NFL betting guide: Expert 2022 Week 15 NFL picks, predictions, odds & best bets

Cincinnati Bengals quarterback Joe Burrow (9) hands the ball off to Cincinnati Bengals running back Joe Mixon (28) in the third quarter during a Week 3 NFL football game, Sunday, Sept. 26, 2021
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Phil Agius

NFL

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I've been writing about the NFL and a host of other sports for the UK's top daily betting paper the Racing Post for more than 20 years. An incurable Browns fan (1-31 survivor), I also specialise in all kinds of motorsport betting including F1, MotoGP, IndyCar and NASCAR. For Phil Agius media enquiries, please email contact@pickswise.com.
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Welcome to the Pickswise NFL Week 15 betting guide! Bye weeks have waved a belated goodbye and it’s full steam ahead for the decisive weeks of the regular season. The 49ers became the first team to be crowned divisional champions this season with Thursday’s NFC West win over Seattle and the pre-Christmas schedule also treated us to a 3-game Saturday slate.

There is still plenty of great action to look forward to on Sunday, however, with the 1:00pm ET games including Cowboys vs Jaguars and Lions vs Jets, with Zach Wilson back at the controls of the New York offense. The later afternoon games include Bengals vs Buccaneers, Patriots vs Raiders and Titans vs Chargers before the Giants visit the Commanders on Sunday Night Football.

Our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL Sunday — and for Monday night’s Rams vs Packers game. Don’t forget to check out our great NFL predictions for every game on the Week 15 slate.

NFL Week 15 picks

  • NFL picks against the spread and total for EVERY Week 15 game – we went 11-2 on sides in Week 14!
  • NFL best bets – we have a 45-30 record on our 3-star plays this season 
  • NFL parlays

NFL Week 15 expert betting picks and predictions

NFL Week 15 prop bets

NFL Week 15 Promo Codes

Find all the latest Sportsbook Promo Codes and Bonuses for NFL Week 15, including sportsbooks live in your state.

NFL Week 15 big-game predictions

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