NFL Parlays

NFL parlay picks today. Our expert NFL parlays have made +19 units profit so far this season. Get the best odds for NFL parlays and same game parlays you can trust, every week of the 2025-26 NFL season.

Saturday's NFL Week 18 parlay

4:30 PM ETSat Jan 3

4:30 PM ET

CAR Panthers @ TB Buccaneers · Point Spread

CAR Panthers +3.0

Reasoning

Our Analysis

Since the Falcons shocked bettors and beat the Rams on Monday Night Football, the race for the NFC South crown just got more complicated. In simpler terms, Tampa’s chances of making the playoffs just decreased significantly. Even if they win this game on Saturday, they need the Saints to knock off the Falcons (at Atlanta) on Sunday to win the division.

Regardless, motivation will be at its peak on Saturday afternoon as these 2 NFC South rivals clash in the final week of the 2025 NFL season. The Bucs’ demise has been startling. Halfway through the season, they looked like one of the league’s most dangerous outfits (they were 6-2 entering Week 10). They have only 1 victory since, and December has churned out one perplexing loss after another (at home fails against New Orleans and Atlanta and last week falling to the Fins in Miami). They also dropped their first clash against the Panthers just 2 weeks ago, thanks to a Baker Mayfield interception on what could have been the game-winning drive. Since Week 10, they’ve been the favorite in 6 out of 8 contests, a designation they’ll receive once again at home in this crucial battle. Not once have they covered the spread since Week 10, either.

Injuries to key players on both sides of the ball have been their biggest challenge, but we also can’t ignore the absence of Liam Coen, the distinguished offensive coordinator who left to coach the Jaguars this season. Jacksonville now sits 12-4 and is one of the top seeds in the AFC.

The Panthers have rarely played consistently well this season, either, but their journey to the top of the NFC South has been far more impressive than their rival. Halfway through the season, they were 4-4, a nice surprise considering their downtrodden years prior. Key wins at Lambeau Field, at Atlanta, at home against the Rams and most recently against the Bucs have carved a path for Dave Canales and his roster. Much to the chagrin of Tampa and their other rivals, the Panthers simply won’t go away. Anchored by a defense that plays its best in the clutch (they’re 13th in opponent red-zone success) and a formidable rushing attack (11th in rush yards per game), they’ve only lost consecutive games once this season, in Weeks 1 and 2. In his 3rd year, Bryce Young has also emerged as a more dependable thrower, although his numbers are never eye-popping (21st in yards, 24th in turnovers, 23rd in total QBR).

It’s really hard to support Tampa right now, especially as the chalk. They’re just 2-7 against the spread as the favorite this season, while Carolina revels in the underdog role (8-5 ATS). All things considered, the Panthers feel like the right side to be on.

Panthers vs Buccaneers prediction: Panthers +3 (-110) available at time of publishing. Playable to 2.

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8:00 PM ET

SEA Seahawks @ SF 49ers · Point Spread

SEA Seahawks -1.5

Reasoning

Our Analysis

NFL schedule makers have done it again, as 2 NFC titans will clash for not only the claim of NFC West champions but the #1 seed in the conference. Both rosters are rounding into their best form to end the season. As if this game wasn’t hard enough to predict, the home team has been great in front of their fans, 5-2 straight up, while the Seahawks have been road warriors all season (7-1). In a span of 2 days, Seattle has moved from a slight underdog to a slight favorite. We wouldn’t be surprised at all if that switched again before kickoff.

Look at either program, and you will see nothing but wins throughout December and beyond. After a 2-point loss to the Rams in Week 11, Seattle has won 6 straight games. They had a memorable comeback win against the Rams in the rematch and proceeded to display impressive margin victories over the Vikings, Falcons and Panthers in recent weeks. Just 2 years in, coach Mike Macdonald has taken full advantage of his defensive talent, the side of the ball where he has the most expertise, and newcomer Sam Darnold proved his worth immediately. He’s looking to achieve his 2nd straight 14-3 season with 2 different teams. Even better, the Seahawks are one of the healthiest teams in the NFL, sprinting full speed towards the postseason with very few holes on their roster. Their offense has sputtered here and there down the stretch (now 16th in total offensive EPA), but they have more than enough firepower to get the job done when they need to.

Like the Seahawks, the 49ers’ last loss was against the Rams in Week 10, but since then, they’ve been relatively flawless. An easier schedule has certainly helped, but with Brock Purdy back in the fold, San Francisco has gone 6-0, winning by an average margin of +14.3 points per game. That doesn’t happen by accident. Even with virtually no defense last Sunday, the 49ers scored at will on the Bears at home, putting up 42 points and going 5-5 in the red zone. Their Achilles heel will continue to be their defense, which was heavily injured midway through the season, but their offense is firing on all cylinders (now 6th in total EPA).

This is a very tough pick and would probably work better as a teaser (San Francisco from +1.5 to +7.5 feels ideal), but since we must pick a side, we’ll go with the visitors, who are a more complete operation right now.

Seahawks vs 49ers prediction: Seahawks -1.5 (-110) available at time of publishing. Playable at that number.

BET +227 NOW WITH

Andrew Wilsher

What Is An NFL Parlay?

An NFL parlay is a type of bet where you combine multiple selections into a single wager. For an NFL parlay to win, all of the selections or bets need to win. While the difficulty of winning an NFL parlay increases with each selection you add, the odds can also greatly increase. To calculate the odds of a parlay you multiply the odds of the individual selections so the more selections, the bigger the parlay odds. You can also make use of our Parlay Calculator to take care of all of the math for you. For more on Parlays be sure to check out our Parlay betting guide.

Our experts will highlight the best NFL Predictions to combine into an NFL Parlay, offering you even more variation into how you want to wager on this week’s NFL action.

NFL Parlay Picks

Here at Pickswise, we have free NFL parlay picks every week of the NFL season. Our free NFL parlays include both traditional multi-game parlays which include our best parlay picks from the most popular markets including money line, spreads, and totals, as well as our NFL Same Game parlays. Each of our free NFL parlays will come with a full analysis for each leg, as well as the best odds available from all of the top online sportsbooks. Check back every week including for those primetime parlay picks on Mondays, Thursdays, and Sunday Night Football.

NFL Parlay Strategies & Tips

Parlay Bets despite their popularity can be one of the most difficult, but potentially most lucrative bets, with increased difficulty with each selection you add. It’s important to remember that over the course of the NFL season even experts will very likely lose more parlays than they win. However, the nature of parlay betting means the wins you do get turns more profit.

Here are some quick tips to better your chances of winning long-term with your NFL Parlays

Stick to 2, 3, or 4 team parlays – Any more than this will often not be profitable long term despite the increased parlay odds. Multiple sportsbooks and NFL betting experts report the win rate of 2-leg NFL parlays to be 49-52%, while 3-legs hit at about 27-30%, 4-legs at 15% and 5+ legs are successful less than 10% of the time.
Shop around for odds – Not all online sportsbooks offer the same odds, and while there is often only a marginal difference if you can wager three picks at -105 each instead of -120, your payout would be $744.21 instead of $616.20 to a $100 stake.
Avoid same-side NFL Parlays – Although popular amongst NFL bettors, parlaying heavy favorites or multiple overs bets for example, are loved by sportsbooks as they generally offer very poor value to the bettor.
Manage your bankroll – Being disciplined with your bankroll is key long term as not all parlays will win, particularly in the NFL, but if you keep your stake consistent, at odds of around 6/1, you only need to win 1 in 7 parlays to break even, any better than that is profit.

NFL Picks and Parlays

At Pickswise our experts do hours of research and statistical analysis ahead of every NFL game week, providing professional insight into the array of NFL betting markets available and where you can find the value. Our NFL parlays come with a full reasoning for each leg so you can feel confident using our ready-made parlays yourself.

If you prefer to put your own parlays together but want some inspiration or expert opinion on the selections to make, our range of NFL Picks and NFL Prop Bets are the perfect companions to our NFL parlay picks and exactly what you’re looking for. Not only that, our NFL Best Bets are an excellent starting point for your parlays, or the perfect way to round out that NFL Parlay needing one more selection.

How to bet on NFL Parlays

Betting on NFL picks and parlays is a quick and simple process with any online sportsbook. To create a parlay, you simply have to add multiple selections to your bet slip and click the parlay option before placing your wager.

Due to the popularity of NFL betting and also NFL parlays, sportsbooks pay a considerable amount of attention to these markets, and in shopping around you can find great variations in odds, spread lines, and often price boosts or bonuses such as Parlay insurance whereby you get your stake as a bonus bet if only one leg lets you down. Shopping around for these advantages is key to having long-term success with NFL parlays.

Unsure where is best to place your NFL parlay bets? Head over to our online sportsbook promotions page where we break down all the information and latest promo codes you’ll need to know to unlock bonuses and make your NFL betting easier.

What is an NFL Teaser Bet?

One of the ways to avoid the frustration of losing an against-the-spread bet by a point or two is with NFL teaser picks. For example, in a 2-team teaser, you get 6 points placed in your direction (-7 spread becomes -1) for both games. The caveat is that both teams must cover for your ticket to be graded a winner and the odds are similar to a single-game bet. Conversely in a parlay, you still wager on two teams but with the original spread and with better payout odds (usually 3:1). Teasers can be parlayed with 2,3,4,5 teams or more. NFL Teasers are a significant way to boost your parlays win probability as around 25% of NFL games end with a margin of exactly 3 or 7 points, so crossing those margins offers great value.

What Is A Same Game Parlay

A Same Game Parlay is just like a regular parlay wager, except all selections come from prop bets within one specific game. The obvious positive of a Same Game Parlay is that by combining multiple selections you can go for an even bigger win with the odds increasing with each selection.

Bettors will often use Same Game Parlays to wager on correlated props, and if you get it right the payouts can be huge. Take, for example, a team facing a poor pass defense with an elite QB, in that spot, you might take the QB to hit over their passing yards total and you can also parlay that with their favorite wide receiver to score anytime and the team to win.

There are some restrictions or odds adjustments on correlated bets within a same-game parlay but it’s still a great way to improve the probability of your NFL parlays being successful in the long-term.

How To Bet On A Same Game Parlay

With the Same Game Parlay’s increasing popularity, the majority of leading online sportsbooks now offer them across a number of sports, including the NFL. Some refer to them as One Game Parlays and Single Game Parlays, which are different in name, but the same in concept.

To bet on a same game parlay simply head to your preferred online Sportsbook, or where you can get the best odds for your picks. Unsure of the best online sportsbook for the NFL? Check out our guide to the best NFL betting sites today.

To bet a Same Game Parlay you must first click on the game you want to place a bet on, and then add each selection to your betslip. The Same Game Parlay odds update with each pick. Once you have added all of your selections, enter the amount you wish to wager and hit ‘place bet’. And that’s it, you’re on!

New to betting? or not yet registered with one of the sportsbooks currently offering Same Game Parlays? Get the latest promo codes for FanDuel, BetMGM, DraftKings, Caesars, bet365 and Fanatics to unlock welcome bonuses for the 2025 NFL season.

NFL Parlays: Betting small to try to win big

Bet small, win big. That’s the aim of every NFL parlay and our team of experts spend hours each week crafting what they believe to be the perfect parlay to deliver a nice payout. Our handicappers are among the best in the business at doing just that, with each leg the product of intensive analysis from numerous members of the Pickswise capping team. Our record speaks for itself when it comes to NFL parlay expertise, throughout the 2023 season our NFL parlays had scored 38.5 units in profit.

Andrew Wilsher, Pickswise Managing Editor

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NFL Parlays FAQs

Can You Parlay NFL Win Totals?

You cannot parlay NFL Win Totals bets as the outcomes of the events are closely correlated. If you were to bet the Overs on the Saints, but the Unders on the Buccaneers for example, and the Saints beat the Bucs twice in a season, both outcomes are likely to increase their chances of winning.

What Is A Parlay Bet In NFL?

A parlay bet in the NFL is when you combine multiple straight bets into one single bet. Every pick within the parlay must win for the ticket to cash, but the odds also increase in line with the risk of adding more picks, making them fruitful if they hit.

Can You Parlay NFL Futures?

You can parlay certain NFL futures before and during the season, but it will vary from sportsbook to sportsbook. One example would be division winners, you can try to hit a big parlay and predict all 8 division winners in a season. Some sportsbooks will also allow you to parlay Player Awards such as Offensive and Defensive Rookie of The Year.

Are NFL Parlays Worth It?

Parlays can be worth it, but it’s also worth keeping in mind that the more picks you have in a parlay the harder it will be to win. However, with the odds of each individual pick multiplying to give you the parlay odds, it allows you to bet smaller units to try and win bigger returns than a straight wager.

What Are The Disadvantages Of A Parlay?

The disadvantage of a parlay is its difficulty to win. While the odds are often great, adding each pick will also increase the risk of the bet winning as every selection has to win for the ticket to cash, a single losing leg with 5 winning ones still returns $0.

Why Are Parlays So Popular?

Parlays are popular because they offer the opportunity of betting small and win big. For example, if you were to parlay 6 teams against the spread, you should expect odds of around +4500 meaning a $50 bet would return $2,300.