New Orleans Saints

New Orleans Saints vs Los Angeles Rams Prediction, Odds and Picks for Today, 11/02/25

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Saints
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Rams
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1-7Record5-2
2-6-0ATS Record5-2-0
3-5O/U Record3-4
Los Angeles Rams

Saints vs Rams Pickswise Expert Predictions

Point Spread Pick
LA Rams -14.0(-110)

The Tyler Shough era is officially upon us in New Orleans, as the Saints will give the rookie quarterback the reins for the first time against the Los Angeles Rams. Spencer Rattler is hitting the bench, and while Rattler wasn’t exactly putting up All-Pro numbers, I’m skeptical this will help New Orleans’ offense in the short term. This is clearly a long term play to see what the second-round pick has, and to see whether the Saints need to draft another quarterback next April.

There’s no reason to believe that Shough is ready to come in and look like an NFL starter from Game 1 based on what we saw in the preseason and training camp, when he was very much up and down. Say what you want about Rattler, but he has actually been competent and has protected the ball well this year, and I think this is a big downgrade at least for the time being. Shough is being thrown out on the road against a tough Rams team that just had a bye week to heal up and prepare for this one. Los Angeles won back-to-back games entering the bye by a combined score of 52-10.

The Saints, on the other hand, are 1-7 — most recently getting drubbed 23-3 at home to a beat-up Bucs team. Their only win of the season has come at home against the lowly Giants right at the beginning of Jaxson Dart’s time as the starter. Four of their last 5 defeats have been by at least 12 points, so I don’t worry too much here about laying the large spread with the Rams — who have certainly shown their capable of running up the score. In their most recent game against the Jags in London, they won by 28 as Matthew Stafford threw for 5 touchdowns.

New Orleans Saints vs Los Angeles Rams prediction: Rams -14 (-110) available at time of publishing. Playable at that number.

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Andrew Ortenberg
Game Totals Pick
Under 44.0(-110)
Even though I’m laying the large spread, I also like the under in this spot because I don’t see the Saints scoring much at all. Tyler Shough is being thrown to the wolves in his first career start, having to go on the road against a defense that has given up 10 total points over its last 2 games. New Orleans scored 3 points last week, and the crazy thing is that Spencer Rattler hasn’t even played that bad this year — the rest of the offense is just atrocious. Alvin Kamara is averaging just 3.6 yards per carry and Chris Olave has been a big disappointment with little behind him.

The Rams just completely stymied Trevor Lawrence and the Jaguars their last time out, holding the Jags to just 7 points while sacking Lawrence 7 times. Los Angeles’ pass rush looks as good as it ever did with Aaron Donald; it is second in the league in sacks. Best of all, it’s not just one guy — the Rams have a bunch of different guys who can beat you, and 6 different players had sacks of Lawrence most recently. Look for a low-scoring affair in this one.

Saints vs Rams prediction: Under 44 (-110) available at time of publishing. Playable at that number.

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Andrew Ortenberg
I'm an NFL handicapper here at Pickswise who was raised in a household full of sports fanatics. Since I unfortunately never had LeBron James' jumping ability I wasn't able to make it to the NBA, and chose writing about sports as the next best thing. An avid sports bettor myself, I'm excited to get to write about the industry as it gets set to take off across the country. Buckle up. For Andrew Ortenberg media enquiries, please email contact@pickswise.com.
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Top Trends
Point Spread

The Rams are 4-1 against the handicap in their last five games at home

Game Totals

The under has cashed in the Saints' last four games

Money Line

The Rams are on a four-game winning streak at home against the Saints

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