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College Football Parlay Picks: Saturday, November 7
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College Football Parlay Picks: Saturday, November 7

Andrew Wilsher
Andrew WilsherAuthor
UpdatedNov 7, 2026
Reading time3 min

Week 10 of the college football season promises to be the biggest, most consequential slate of the season and Saturday's card is loaded with betting opportunities. We have showcase games in nearly every conference, including a plethora of matchups between Top 25 teams that are sure to have a significant impact on the College Football Playoff picture as we hit the final month of the regular season.

Ahead of another fabulous weekend of college football, it’s time to break down our weekly CFB parlay, consisting of our expert's favorite plays of the week at +1171 odds, courtesy of Caesars Sportsbook. For more predictions and analysis, be sure to check out our CFB picks for every FBS game this year, as well as our CFB best bets for our most confident selections this week.

Minnesota ML (+165)

Syracuse ML (+116)

Missouri ML (+122)

Week 10 CFB Parlay odds: +1171

CFB Parlay Pick: Minnesota Golden Gophers ML over UCLA Bruins (+165)

On first glance, this isn’t the greatest situational spot in the world for a Minnesota team that is coming off a brutal overtime loss to Indiana last week. However, we’ve already seen PJ Fleck’s group excel in two very similar recent spots at home. Five weeks ago, the Gophers upset Michigan as a 6.5-point underdog, and followed that up with a low-scoring, grinder of a victory over Iowa as a 7.5-point underdog. We could see a similar game script on Saturday, especially in a game where the total is below 39 and continues to drop. I still don't trust the very shaky UCLA passing offense with backup quarterback Ty Dieffenbach at the controls, and it's hard to see the Bruins having much success against a rock solid Gophers defense. If Minnesota is able to load the box and take away the run in this game, the Bruins could be in real trouble in what will surely be a difficult road environment.

CFB Parlay Pick: Syracuse Orange ML over Clemson Tigers (+116)

Steve Angeli and Syracuse went into Death Valley and knocked off Clemson a season ago, and I like the Orange to take down Dabo Swinney's group once again on Saturday. This time around, Syracuse is at home and Clemson is entering this game off a pretty misleading road win over Florida State — a game in which the Tigers benefited massively from a +4 turnover margin. Things are also pretty concerning for Clemson on the injury front, with the Tigers expecting to be without their top running back, wide receiver and two pieces on the offensive line. Conversely, Angeli is getting a bit healthier after missing some time earlier in the season, and that bodes well for the Syracuse offense. The Orange have fared very well as a home underdog under Fran Brown and that trend should continue against a Clemson side that is a bit inflated in the market at the moment.

Don't miss our expert's full Clemson vs Syracuse prediction

CFB Parlay Pick: Missouri Tigers ML over Texas Longhorns (+122)

For the final leg of our parlay, we'll go to the SEC for an important showdown between Texas and Missouri. Despite the abundance of talent across the entirety of its roster, Texas is pretty fortunate to only have two losses at this point, especially when factoring in the miraculous win over Ohio State in September. Now, the Longhorns are hitting the road to play a Missouri team that is getting healthy at the right time while Steve Sarkisian’s group battles through a plethora of injuries at a number of key positions. Texas is expected to be without important pieces on the offensive line, and the Longhorns could be down multiple wide receivers as well, which doesn’t bode well for Arch Manning against this excellent Missouri pass rush. In its two games away from home this season, Texas barely squeaked by Tennessee and lost to Oklahoma. With that in mind, Missouri is certainly live to spring the upset in this one.

Grab our expert's full Texas vs Missouri prediction