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Los Angeles Rams

Los Angeles Rams vs Carolina Panthers Predictions, Odds & Expert Picks for NFL Week 13 2025 for Today, 11/30/25

Bank of America StadiumFOX
Rams
Rams
Today
Panthers
Panthers
WWWWW
Last 5
LWLWL
9-2Record6-6
8-3-0ATS Record7-5-0
4-7O/U Record6-6
Carolina Panthers

Rams vs Panthers Best Bets

Point Spread PickBest Bet
CAR Panthers +10.5(-110)

The Los Angeles Rams (9-2) remain on fire after blowing out Tampa Bay last Sunday 34-7 as 7.5-point favorites to grab their 6th consecutive victory. The Rams own the best record in the NFC heading into Week 13, while scoring at least 34 points in 4 of the past 5 games. L.A. looks to avoid a letdown with a trip out east against the Carolina Panthers (6-6), who return home following a 20-9 loss at San Francisco.

The Panthers haven’t lost consecutive games since the first 2 weeks of the season. Carolina is 4-0 straight-up and against the spread off a defeat since losing at Arizona in Week 2. Among those victories, the Panthers shocked the Packers as 13.5-point underdogs in Week 9, and home underdog upsets of Atlanta in Week 3 and Dallas in Week 6. Carolina seeks consistency from QB Bryce Young, who has been held to less than 200 passing yards in 8 of the last 9 games. Also, the Panthers have not suffered back-to-back ATS defeats this season, as Carolina has done a nice job of being competitive off a loss.

Rams QB Matthew Stafford is the MVP front-runner, throwing for 2,830 yards, 30 touchdowns, and only 2 interceptions. Stafford has posted multi-touchdown passing efforts in 9 of 11 games, while the Rams have not lost away from SoFi Stadium since the Week 3 meltdown at Philadelphia. The Rams begin a stretch of 4 of the next 5 games on the road, while not leaving the state of California since October 19 when they faced the Jaguars in London. The Panthers have shown a nice knack of rebounding this season, and this can be a down spot for the Rams off a huge Sunday night blowout of the Buccaneers.

Rams vs Panthers best bet: Carolina Panthers +10.5 (-110) available at time of publishing. Playable to 10.

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Kevin Rogers

Rams vs Panthers Pickswise Expert Predictions

Game Totals Pick
Over 44.5(-110)

The Rams have allowed the fewest points in the league at 179, while going 4-1-1 to the under in the last 6 games. Los Angeles limited Tampa Bay to 7 points, one week after the Bucs scored 32 points at Buffalo. The Rams head east to face the Panthers, who were held to single-digits for the 3rd time in 5 games after scoring just 1 touchdown in a 20-9 loss to the 49ers.

The Panthers are averaging 31.2 points per game in the 4 games off a loss, while the lowest output came in a 16-13 win at Green Bay in Week 9. Carolina’s offense has scored a total of 16 points in the past 2 home losses to New Orleans and Buffalo, but QB Bryce Young missed the 40-9 blowout to the Bills with an injury. The Panthers are on a 3-1 under run the past 4 games, while allowing 20 points or less 3 times in this stretch.

Now it’s a different animal facing the Rams, who are averaging 30.6 points per game in 5 contests away from SoFi Stadium. The defense has yielded 10 or less points in 4 of the past 6 games, so we’ll see if that continues against a Carolina offense that has struggled at home. However, the bounce-back trend for the Panthers off a loss is hard to ignore. The total sits at 45, as the Rams are 3-2 to the over on the road, while Carolina is 3-1 to the over in its last 4 home contests. The points can be scored here with the Rams’ offense on fire, but the Panthers can possibly break through as well and we can see a high-scoring contest in Charlotte.

Rams vs Panthers prediction: Over 44.5 (-110) available at time of publishing. Playable to 45.5.

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Kevin Rogers
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Kevin Rogers

Kevin covers the NFL for Pickswise from sunny south Florida. He has been handicapping the NFL professionally since 2007, as well the NBA, MLB, NHL, college football, and college basketball. He looks forward to a profitable season at Pickswise.
@RogersPicks
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Money Line

The Rams have won 3 straight road games.

Point Spread

The Rams are 9-1 against the spread in their last 10 road games.

Game Totals

The Over is 12-8 in the Rams' last 10 games on the road and the Panthers' last 10 at home combined.

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