New Orleans Saints vs Chicago Bears Prediction, Odds and Picks for Today, 10/19/25

Two quarterbacks from the 2024 NFL Draft class will face off here as Spencer Rattler and the New Orleans Saints get ready to take on Caleb Williams and the Chicago Bears. Chicago is coming off their best win of the season after beating Washington on Monday Night Football, and I think now is the time to sell high. Sure the Bears are on a three-game win streak, but that’s highly misleading.

To start this win streak off they beat a mediocre Cowboys team that just lost to the Panthers, and the next two wins were by just a single point each against the Raiders and Commanders. Right before that, they got demolished while giving up 51 points to the Lions, so let’s not get carried away with Bears excitement. They trailed most of the game against a really bad Raiders team, and I don’t see any reason for them to be such a large favorite here against the Saints who aren’t completely helpless. New Orleans just played a pretty tight game against the Patriots where Rattler averaged 8.7 yards per attempt with no turnovers against a good New England D, and the week before that they beat a suddenly resurgent Giants team by double digits.

Rattler has quietly been having a pretty solid season, and most importantly has been taking care of the ball, with only 1 interception through 6 games. The Saints are better than their record indicates, and they had a really difficult schedule to open the season. Alvin Kamara just got in a full practice on Friday for the first time in two weeks, so it seems like he is thankfully pretty much back to full health which will be a big boost to the offense.

New Orleans Saints vs Chicago Bears prediction: Saints +4.5 (-110) available at time of publishing. Playable at that number.

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I’m also playing the over here since I have zero confidence in either defense. Chicago’s defense has been a sieve this year, and in 4 of their 5 games this year there have been at least 49 points scored. And in the other there were still 45. Last week they gave up 24 to Washington despite the game being played in rainy conditions and with Jayden Daniels not doing much, and the week before they gave up 24 as well to the struggling Raiders.

There’s only been one game this season where Chicago didn’t give up at least 24, and they have the 51-point outburst surrendered to Detroit on their resume. New Orleans also doesn’t inspire much confidence on defense, and they just got picked apart by Drake Maye last week to the tune of 10 yards per attempt. And that was with a couple big Maye completions getting called back on questionable penalties.

Their D fared fairly well against Jaxson Dart in his first career road start two weeks ago, but right before that they gave up 31 and 44 to the Bills and Seahawks respectively. Alvin Kamara being back at full strength will be a big boost to the Saints’ offense, and this one has sneaky shootout potential.

New Orleans Saints vs Chicago Bears prediction: Over 46.5 (-110) available at time of publishing. Playable at that number.

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