St. Louis Cardinals vs The Athletics Prediction, Odds and Picks for Today, 05/14/26

The St. Louis Cardinals and Athletics wrap up their 3-game series Thursday afternoon after the A’s picked up a 6-2 win last night. Both teams finished with 13 hits, but the difference came in the 4th inning when Nick Kurtz launched a grand slam to help the A’s pull away. Looking to secure the series victory, St. Louis will hand the ball to Michael McGreevy, who enters 3-2 with a 2.18 ERA and 0.86 WHIP while striking out 33 batters across 45.1 innings pitched. The A’s will counter with Jacob Lopez, who has struggled from time to time this year –illustrated by 3-2 record, 6.11 ERA, a 1.75 WHIP and just 28 strikeouts in 35.1 innings.

The A’s have been the stronger offensive team of late, averaging 5.0 runs per game with a .775 OPS in their last 10, compared to the Cardinals at 3.2 and .623, respectively. The A’s also added exciting young prospect in Henry Bolte to the lineup, and he made an immediate impact yesterday by going 2-for-2 with a walk and an RBI. Bolte was one of the Pacific Coast League’s hottest hitters through the first month, batting .348 with 12 home runs and 17 stolen bases across 177 plate appearances.

While Bolte is a terrific addition to this A’s lineup, I’m still concerned about Lopez taking the mound. The lefty hasn’t been great this season, while McGreevy is dealing — tossing 12 scoreless innings and striking out 12 in his last 2 starts. The A’s may have the most powerful lineup, but I like the Cardinals in this spot given the early pitching matchup. Neither team has a strong bullpen, and with the Cardinals having the edge on the mound to start the game, I think they’ll be able to separate early and earn the win.

Cardinals vs Athletics prediction: St. Louis Cardinals ML (-105) at the time of publishing. Playable up to -125.

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