Milwaukee Brewers vs Houston Astros Prediction, Odds and Picks for Today, 05/29/26

The Houston Astros host the Milwaukee Brewers this weekend for an interleague series. Both teams come in hot, winners of 7 of their last 10 games. The Brewers have been doing this all season, and they just swept the division rival Cardinals this week. The Astros have only gotten hot recently after struggling in the early part of the season. They took 2 of 3 from the Rangers earlier this week, and they were also part of the massive Cubs losing streak. We have some relatively unknown arms on the mound on Friday, which makes this game a bit harder to predict, but I am going with the homestandings Astros on the Money Line. As of the time of this writing, that can be nabbed at even money.

The Brewers will turn to Coleman Crow on Friday. He will step into the rotation spot vacated by the injured Logan Henderson. Crow has made 2 spot starts for the Brew Crew, both of them effective enough, even if only 5 innings. He will face Kai-Wei Teng, who has recently joined the rotation, which is not a 6-man situation. Teng has yet to allow a run in his 2 starts, spanning 11 innings. After the starters are gone, Milwaukee certainly had the bullpen advantage, as the Astros have the worst bullpen ERA in the league. Still, they have shown some signs of improvement lately, and the Houston offense has been hitting well. Call it a hunch, but I like the Astros tonight.

Brewers vs Astros Prediction: Astros ML (+100) available at the time of publishing. Playable to -110.