Minnesota Twins vs Pittsburgh Pirates Prediction, Odds and Picks for Today, 05/29/26

The Minnesota Twins head to Pittsburgh Friday night to open a three-game series against the Pittsburgh Pirates. The Twins have won six of their last 10 games, and in that span, they’re averaging 3.9 runs per game and hitting .230. For the Pirates, they’ve won five of their last 10, averaging 4.7 runs per game and batting .262. 

The Pirates will welcome back Jared Jones, who is set to make his first start in the majors since September 2024 after missing all of last season recovering from internal brace elbow surgery.  In his rookie season back in 2024, he went 6-8 with a 4.14 ERA, and struck out 132 in 121.2 innings pitched. For the Twins, Taj Bradley will take the mound, entering with a 5-1 record and a 2.77 ERA. While Bradley has been the more reliable starter overall, Minnesota’s offense continues to be inconsistent, and the Twins bullpen has struggled all season with a 4.81 ERA. Pittsburgh enters this matchup with the hotter lineup, and Jones appears fully healthy based on his rehab starts where he had an impressive 2.89 ERA with 24 strikeouts in 18.2 innings pitched. Jones comes into this game showing his velocity is still there, but he also took the time to improve his breaking and offspeed pitches. I’m expecting Jones to settle in nicely and deliver a strong pitching performance for the Pirates as they pick up a win at home. 

Twins vs Pirates prediction: Pirates ML  (-135) at the time of publishing. Playable up to – 145.