Houston Texans

Houston Texans vs Tennessee Titans Prediction, Odds and Picks for Today, 11/16/25

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Texans
4-5
Texans
Today
Titans
1-8
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Tennessee Titans
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Texans vs Titans Pickswise Expert Predictions

Point Spread Pick
HOU Texans Win -6.0(-105)

An AFC South battle here as the Tennessee Titans host the Houston Texans. The Titans fired Brian Callahan a few weeks ago to try to give the team a spark, but so far that hasn’t materialized. They’ve lost each of their 3 games since switching to interim coach Mike McCoy, by an ugly combined score of 96-47. The defense has been consistently terrible, while Cam Ward continues to play alarmingly poorly for a number one overall pick, no matter how bad his circumstances are.

On the flip side, the Texans started slow but are coming on strong, even managing to win a shootout with Jacksonville last week despite CJ Stroud being out with a concussion. Stroud is going to miss this one too, but there’s no need to overreact like oddsmakers have. Davis Mills is a competent NFL quarterback, and he showed that while throwing for 292 yards and two touchdowns last week in the comeback win against the Jags.

Houston has gone 4-2 in their last 6, with the only two losses in that span coming in one possession games to very good Seahawks and Broncos teams. 3 of their 4 wins in that span have come by 11+, and all of them have been by at least a touchdown, so they’ve been playing some genuinely good ball lately. The same can’t be said for Ward, who is completing less than 60 percent of his passes, averaging just 6.0 yards per attempt, with more interceptions than touchdowns. In addition to that he’s also taking a truly ridiculous amount of sacks, absorbing 38 across 9 games.

Texans -6 at publishing.

Game Totals Pick
Under 37.0(-110)

This game has the potential to be played at a snail’s pace. We’ve got a backup quarterback on one side, and arguably the league’s least productive quarterback on the other side. Davis Mills is making just his second start of the season, and while he’s competent enough, he’s also never going to light it up. Especially not on the road against a division opponent. Houston knows they’re the favorite in the game and that they can win this one with their defense by waiting for Cam Ward to make mistakes, so I expect them to be running the ball a ton here which will keep the clock churning.

Speaking of Ward, he’s having a disastrous rookie year no matter how you try to spin it. He’s taking over 4 sacks per game, with more picks than touchdowns, with truly anemic completion percentage and Y/A stats. Last week against the Chargers he completed 12 passes, and still some in the media will try to convince you he’s showing promise. To be fair to him he’s working with pretty much zero weapons, another point in favor of the under here. Both these teams are very familiar with each other and need this one like blood, so I think we’re going to see an ugly physical affair here.

Under 37 at publishing.

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Andrew Ortenberg

I'm an NFL handicapper here at Pickswise who was raised in a household full of sports fanatics. Since I unfortunately never had LeBron James' jumping ability I wasn't able to make it to the NBA, and chose writing about sports as the next best thing. An avid sports bettor myself, I'm excited to get to write about the industry as it gets set to take off across the country. Buckle up. For Andrew Ortenberg media enquiries, please email contact@pickswise.com.
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