Wise n' Shine: MLB picks and golf predictions for Wednesday, September 21

Good morning Pickswise Nation and welcome to another day of sports! Unfortunately, we are still without football, but we do have a full MLB slate today, so let’s get straight to making your next bet better!

About Last Night

YRFI/NRFI bets stay HOT
Our streak continued to 6-0 last night as our YRFI/NRFI picks once again went 2-0. A scoreless first frame in Miami and Oakland extended our streak another day, and don’t worry, today’s YRFI/NRFI picks are already live. Also around the diamond on Tuesday, Aaron Judge hit his 60th home run of the season as the Yankees mounted an incredible comeback in the 9th inning that was capped off by a walk-off grand slam by Giancarlo Stanton.

Today’s Slate

A full day of MLB
Another full slate of Major League Baseball is in store on Wednesday as division and Wild Card races are becoming incredibly close, so matchups such as the Guardians-White Sox, Mets-Brewers and Astros-Rays have extra importance. You can read our MLB picks for all of today’s games.

Best Bet of the Day

MLB: Cleveland Guardians vs Chicago White Sox under 7.5 runs
8:10 pm ET

Triston McKenzie has been stellar against the White Sox all season, and with Lance Lynn’s second-half surge, I anticipate this to be a low-scoring game. Lynn’s last start against the Guardians finished with 10 runs, but that was with Hunter Gaddis on the mound for Cleveland. McKenzie is a much more talented pitcher than Gaddis, who has only made 2 MLB starts, so the first half of the game should be very low scoring. That should be the same for the second half as Cleveland’s bullpen has been very consistent since the all-star break, and the White Sox bullpen has been surging in the last few weeks. This pitching matchup makes for a great game and a low scoring one. Check out our full Guardians vs White Sox predictions.


As mentioned above, our YRFI/NRFI bets are incredibly hot right now. You can find today’s YRFI/NRFI best bets here, so don’t miss out! We also have our +1138 MLB mega parlay available, so check that out too!

After hitting another winner with Max Homa over the weekend, Pickswise golf analyst Diane Knox Balas is back with her picks and best bets for the Presidents Cup. The action starts on Thursday so make sure you get the most value on your picks by checking out her tips!

Thursday Night Football isn’t for another day, but our prop expert already has his Steelers vs Browns best player props and our Pittsburgh vs Cleveland same game parlay is live as well!

Keep an eye out for more great sports analysis as it arrives throughout the day on the Analysis tab.


Don’t forget to check out our daily show Let’s Bet It on our YouTube channel at youtube.com/c/Pickswise at 10:00 am ET.

Lauren Jbara & Jared Smith are your hosts today and they will be joined by Diane Knox Balas, our very own Pickswise golf expert. The trio will discuss the Presidents Cup, while Lauren and Jared will assess the NFL Week 3 line movement, the key matchups in College Football and give their Plays of the Day!

You can also access the show at any time through Spotify and Apple Podcasts (search for Let’s Bet It Presented By Pickswise).

Stat of the Day

Following his home run last night, Aaron Judge now leads the American League in batting average, RBIs and home runs.

Pickswise is the home of free sports picks, news and best bets. Check out our expert NFL Picks, NBA Picks, MLB Picks and NHL Picks pages for our latest game Picks.

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