Atlanta Braves vs Washington Nationals Prediction, Odds and Picks for Today, 04/22/26

Game 3 of the 4-game set between the Atlanta Braves and the Washington Nationals will be played on Wednesday night. These teams split the first 2 games with one win apiece. In each of the wins, it was a convincing victory each time. Due to the pitching matchup we have in this contest, I think we could see another lopsided victory.

The Braves will be sending Martin Perez to the mound, and he has been stellar in his first 4 outings. He has a 2.21 ERA in 20.1 innings and has only given up 5 earned runs. The Nationals will be handing the ball to Zack Littell. He has a 7.11 ERA in 19.0 innings this season, and he was tagged for eight earned runs on 11 hits in his last start. Going up against this explosive Braves offense that is averaging the second-most runs per game this season with 5.7 is not what Littell needs to see. To make things worse, in a limited sample size, many of the Braves batters have good numbers against Littell. I anticipate a similar lopsided victory in favor of the Braves on Wednesday. Give me Atlanta to cover the run line in this one.

Braves vs Nationals prediction: Atlanta -1.5 (+115) available at time of publishing. Playable at that number.

If you’re looking for a new sportsbook, we recommend checking out Fanatics Sportsbook. New users can get $200 in FanCash INSTANTLY after making their first $20 bet, no matter what! Join Fanatics Sportsbook, where you can bet on our Braves vs Nationals predictions.