in the 2nd quarter of last week’s win over the Giants but finished the game, playing 60 snaps against New York on Sunday. He didn’t participate in the Lions’ walkthrough on Tuesday, so his status is very much in question. Nonetheless, without Sam LaPorta for the rest of the season, Wright gets plugged into a loaded offense that scored 4 touchdowns in an overtime win last week.

The Packers do not call a whole lot of designed runs for their quarterback, but Love will probably be under duress a fair amount on Thursday – forcing him to improvise. It would be no surprise if he is forced to tuck it and run more than a few times in this matchup against Aidan Hutchinson and a Detroit defense that ranks eighth in the NFL with 32 sacks (Hutchinson has 8.5). The Lions have faced the second-most QB rushing attempts in the entire league (63), which have turned into 212 yards. Love has recorded double-digit rushing yards in 7 of the last 10 outings. Against Detroit he produced a 23-yard performance last season and a 39-yard effort during the 2023 campaign.