Los Angeles Rams vs Baltimore Ravens Prediction, Odds and Picks for Today, 10/12/25

It looks like the Baltimore Ravens will once again be without Lamar Jackson as they look to stop their slide and stem the bleeding against the Los Angeles Rams. For several reasons, I don’t expect that to happen. Cooper Rush looked woefully in over his head last week as Baltimore got pummeled by a mediocre Houston team, and it’s quite clear that Jackson was the glue that was holding together a ship that was leaking heavily. The defense is just as big of a problem as the offense, most recently getting torched by a Texans team that had been struggling to move the ball previously.

Jackson is far from the only significant injury the Ravens are dealing with, either, as Chidobe Awuzie and Roquan Smith — 2 key pieces of the defense — have both been ruled out for this one. Zay Flowers is questionable. Rush is coming off a 3-interception disaster, and I haven’t even gotten to how good the Rams have been playing recently. Los Angeles is 3-2, but it is inches away from being 5-0. The Rams’ only 2 losses have come to the Eagles on a blocked kick return touchdown on the final play of the game and to the 49ers in overtime by a field goal.

Matthew Stafford is once again playing at an elite level, most recently throwing for 389 yards and 3 touchdowns. The week before that he threw for 375. In other words, the old guy’s still got it. The last time Los Angeles was a big favorite, it went out and took care of business by beating the Titans by 14 on the road. I expect the Rams to take care of business once again.

Los Angeles Rams vs Baltimore Ravens prediction: Los Angeles -7 (-110) available at time of publishing. Playable at that number.

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I don’t feel great taking the over in a game involving Cooper Rush, but that’s what I have to do. The Rams look like they’re going to be playing in a lot of shootouts this year, as Matthew Stafford looks as good as he ever as while their defense has been somewhat of a sieve. Last week they let Mac Jones score 26 on them, and they also let the sputtering Eagles’ offense have their best game of the season against them.

Rush isn’t as bad as he played last week, and he had a 12-to-5 TD-to-INT ratio during his action with the Cowboys last year. I think he’ll do just enough to help send this one over, since I expect the Rams to be scoring mostly at will. Baltimore’s defense has been a huge disappointment, and Roquan Smith and Chidobe Awuzie have both been ruled out for this one. Incredibly, the Ravens have given up at least 37 points in 4 of their 5 games. That’s hard to do, and the only team they have held to fewer than 37 this season is the Browns.

Los Angeles Rams vs  Baltimore Ravens prediction: Over 44.5 (-110) available at time of publishing. Playable at that number.

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