Detroit Tigers vs Chicago White Sox Prediction, Odds and Picks for Today, 05/29/26

The Detroit Tigers and Chicago White Sox are set for an AL Central battle on Friday night at Rate Field. In a pitching matchup between Detroit’s Troy Melton and Chicago’s Erick Fedde, this has the makings of a high-scoring affair. The Tiger pitching staff has been dealing with a high number of injuries all season long, and Melton is no exception. He started the season on the IL and will be making just his 2nd start of the season in this contest. He was fine in his first outing last week against Baltimore, as he allowed just a single earned run on 2 hits over 5.2 innings of work. However, the White Sox offense is rolling right now with 21 runs over their last 2 games, and there are still some question marks around Melton at this point in time. Plus, the Detroit bullpen is extremely short-handed and untrustworthy.

The White Sox will hand the ball to Fedde, who enters this matchup with a 5.47 ERA through 10 starts. Opponents have had little trouble against him through 2 months of the season. Specifically, opposing hitters are hitting a strong .272 with an OPS of .845 against the 33-year-old right-hander through 49.1 innings. The Detroit lineup hasn’t exactly been thriving lately, but Fedde’s struggles could be what the Tigers need to put forth a quality night at the plate. With a total of 8.5, look to the over.

Tigers vs White Sox prediction: Over 8.5 (+100) available at time of publishing. Playable to that number.