NFL Picks

NFL picks for every game of the 2025-26 season. Our NFL expert picks are informed by key betting trends, statistical analysis and years of NFL betting experience. +21.7 units of profit, from 105 winning ATS picks so far this season is the proof.

Our NFL picks this week include against the spread picks for every game in week 14, highlighted by Cowboys vs Lions on Thursday Football, Texans vs Chiefs on Sunday Night Football and Eagles vs Chargers on Monday Night Football.

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Point Spread Pick

LA Chargers +3.0(-110)

Reasoning

As if losing to the Cowboys in Week 12 wasn’t enough, Philadelphia followed that up with a home loss to the Bears this past Friday. In the process, they looked worse than they have all season. Generating just 6.2 yards per play and converting just 4 out of 12 third downs, another lackluster performance by Saquon Barkley juxtaposed 2 turnovers from Jalen Hurts, who went just 19-34 for 230 yards. Even more startling, the Eagles possessed the ball for only 20 minutes and 42 seconds, just one-third of total game-time.

Perhaps even more surprising was their defense, a group that had been holding up their roster for weeks on end and finally capitulated. The Bears ran it down their throat for all 4 quarters, gaining 281 yards on the ground and 425 total. Chicago correspondingly gained 28 first downs, doubling Philadelphia. Radio personalities in the City of Brotherly Love are anything but loving after that performance, and the Eagles are now a main topic of discussion in the national media. It all feels very 2023, a season where the Eagles completely sputtered at the end of the year, losing 5 of their last 6 games. We wouldn’t be surprised if the exact same thing happened here. Without a formidable rushing attack and top-tier play-calling, Hurts is not the kind of quarterback who can carry his team.

The Chargers had an easy breezy win in Week 13, blowing by the Raiders at home. Beating up on Vegas is hardly an indication of a return to top-form for any program, but it was a nice response after their bye-week. Defensively they’re still among the best, 7th overall in defensive EPA. Offensively LAC remains a middling program, ranked 16th in offensive EPA, and now they’re concerned for Justin Herbert. He had surgery on his left hand on Monday and he’s considered day-to-day. In general, the Chargers have played poorly against great teams, but we can hardly consider the Eagles “great” at this juncture.

The Monday night total is very low and the spread indicates this will probably be a close game. The combination suggests neither offense will pull away, which is largely what we’ve seen this season. The Bolts don’t have much of a home-field advantage, but the ability to stay home for a full week and rest before a big opponent is surely preferable. Meanwhile, Philadelphia will travel across the country and experience the lag of a 3-hour time difference. The Chargers could easily be the favorite in this game, so we have no other choice.

Eagles vs Chargers MNF prediction: Los Angeles Chargers +3 (-110) available at time of publishing. Playable to 2.

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Game Totals Pick

Under 40.5(-110)

Reasoning

A very low total is very appropriate for these struggling offenses. We’ll start with the Eagles, although their transgressions are well documented at this point.

After a fast 4-0 start, Philly’s production has slowed down mightily. Since Week 5, they’ve only eclipsed 340 yards in 2 out of 8 contests, and rarely do they have a big game on the ground. Saquon Barkley and his backfield teammates just don’t produce much, good for only 4 yards per carry (24th). Since Week 5, they’ve only eclipsed the century mark 3 times.

That puts a ton of pressure on Jalen Hurts, who’s not built for such a role. We’re not suggesting he hasn’t done great things, but year after year Philly has endured turnover in offensive coordinators, a result that’s finally starting to affect them. Kevin Patullo, who has limited experience in the role, is certainly starting to show his naivete. Philadelphia’s offense ranks just 14th in total EPA, and on Monday they’ll be combating one of the NFL’s best defenses.

The Chargers’ offense isn’t exactly prolific, either. A burgeoning rushing attack has helped keep them afloat. If you take out a very poor all-around outing at Jacksonville back in Week 11, the Chargers ran for 645 yards in their past 4 games. Justin Herbert’s surgery on his non-throwing hand is cause for concern, but LAC’s passing attack hasn’t been stellar either way. They rank 18th in EPA per pass and average 7.2 yards per pass (14th), but lately it’s regressed further. In his last 5 starts, Herbert has thrown for 212, 212, 199, 93, and 149. Woof.

This has “old-school defensive battle” written all over it.

Eagles vs Chargers pick: Under 40.5 (-110) available at time of publishing. Playable to 40.

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Chris R. Farley

Same Game Parlay Pick

O. Hampton (LAC) 40+ & S. Barkley (PHI) 60+ rush yds(+144)

Reasoning

Nick Sirianni has taken over play-calling for the Eagles this week after much has been made about the stale offense of late. For me, I interpret that as a big dose of Saquon Barkley that will open up opportunities for Jalen Hurts in the passing game. On the Chargers’ side, Omarion Hampton’s injury really exposed some inadequacies in the Chargers’ offense, and even though Herbert’s injury is to his non-throwing hand, it’s better to limit his dropbacks when possible.

The total sitting at 42.5 tells me that the game script should lend itself to a battle of the running backs and a key stat on 3rd down is putting me over the edge here — both Philadelphia and Los Angeles are bottom 12 in the league on rushing first downs over the last 3 weeks. These are situations where the rush is obvious, and the defenses were unable to come up with the stop. I’m going to lean on these 2 starting RBs having a big role in a low-scoring affair.

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Bobby Stanley Jr. (PropHolliday)

Anytime Touchdown Scorer Pick

AJ Brown (PHI) to score a TD(+190)

Reasoning

It’s been a rollercoaster of a season for AJ Brown and the Philadelphia Eagles. Brown struggled amidst the Eagles’ 8-2 start to 2025. Yet, over the last 3 games, 2 being losses to the Cowboys and Bears, Brown has led the league in first-read targets. The Eagles have made an effort to get their #1 receiver the ball, especially in the red zone. During those 3 weeks, Brown has 4 receptions inside the 20-yard line, which ranks inside the top 5 in the NFL. Look for Jalen Hurts to hunt down Brown against a Chargers defense that runs zone at an 82% rate — the 2nd-most in the NFL.

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Anytime Touchdown Scorer Pick

L. McConkey (LAC) to score a TD(+250)

Reasoning

The status of Justin Herbert is still in question heading into Monday Night Football. If he does play, you’d expect him to operate in the shotgun with a hand injury as severe as his. Quick hitters to Ladd McConkey and Keenan Allen may be Herbert’s best bet for MNF — especially against a talented Eagles defensive front.

Last week was the Kimani Vidal show against the Raiders, which featured a positive game script. I don’t anticipate another 25 combined carries from Vidal and Omarion Hampton, who is returning from an IR stint, even with Herbert’s injury. So, we’ll turn to McConkey as our 2nd Eagles vs Chargers TD scorer bet, who has found the end zone 5 times in his last 8 games.

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Justin Martin (JutPicks)

Same Game Parlay

Money Line

LA Chargers Win

Anytime Touchdown Scorer

O. Hampton (LAC) to score a TD

Anytime Touchdown Scorer

S. Barkley (PHI) to score a TD

Reasoning

LA Chargers ML over Philadelphia Eagles (+120)

It’s starting to feel like the 2nd half of the 2023 season, which went entirely off the rails for Philadelphia. We certainly haven’t reached that point quite yet in 2025, but things are starting to go haywire. The Eagles will still probably win their division because nobody else is any good, but the bottom line is that they aren’t playing well. Even prior to their current 2-game skid, the Birds scored a combined 26 points in unceremonious victories over Green Bay and Detroit. Saquon Barkley is not doing much of anything, Jalen Hurts is struggling and AJ Brown is disgruntled. It’s simply impossible to have any faith in this offense.

Los Angeles had been dealing with its own problems on that side of the ball, but the offensive line is getting healthier and Hampton has recovered from his ankle issue. He immediately gets to face a Philly defense that got run all over by Chicago on Black Friday. Assuming that Justin Herbert will be under center despite a hand injury (non-throwing), LA has great value as an underdog. A home game against an opponent from 3 time zones away will only help the Bolts’ chances.

Omarion Hampton to score a touchdown (+165)

Hampton is finally back from his ankle injury and will play for the first time since Week 5. Before going down, the rookie out of North Carolina had 66 carries for 314 yards and 2 touchdowns in addition to 136 receiving yards. Hampton, a first-round selection, was coming up big for the Chargers. He should pick up right where he left off given that he has a favorable matchup on MNF.

The Eagles‘ defense has not been great against the run all season long and was especially poor in that department against the Bears. Philly has surrendered 14 touchdowns on the ground – even more than its 12 passing TDs allowed. In fact, both the Eagles and Chargers are 2 of only 3 teams in the entire NFL who have given up more rushing touchdowns than passing.

Saquon Barkley to score a touchdown (+110)

It’s probably time to give up on Barkley ever turning in the type of huge performances that he delivered so many times during the 2024 campaign. However, asking him to simply get into the end zone on Monday Night Football should not be too much. As mentioned above, the Bolts also allow an unusual number of scores on the ground – 14, compared to 12 through the air. Although Barkley has underwhelmed for the most part this year, he has still produced a respectable 6 TDs (4 rushing, 2 receiving).

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Vote on who will win!

Why Trust our NFL Picks

Through week 13 of the 2025 season our team of NFL handicappers have made against the spread and totals picks for every game. with 105 wins (and 2 pushes) our record speaks for itself. Our expert NFL picks against the spread have scored +21.7 units of profit so far this season.

Wins	Push	Losses	Profit (betting units)
105	2	85	+21.7

At Pickswise, every NFL pick is backed by years of betting experience, advanced data analysis, and a proven track record of success. Our team of handicappers studies line movement, injury reports, historical trends, and matchup stats to deliver informed recommendations — not guesses. We publish our results openly, update our predictions as new information emerges, and never hide behind vague analysis. Whether you’re looking for expert spreads, totals, props, or parlays, our mission is simple: give you honest, well-researched picks that stand up over time.

Free NFL Picks Explained

We firmly believe expert NFL picks should be free, so you’ll find our NFL picks today, and every day of the season, right here. We publish our free NFL picks for every game, at least a few days in advance of gameday, so you know who the experts are backing without missing out on the early value in the betting markets.

There’s almost an infinite way to bet on the NFL, from NFL picks against the spread, moneyline, over/under, NFL Parlays, and NFL Prop Bets, there is a bet type for every kind of football fan, so we provide NFL picks for every bet type. Some bettors like to specialize in a single particular type of NFL pick, while others like to have a diverse range and bet on anything they feel is a value pick.

Here at Pickswise, we have something for everyone. Our team of handicappers have a wealth of experience in making NFL picks across all these betting markets, leaving no stone unturned ahead of every game and every pick of the 2025 NFL season. If you’re looking for more information on NFL bet types, You can find our expert breakdown of each below.

NFL Picks Against the Spread

The most popular way to bet on the NFL is against the spread (ATS). With these wagers, you are not picking a simple winner or loser of a game. Instead, ATS betting is placing your money that Team A wins by a certain amount of points or that Team B will keep the game closer than oddsmakers expect, in other words, not lose by that same amount of points.

For Example

Philadelphia Eagles -7 – Philadelphia must win by 8 or more points to cover the spread.
Chicago Bears +7 – Chicago must win, or lose by 6 or fewer points to cover the spread.
Tie Scenario – If the game ended 27-20 to Philadelphia, the spread would be a tie, or a push and stakes would be returned.

NFL spread betting trends 2025

The team that covers the spread wins the game outright around 80% of the time.
Road teams going into games as the favorite have covered the spread at 64% so far this season
Teams coming off a blowout loss (20+ points) tend to rebound against the spread, 57% of the time.

Free NFL Over / Under Picks

Another exciting way to still get in on the NFL action is with totals wagers. In these bets you don’t take a side, but whether the two teams will combine to score over or under the total number of points that the oddsmakers have set. Already since sports betting has been legalized we’ve seen many occasions where a hail mary, missed FG or XP has cost over or unders bettors, so be prepared to be in for the long haul with your totals bets. We preview every game of the NFL season, providing insight into the game as a whole alongside expert NFL picks so you can make informed NFL totals bets.

NFL over / under betting trends

Overall, unders have proven the value pick in recent seasons, as defenses have caught up with scoring trending down since 2021
Unders bets have the edge in divisional games, landing 57% of the time. This trend gets stronger late in the season (week 13 onwards), especially in cold weather conditions.
Unders bets have landed on 58% of primetime games, as public betting tends to have a bias for the overs in these games.

Money Line NFL Picks

Ask any seasoned NFL bettor and they’ll tell you that ATS betting is exciting, but can also be frustrating. It is important to keep in mind that NFL teams only need to win by one, of course, they’d love to win by more, but they’ll change their schemes late on to secure a win, not to ensure they cover the spread. Your research could have given you the right side, but if they win by 6 instead of 7 your -6.5 bet is a loss. Therefore a lot of bettors like to keep it simple and take our expert NFL Money Line picks and bet on the NFL straight up.

NFL Moneyline betting trends

Through the first 4 weeks of the 2025 season 6+ point favourites have been strong straight up, with a 16-2-1 record
Short underdogs (+1 to +3 on the spread) win outright 43% of the time, offering better value on the moneyline than the spread
Underdogs in lower scoring road games (less than 42 total points) win outright 39% of the time, but often at better prices than this record suggests.

2025-26 NFL Schedule

This will be the 106th season in league history and is set to kick off with the NFL Kick-Off game on Thursday, September 4, hosted by the defending Super Bowl Champions Philadelphia Eagles, who take on the Dallas Cowboys. The regular season will come to a conclusion on January 4, 2026 with the NFL Playoffs scheduled to begin the following weekend on the 10th, 11th & 12th of January 2026. Super Bowl LX is scheduled for February 8, 2026, at Levi’s Stadium in San Francisco, California, the home of the 49ers.

NFL Playoff Picks

You can find our NFL picks for the 2026 Playoffs, right here, for free. Wildcard Weekend is scheduled to start January 10, upon the conclusion of week 18 our experts start to make their picks and predictions for the first round of the playoffs and after each round is concluded we prepare for the coming weekend, all the way up to the Super Bowl.

NFL Playoff Picks
NFL Wildcard Weekend Picks
NFL Divisional Round Picks
NFL Conference Championship Picks

NFL Expert Picks

Our NFL Football picks will be for every game throughout the regular season, with primetime games and the top matchups each week getting additional expert coverage which will extend to every playoff game. These NFL Football picks will come alongside analysis and the latest stats and trends to consider when betting. You can also find our NFL Best Bets for the top plays of the week and a confidence rating for our expert handicapper.

Looking for alternative football picks? then head to our College Football Picks page, where you’ll find the same level of expertise from the Pickswise handicapping team for all the headline games in the 2025 NCAA football season.

More Than Just NFL Football Picks

We also specialize in every major North American sport including the MLB, NBA, NHL, College Football, and College Basketball. Check out our site every day for some of the best bets in every major athletic contest and make sure to follow us on social media as well.

Andrew Wilsher, Managing Editor of Pickswise

Statistical Approach to NFL Picks

It’s our goal to provide you with the best NFL picks in the market. Our expert handicappers are all specially selected and assessed prior to joining the team to ensure their analysis. experience and results are among the best in the industry. Each capper will put hours of research into each pick and many have built statistical models to find their moneyline, spread and over/under picks so you don’t have to. Check out all of our cappers’ free NFL picks here every week of the season.

Andrew Wilsher, Pickswise Managing Editor

NFL Picks FAQs

How Do You Pick Against The Spread In The NFL?

To bet against the spread in the NFL you are either betting the favorite to win by x number of points or the underdog to win, or lose by fewer than x points. For example the Chiefs -7 points or the Panthers +7 points.

The number of points is set by sportsbooks and is often referred to as the line

What Is The Best Website For NFL Picks Against The Spread?

Pickswise is the best website to get free NFL picks against the spread. Our handicappers provide free insight, analysis, and data to back up which way they’re siding against the spread for every NFL game. So far this NFL season our experts have secured 86 winning NFL picks for a profit of 26 units

Where Is The Best Place To Get NFL Picks?

Pickswise is the best place to get free expert NFL picks. We have the best cappers and NFL picks on the market and you can get all of our NFL picks for free! every week.

Each pick is meticulously researched by an experienced NFL handicapper, using our own data, custom-built models, and analytical methods. Our profit this season is 26 units and rising, so don’t miss out on the best NFL picks this week.