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College football betting guide: Expert 2022 Week 6 college football picks, predictions, odds & best bets

College football betting guide: Expert 2022 Week 6 college football picks, predictions, odds & best bets

Andrew Wilsher
Andrew WilsherAuthor
UpdatedSep 15, 2026
Reading time1 min

Welcome to the Pickswise college football Week 6 betting guide. Our experts have done the research so that you have everything you need to hopefully beat your bookie and bet better! This is your one-stop shop for all the information for your CFB wagering on Saturday.

College football Week 6 picks

NCAAF Week 6 betting picks and predictions

College football Week 6 big-game predictions

  • Michigan vs Indiana predictions
  • TCU vs Kansas predictions
  • Texas vs Oklahoma predictions
  • Tennessee vs LSU predictions
  • Auburn vs Georgia predictions
  • Texas Tech vs Oklahoma State predictions
  • Utah vs UCLA predictions
  • Ole Miss vs Vanderbilt predictions
  • Ohio State vs Michigan State predictions
  • BYU vs Notre Dame predictions
  • Clemson vs Boston College predictions
  • Iowa vs Illinois predictions
  • Kansas State vs Iowa State predictions
  • Washington State vs USC predictions
  • Florida State vs NC State predictions
  • Texas A&M vs Alabama predictions

Pickswise is the home of College Football Picks and College Football Predictions. Check out our latest College Football analysis including our College Football Parlay picks and our College Football Best Bets.