HomeMLBMLB PredictionsHouston Astros vs Seattle Mariners Prediction, Odds and Picks

Houston Astros vs Seattle Mariners Prediction, Odds and Picks for Wednesday, 09/27/23

Updated: 6:00 AM ET Sep 28, 2023

Safeco FieldROOTNW

86-72

Astros

9:40 PM ETWed Sep 27

85-72

Mariners

Javan Shouey

Updated: 6:00 AM ET September 28, 2023

Show Bio

A lifelong sports fan from Northwestern Pennsylvania. Die-hard supporter of the Steelers, Pirates and Cavaliers. Insane passion for writing about sports and helping others improve. Incredibly thankful for the platform Pickswise is giving me. For Javan Shouey media enquiries, please email contact@pickswise.com.

MLB Analysis

See All MLB News

Milwaukee Brewers starting pitcher Jacob Misiorowski (32) celebrates striking out a batter in the fifth inning against the Minnesota Twins at Target Field.

MLB Picks Today: Expert Predictions & Best Bets for Sunday, May 31 - Jacob Misiorowski Keeps Rolling

Baseball has the stage on Sunday with a full slate of entertaining matchups. There are 3 best bets that stand out to me on this card, so let's dive right in and discuss. Looking for more action? D...

MLBPosted 1 day ago

MLB Picks Today: Expert Predictions & Best Bets for Saturday, May 30, including Cubs vs Cardinals

MLBPosted 2 days ago

Atlanta Braves right fielder Ronald Acuna Jr. (13) hits a double against the Washington Nationals in the fifth inning at Truist Park.

MLB Picks Today: Expert Predictions & Best Bets for Friday, May 29 - Nick Martinez Continues to Roll

MLBPosted 3 days ago

San Diego Padres starting pitcher Michael King (34) delivers during the first inning against the San Francisco Giants at Petco Park.

MLB Picks Today: Expert Predictions & Best Bets for Sunday, May 24 - Michael King Leads Padres to Win

MLBPosted 1 week ago

Ohio BonusesSee All

Latest Promo Codes

#1
Get Data-Driven Premium Picks Direct to Your Inbox!
Data-driven picks, best bets, parlays, and more delivered DAILY. Sign up now for access!
CLAIM NOW
#2
Polymarket is LIVE: Get a $50 Trading Bonus!
CLAIM NOW
#3
Bet $100, Get $400 in Bonus Bets
CLAIM NOW

#4
Get a $50 BetMGM Reward Points Bonus + up to $1500 Back if You Don't Win
CLAIM NOW
#5
Bet $1, Double Your Winnings for your Next 10 Wagers
CLAIM NOW
#6
Bet $5, Get $150 if Your Bet Wins!
CLAIM NOW
#7
Spend $5, Get $200 in Bonus Bets Instantly!
CLAIM NOW
#8
Spend $5, Get $50 in Novig Coins
CLAIM NOW
#9
FREE $20 - No Deposit Required!
CLAIM NOW
#10
Get $10 FREE on Sign Up With Code PICKSWISE – No Deposit Needed
CLAIM NOW
#11
Purchase $15, Get $30 in Bonus Bets
CLAIM NOW
#12
Two No Sweat Entries, up to $200 Bonus Back + A Free Pick
CLAIM NOW
#13
Get a $100 Deposit Match with Parlay Play!
CLAIM NOW
#14
Play Now on Underdog
CLAIM NOW

T&Cs apply. 21+ Gambling problem? Call 1-800-GAMBLER