Los Angeles Rams vs Seattle Seahawks Prediction, Odds and Picks for Tomorrow, 12/18/25

Evidently both the Rams and Seahawks were mentally distracted in Week 15 since neither outfit put out their best performance, but one certainly played better than the other. The Rams started slow against the Lions, tied at halftime 17-17. Then they took off, scoring 17 unanswered points in the third quarter while cruising in the fourth. Even in a high-stakes, emotional battle, Matthew Stafford and his colleagues had no problem moving the ball against a fiery, motivated Lions’ roster. Los Angeles accrued 514 total yards and 30 first downs. They also scored a touchdown on four of six red-zone possessions. It was ultimately another sterling performance by a group that’s as intimidating as any in the NFL. An asterisk from the Week 15 victory was the unfortunate loss of Devante Adams, who incurred a hamstring injury. He’s unlikely to play Thursday, which is a big loss, especially near the endzone (Adams has a league-high 14 receiving touchdowns this season).

The Seahawks were clearly looking ahead to this heavyweight matchup in Week 15. Sam Darnold and the offense generally underwhelmed, producing just 18 points, 314 total yards, and 15 first downs. The Colts’ defense came to play, as did the Seahawks, who allowed just 3.7 yards per play and 215 total yards to the Phillip Rivers’ led visitors. The Seahawks defense has an edge in Week 16, since they outrank the Rams in both EPA per pass (5th) and EPA per rush (1st). 

Los Angeles and Seattle will enter Week 16’s showdown with 11 wins each, competing not only for the NFC West crown but potentially for the #1 seed in the conference. In that sense, this is akin to a playoff matchup, with much riding on the result. Normally we side with the more experienced leadership in those instances, which means typically we’d pick Super Bowl winning coach Sean McVay and Matthew Stafford. But these circumstances are a bit different.

In a “prove-it” game, Darnold and the offense collapsed in Week 11. Although they gained plenty (414 yards), Darnold threw four interceptions, stonewalling several trips in the red-zone (they were just 1-4). But statistically the Seahawks outmatched the Rams in nearly every category except turnovers, including a 26-12 lead in first downs and better efficiency on third downs, too (7-16 compared to LAR’s 2-11). Los Angeles also went scoreless in the third and fourth quarters, held in check by a stingy Seahawks’ defense. Back in Seattle and with vengeance adding extra motivation, we must side with the home team.

Los Angeles Rams vs Seattle Seahawks prediction: Seahawks ML (-108) available at time of publishing. Playable at that price.

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