Houston Astros

Houston Astros vs Baltimore Orioles Prediction, Odds and Game 1 Picks for Today, 04/30/26

Oriole Park at Camden YardsMASN, SCHN
Astros
11-19
Astros
Today
Orioles
14-15
Orioles

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Baltimore Orioles
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Astros vs Orioles Pickswise Expert Predictions

Game Totals Pick
Over 9.0 (Game 1)(-110)

The Houston Astros and Baltimore Orioles get back in action on Thursday afternoon after Wednesday’s game was postponed due to weather. The teams will play a doubleheader on Thursday, with the first game pitting Lance McCullers Jr. vs. Chris Bassitt. Baltimore took the first game of the series on Tuesday by a score of 5-3.

McCullers Jr. has been in the middle of an especially poor stretch of play, allowing 15 earned runs over his last 14.1 innings. The righty has a 6.75 ERA, but his 4.94 xERA suggests that his performances should start coming back around soon. That said, the Orioles are going to be a tough matchup for that to start happening, as Baltimore has a .324 wOBA, putting them 8th-best in the majors in that category.

Bassitt allowed 10 earned runs over his first 2 starts, giving Baltimore a little bit of buyer’s remorse after stealing him from their AL East foes. Nevertheless, he bounced back as he has done in the past, going 2 games with just 1 earned run. Instead of building on it, Bassitt had another tough outing in his last start, allowing 8 hits and 5 earned runs over 5.1 innings.

The Astros have the worst bullpen ERA in the league, and the Orioles are also in the bottom half. It’ll be all hands on deck in the bullpen with Wednesday’s game postponed, but be aware that the teams may need to save some of their leverage arms for the second game.

Astros vs Orioles Game 1 prediction: Over 9 (-110) available at time of publishing. Playable at that number. 

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Nathanial Duffett

NHL and MLB handicapper for Pickswise.
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