NFL Picks

NFL picks for every game of the 2025-26 season. Our NFL expert picks are informed by key betting trends, statistical analysis and years of NFL betting experience. +56.7 units of profit, from 137 winning picks so far this season is the proof.

Our NFL picks this week include against the spread picks for every game in week 9, highlighted by Ravens vs Dolphins on Thursday night football, Seahawks vs Commanders on SNF and Monday Night football, featuring Cardinals vs Cowboys. Also in Week 9, the latest contest between the Buffalo Bills and the Kansas City Chiefs, a match-up that has proved unmissable in recent years. Featuring two of the NFL’s elite Quarterbacks and a re-match of last season’s AFC Championship game.

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Point Spread Pick

DAL Cowboys -2.5(-115)

Reasoning

Week 8 was another routine, poor performance from the Cowboys. Away from AT&T Stadium, Dallas suffered their 4th loss of the season. For their fans, it wasn’t for the meek of heart. In most ways, the Broncos eviscerated the visitors, accruing 44 points and 426 yards on 7.5 yards per play. Through the air, Bo Nix was electric, hitting 8.5 yards per pass and leading Denver to a pristine 4 touchdowns on 5 red-zone attempts. It was yet another indignation of the Cowboys’ defense, a group that was without Trevon Diggs, who’s now on injured reserve, and has been one of the worst units in the NFL all season (31st in opponent yards, points per play, opponent yards and points per game). The good news is that Dallas is a different team at home, especially on offense. In 3 games at “Jerry’s’ world,” the Cowboys have averaged a ridiculous 41 points per game, and they did it against 2 NFC East foes (NYG, WAS) as well as the Packers, who qualify as a top-3 defense according to Pro Football Focus.

The Cardinals rank 24th in the same category, which is our biggest issue with betting on Arizona. Jacoby Brissett looks set to once again be under center, who has played well in 2 starts for Arizona, putting up respectable numbers (599 passing yards, 4 touchdowns, 1 interception) against 2 of the NFL’s best teams (IND, GB). However, no matter what way we look at it, the Cardinals have lost 5 games in a row for a reason. Their offense is often out of sync, and their defense rarely plays up to expectations for a full 4 quarters. Dallas has been a buzzsaw at home, and right now they have the far better quarterback.

Cardinals vs Cowboys best bet: Cowboys -2.5 (-115) available at time of publishing. Playable to 3.

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Game Totals PickBest Bet

Over 53.0(-120)

Reasoning

To allege that the Cardinals might be able to slow down or limit the Cowboys’ offense, we would need substantial evidence to support such a claim. Unfortunately for Arizona fans, that doesn’t exist. While the visiting team has some respectable marks, like their 6th-place ranking in opponent third-down conversion rate (35.29%) and 7th-place ranking in opponent yards per pass (6.5), most data points suggest that they’re average at best. They are 13th in opponent points (22) and 19th in opponent yards per game (335.7), but even that data is somewhat positively skewed since they’ve faced poor offenses like New Orleans, Carolina, Tennessee, and a tremendously-injured 49ers’ roster in Week 3 (and they still lost). Against superior offenses like Seattle, Indianapolis and Green Bay, the Cardinals permitted 27 points per game.

The Cowboys are statistically better than all of those NFL offenses but the Colts, and they’re far better than every program at home. Putting up 41 points per game at AT&T Stadium is one thing, averaging 441 yards at home is another. The addition of George Pickens has meant a significant uptick in production for Dak Prescott and their air-attack, a receiver that started to shine when CeeDee Lamb had to sit out in 4 contests this season. Now Pickens and Lamb are both healthy and apparently thick as thieves, 2 buddies who make it their goal to punish enemy defenses every week. Together they’ve accrued 1,091 yards and 7 touchdowns. On Monday they’ll battle a defense that’s 27th in opponent pass completion percentage (62.05%) and 25th in opponent pass yards per game (234.9). Without any weather interruptions, there is only one way to look.

Cardinals vs Cowboys prediction: Over 53 (-120) available at time of publishing. Playable to 54.5.

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Chris R. Farley

Anytime Touchdown Scorer Pick

T. McBride (ARI) to score a TD(+105)

Reasoning

Nobody has benefited more from Jacoby Brissett filling in for Kyler Murray than Trey McBride. In the 2 games that Brissett has started, McBride has reeled in 18 of 24 targets, 146 yards and 3 touchdowns. As 3-point underdogs on the road to a woeful Cowboys defense, McBride should be a staple in the Cardinals’ offensive gameplan, most importantly in the red zone, where the Cowboys are allowing a touchdown on 69% of red-zone trips, which is in the bottom 5 in the NFL.

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Anytime Touchdown Scorer Pick

M. Wilson (ARI) to score a TD(+250)

Reasoning

Like McBride, Michael Wilson has been a beneficiary of Brissett under center. With Murray at QB, Wilson was averaging fewer than 11 yards per game. Under Brissett, Wilson is up to 42 yards per game and playing over 75% of the snaps. We’re anticipating a negative game script for the Cardinals against a Cowboys offense that can light up the scoreboard — especially with question marks regarding Arizona’s running back room.

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Justin Martin (JutPicks)

Same Game Parlay

Alternate Point Spread

DAL Cowboys -5.5

Anytime Touchdown Scorer

J. Williams (DAL) to score a TD

Player Rushing Yards

B. Knight (ARI) - 50+ rush yds

Reasoning

Dallas Cowboys -5.5 alternate spread over Arizona Cardinals (+122)

This has not been the case in recent years, but the Cowboys are actually better at home than they are on the road this year. Yes, Jerry World has actually been kind to the home team in 2025. Dallas is undefeated (2-0-1) through 3 outings in its own building, while it is 1-4 when it has to travel. Dak Prescott and company are scoring an outrageous 41 points per game at home and should be in line for another huge performance against an Arizona outfit that is ranked #24 defensively overall by PFF.

On the other side of the ball, Jacoby Brissett is starting at quarterback for the Cardinals in place of an injured Kyler Murray. Their passing game was already bad to begin with (third worst in yards per pass attempt), so the visitors could struggle even against a generous Cowboys defense. There really isn’t anything to like about Arizona in this matchup. Give me the ‘Boys to win by a touchdown…and perhaps more.

Javonte Williams to score a touchdown (-160)

The Cardinals have given up almost as many rushing touchdowns (7) as passing (8). In fact, heading into Week 9, they have allowed the 3rd-fewest TDs through the air. As such, it would be no surprise if the Cowboys do their red-zone damage on the ground. That would be nothing new for Williams, who has been a scoring machine. The North Carolina product has already produced 9 touchdowns – 8 rushing, 1 receiving. He found the end zone twice last weekend against Denver, giving him 3 touchdowns in the past 2 contests. Williams has every reason to score at least once against Arizona on Monday Night Football.

Bam Knight to record 50+ rushing yards (-102)

With James Conner and Trey Benson on injured reserve, Knight has only Emari Demercado to compete with in the Cardinals’ backfield. Knight is RB1 on Monday and should be able to capitalize at the expense of a Cowboys defense that is giving up 146.0 rushing yards per game (29th in the NFL) on 4.9 yards per carry. The 3rd-year player out of NC State gained 57 carries on 14 attempts during last week’s loss to the Packers and he has scored a touchdown in 2 of the last 3 games.

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Why Trust our NFL Picks

Through the first eight weeks of the 2025 season our record speaks for itself. Our team of handicappers have racked up 70 winning NFL against the spread and moneyline picks (and 1 push), for +35.4 units of profit. On top of that, our NFL over/under picks have landed on 67 games, for a profit of +21.3 units. When you combine the two, our expert NFL picks have scored +56.7 units of profit so far this season.

Pick	Wins	Losses	Profit (betting units)
Sides (ATS & Moneyline)	70	50	+35.4
Over/Under	67	54	+21.3
Total	137	104	+56.7

We’re coming off a great week, with a profit of +30.2 units in week 8 alone. We had 18 wins from 26 picks. Including 11 winning totals picks.

At Pickswise, every NFL pick is backed by years of betting experience, advanced data analysis, and a proven track record of success. Our team of handicappers studies line movement, injury reports, historical trends, and matchup stats to deliver informed recommendations — not guesses. We publish our results openly, update our predictions as new information emerges, and never hide behind vague analysis. Whether you’re looking for expert spreads, totals, props, or parlays, our mission is simple: give you honest, well-researched picks that stand up over time.

Free NFL Picks Explained

We firmly believe expert NFL picks should be free, so you’ll find our NFL picks today, and every day of the season, right here. We publish our free NFL picks for every game, at least a few days in advance of gameday, so you know who the experts are backing without missing out on the early value in the betting markets.

There’s almost an infinite way to bet on the NFL, from NFL picks against the spread, moneyline, over/under, NFL Parlays, and NFL Prop Bets, there is a bet type for every kind of football fan, so we provide NFL picks for every bet type. Some bettors like to specialize in a single particular type of NFL pick, while others like to have a diverse range and bet on anything they feel is a value pick.

Here at Pickswise, we have something for everyone. Our team of handicappers have a wealth of experience in making NFL picks across all these betting markets, leaving no stone unturned ahead of every game and every pick of the 2025 NFL season. If you’re looking for more information on NFL bet types, You can find our expert breakdown of each below.

NFL Picks Against the Spread

The most popular way to bet on the NFL is against the spread (ATS). With these wagers, you are not picking a simple winner or loser of a game. Instead, ATS betting is placing your money that Team A wins by a certain amount of points or that Team B will keep the game closer than oddsmakers expect, in other words, not lose by that same amount of points.

For Example

Philadelphia Eagles -7 – Philadelphia must win by 8 or more points to cover the spread.
Chicago Bears +7 – Chicago must win, or lose by 6 or fewer points to cover the spread.
Tie Scenario – If the game ended 27-20 to Philadelphia, the spread would be a tie, or a push and stakes would be returned.

NFL spread betting trends 2025

The team that covers the spread wins the game outright around 80% of the time.
Road teams going into games as the favorite have covered the spread at 64% so far this season
Teams coming off a blowout loss (20+ points) tend to rebound against the spread, 57% of the time.

Free NFL Over / Under Picks

Another exciting way to still get in on the NFL action is with totals wagers. In these bets you don’t take a side, but whether the two teams will combine to score over or under the total number of points that the oddsmakers have set. Already since sports betting has been legalized we’ve seen many occasions where a hail mary, missed FG or XP has cost over or unders bettors, so be prepared to be in for the long haul with your totals bets. We preview every game of the NFL season, providing insight into the game as a whole alongside expert NFL picks so you can make informed NFL totals bets.

NFL over / under betting trends

Overall, unders have proven the value pick in recent seasons, as defenses have caught up with scoring trending down since 2021
Unders bets have the edge in divisional games, landing 57% of the time. This trend gets stronger late in the season (week 13 onwards), especially in cold weather conditions.
Unders bets have landed on 58% of primetime games, as public betting tends to have a bias for the overs in these games.

Money Line NFL Picks

Ask any seasoned NFL bettor and they’ll tell you that ATS betting is exciting, but can also be frustrating. It is important to keep in mind that NFL teams only need to win by one, of course, they’d love to win by more, but they’ll change their schemes late on to secure a win, not to ensure they cover the spread. Your research could have given you the right side, but if they win by 6 instead of 7 your -6.5 bet is a loss. Therefore a lot of bettors like to keep it simple and take our expert NFL Money Line picks and bet on the NFL straight up.

NFL Moneyline betting trends

Through the first 4 weeks of the 2025 season 6+ point favourites have been strong straight up, with a 16-2-1 record
Short underdogs (+1 to +3 on the spread) win outright 43% of the time, offering better value on the moneyline than the spread
Underdogs in lower scoring road games (less than 42 total points) win outright 39% of the time, but often at better prices than this record suggests.

2025-26 NFL Schedule

This will be the 106th season in league history and is set to kick off with the NFL Kick-Off game on Thursday, September 4, hosted by the defending Super Bowl Champions Philadelphia Eagles, who take on the Dallas Cowboys. The regular season will come to a conclusion on January 4, 2026 with the NFL Playoffs scheduled to begin the following weekend on the 10th, 11th & 12th of January 2026. Super Bowl LX is scheduled for February 8, 2026, at Levi’s Stadium in San Francisco, California, the home of the 49ers.

NFL Playoff Picks

You can find our NFL picks for the 2026 Playoffs, right here, for free. Wildcard Weekend is scheduled to start January 10, upon the conclusion of week 18 our experts start to make their picks and predictions for the first round of the playoffs and after each round is concluded we prepare for the coming weekend, all the way up to the Super Bowl.

NFL Playoff Picks
NFL Wildcard Weekend Picks
NFL Divisional Round Picks
NFL Conference Championship Picks

NFL Expert Picks

Our NFL Football picks will be for every game throughout the regular season, with primetime games and the top matchups each week getting additional expert coverage which will extend to every playoff game. These NFL Football picks will come alongside analysis and the latest stats and trends to consider when betting. You can also find our NFL Best Bets for the top plays of the week and a confidence rating for our expert handicapper.

Looking for alternative football picks? then head to our College Football Picks page, where you’ll find the same level of expertise from the Pickswise handicapping team for all the headline games in the 2025 NCAA football season.

More Than Just NFL Football Picks

We also specialize in every major North American sport including the MLB, NBA, NHL, College Football, and College Basketball. Check out our site every day for some of the best bets in every major athletic contest and make sure to follow us on social media as well.

Andrew Wilsher, Managing Editor of Pickswise

Statistical Approach to NFL Picks

It’s our goal to provide you with the best NFL picks in the market. Our expert handicappers are all specially selected and assessed prior to joining the team to ensure their analysis. experience and results are among the best in the industry. Each capper will put hours of research into each pick and many have built statistical models to find their moneyline, spread and over/under picks so you don’t have to. Check out all of our cappers’ free NFL picks here every week of the season.

Andrew Wilsher, Pickswise Managing Editor

NFL Picks FAQs

How Do You Pick Against The Spread In The NFL?

To bet against the spread in the NFL you are either betting the favorite to win by x number of points or the underdog to win, or lose by fewer than x points. For example the Chiefs -7 points or the Panthers +7 points.

The number of points is set by sportsbooks and is often referred to as the line

What Is The Best Website For NFL Picks Against The Spread?

Pickswise is the best website to get free NFL picks against the spread. Our handicappers provide free insight, analysis, and data to back up which way they’re siding against the spread for every NFL game. So far this NFL season our experts have secured 86 winning NFL picks for a profit of 26 units

Where Is The Best Place To Get NFL Picks?

Pickswise is the best place to get free expert NFL picks. We have the best cappers and NFL picks on the market and you can get all of our NFL picks for free! every week.

Each pick is meticulously researched by an experienced NFL handicapper, using our own data, custom-built models, and analytical methods. Our profit this season is 26 units and rising, so don’t miss out on the best NFL picks this week.