Minnesota Twins vs New York Mets Prediction, Odds and Picks for Today, 04/23/26

I favor the Minnesota Twins over the New York Mets Thursday evening, as I like the matchup for Twins starting pitcher Joe Ryan. Ryan enters this game in terrific form, and in his past matchups with active Mets batters, he has found tremendous success. Active Mets have 69 combined plate appearances against Ryan with just a .398 OPS as well as 32 strikeouts. Meanwhile, Ryan enters this start with a 3.2 ERA and 0.88 WHIP. Advanced metrics — 2.66 xERA and a 2.45 FIP — suggest he’s even better than his ERA shows, and he is fresh off of back-to-back quality starts against the Blue Jays and Reds.

Christian Scott is set to make his season debut in this game for the Mets. Scott made 9 starts with the Mets last season, totaling 47.1 innings of work in that stretch. His 4.56 ERA was shadowed by a 4.22 xERA and 4.60 FIP — a solid profile. Scott didn’t generate overwhelming strikeout numbers in his first MLB stint despite that being a large part of his minor-league success. So far this season in AAA, Scott tossed 13.2 innings across 3 starts, tallying a 5.27 ERA and 4.65 FIP. While he is clearly a talented prospect, I am not going to back him at current pricing against Joe Ryan.

Twins vs Mets prediction: Minnesota Twins ML (-120) available at time of publishing. Playable to -125 odds.

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