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Indianapolis Colts vs San Francisco 49ers predictions for Sunday, 10/24/21

Updated: 5:00 AM ET Oct 25, 2021

Levi's StadiumNBC

2-4

Colts

8:20 PM ETSun Oct 24

2-3

49ers

Andrew Ortenberg

Updated: 5:00 AM ET October 25, 2021

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I'm an NFL handicapper here at Pickswise who was raised in a household full of sports fanatics. Since I unfortunately never had LeBron James' jumping ability I wasn't able to make it to the NBA, and chose writing about sports as the next best thing. An avid sports bettor myself, I'm excited to get to write about the industry as it gets set to take off across the country. Buckle up. For Andrew Ortenberg media enquiries, please email contact@pickswise.com.

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Indianapolis Colts vs San Francisco 49ers predictions for Sunday, 10/24/21

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