Chicago Cubs vs Texas Rangers Prediction, Odds and Picks for Today, 05/10/26

The Chicago Cubs suffered their first loss this month last night against the Texas Rangers, snapping a 10-game winning streak. Now, the Cubs will look to bounce back and secure a series win behind Jameson Taillon, who is 2-1 with a 4.24 ERA through 7 starts. For the Rangers, Jacob deGrom will get the nod at 2-2 with a 3.11 ERA. DeGrom is coming off back-to-back losses, both against the Yankees, in which he allowed 7 runs on 10 hits in 12.1 innings pitched. 

DeGrom will need to be sharp against this Cubs lineup, as Chicago has been one of the best offensive teams in the league this year. Chicago enters with a .774 OPS while averaging 5.4 runs per game — making them a dangerous matchup for any pitcher. For the Rangers, they’re not as dangerous at the plate as Chicago, entering with a .686 OPS while averaging 3.7 runs.

The Rangers definitely have the advantage on the mound with deGrom compared to Taillon, but the Cubs have been the hottest team in baseball over the last 2 weeks. Look for the Cubs to score a few runs against deGrom, while Taillon holds his own on the mound — helping his team pick up the win on the road as a slight underdog.

Cubs vs Rangers prediction: Chicago Cubs ML (+110) at time of publishing. Playable up to +125. 

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