NFL betting guide: Expert Week 16 NFL picks, predictions, odds & best bets
Welcome to Week 16 of the NFL season. Our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL weekend. You can also read our great NFL predictions for every game on the Week 16 slate.
NFL Week 16 picks
- NFL picks against the spread and total for EVERY Week 16 game
- NFL best bets
- NFL parlays
NFL Week 16 expert betting picks and predictions
- Pickswise experts’ best bets
- NFL Week 16 mega parlay (+1671 odds)
- Patriots vs Broncos Same Game Parlay (+716 odds)
NFL Week 16 prop bets
NFL Week 16 big-game predictions
- Cleveland Browns vs Houston Texans predictions
- Detroit Lions vs Minnesota Vikings predictions
- Dallas Cowboys vs Miami Dolphins predictions
- New England Patriots vs Denver Broncos predictions
- Las Vegas Raiders vs Kansas City Chiefs predictions
- Baltimore Ravens vs San Francisco 49ers predictions
