NFL Picks

NFL picks for every game of the 2025-26 season. Our NFL expert picks are informed by key betting trends, statistical analysis and years of NFL betting experience. +27.4 units of profit, from 113 winning ATS picks so far this season is the proof.

Our NFL picks this week include against the spread picks for every game in week 15, highlighted by an all-NFC South Thursday Night Football when the Falcons take on the Buccaneers. Sunday Night Football will see the Vikings travel to Dallas to face the Cowboys and on Monday Night Football it’s Dolphins vs Steelers.

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8:15 PM ET
Tomorrow
Amazon Prime Video
Atlanta Falcons
Tampa Bay Buccaneers
Falcons
Buccaneers
Point Spread Pick
TB Buccaneers -4.0(-110)

Once the clear leaders of the NFC South, the Falcons and Bucs are both reeling after another bad performance. In Atlanta’s case it’s par for the course, a program lost at this point of the season. Coach Raheem Morris seems to have no true influence over his roster, either. Over the past eight weeks their only win was against the Saints, a fellow NFC South bottom feeder, and even in that matchup they were out-gained 21-13 in first downs. Kirk Cousins looked especially bad in Week 14, completing just 15-30 for 162 yards and two interceptions. The defense continues to regress as well, allowing the Seahawks to put up 31 points in the second half last Sunday. In short, there’s no good reason to trust Atlanta right now, even if the team they’re facing next is going through their own share of problems.

The Bucs dominated survivor entries and teaser-legs all over the country in Week 14 in what seemed to be an auto-play for many bettors. That didn’t go so well. The Saints showed up to compete, putting up 17 points en-route to victory in southern Florida. Baker Mayfield played as poorly as Kirk Cousins last Sunday, going 14-30 for 122 yards (4.1 yards per pass), one touchdown and one interception. The Bucs’ defense, which now ranks 14th in total EPA, eventually capitulated, but their offense is far more disappointing. Decimated by injuries, the Bucs’ offense sunk to 22nd in total EPA metrics, a sad measure considering they looked like one of the most explosive offenses early in the season. 

The good news for Tampa is that they’re getting healthier. Their best offensive lineman, Tristan Wirfs, sat out last Sunday but is trending towards suiting up on Thursday. Even better, their star wide-receiver, Mike Evans, has logged four straight practices and looks to return after missing seven weeks of action. Even without those two stalwarts, the Bucs need this win to further cement their lead in the NFC South. The Falcons are showing no signs of progression, nor do they have much to play for.

Falcons vs Buccaneers TNF prediction: Bucs -4 (-110) available at time of publishing. Playable to 5.

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Game Totals Pick
Over 44.5(-110)

The Bucs’ offense isn’t what it used to be at the start of the season but that doesn’t mean it can’t improve again. Thursday is also a good spot for positive regression. Atlanta’s defense has been spiraling for quite some time. Since Week 8 they’ve allowed 28 points per game. Four out of those seven opponents hit or eclipsed 30 points. Mike Evans is trending towards playing on Thursday, but even if he doesn’t the Falcons are officially 26th in defensive EPA per rush, permitting 4.5 yards per carry (24th). Bucky Irving has played well but has yet to make a big splash since his return in Week 13. We think this is the ideal opportunity. Baker will look to correct his transgressions from last week, too (4.4 yards per play). We expect a much better showing from the whole offense. 

On the other side, the Falcons’ defense looked lost in Week 14 and has looked lost for weeks, but the Falcons’ offense still shows flashes of its talent here and there. Kirk Cousins had one of his worst outings as a professional quarterback in Week 14. It’s likely this could be his final stretch of games as a starter in the league. If I’m Kirk and I’m battling a Bucs’ defense that hasn’t played well (Tampa is 20th in defensive EPA per pass), I’m excited to take advantage of this matchup. And it’s not like Atlanta hasn’t done well against the Bucs before. Back in Week 1, they totaled 358 yards and 23 first downs on Todd Bowles’ defense, a battle they should have won.

Both offenses are due for a better day, particularly the Bucs. On a short week and both rosters battered at this point of the season, we like both offenses to rule the day.

Falcons vs Bucs pick: Over 44.5 (-110) available at time of publishing. Playable to 45.

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1:00 PM ET
Sun Dec 14
FOX
Arizona Cardinals
Houston Texans
Cardinals
Texans
Point Spread Pick
HOU Texans -9.5(-110)

The Houston Texans will be trying to extend their winning streak to 6 games when they host the Arizona Cardinals in Week 15 of the NFL season on Sunday afternoon. Only the Patriots (10) have won more consecutive contests than the Texans. I expect that trend to continue, so my Cardinals vs Texans pick is for the home team to win and cover. Head coach DeMeco Ryans’ red-hot squad boasts an 8-5 record and has moved into AFC wild-card position — and in second place in the AFC South — ahead of Indianapolis. Houston’s defense is arguably the best in the entire league. The Texans are #1 in total defense, #1 in scoring defense, #4 against the pass and #5 against the run. Four straight opponents have stayed under 20 points, including the Bills, Colts and Chiefs.

Arizona, on the other hand, is a team in turmoil. It is 3-10 and has lost 5 games in a row. Quarterback Kyler Murray (foot) has not played since Week 5 and won’t play again this year — and probably not ever for this particular franchise. Jacoby Brissett has been solid in Murray’s absence, but this offense just isn’t dynamic. And when you are facing Houston, your offense better be electric if you want to have even a remote chance of success. On the other side of the ball, the Cardinals’ defense is 26th in scoring (26.8 ppg allowed) and their 24 sacks are among the worst in the NFL. The Cards are 1-4 against the spread in in their last 5 overall, while the Texans are 3-0 ATS in its last 3, 4-1 ATS in its last 5 on the road and 2-0 ATS in the last two head-to-head meetings

Arizona Cardinals vs Houston Texans prediction: Texans -9.5 (-110) available at time of publishing. Playable to -10.

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Game Totals PickBest Bet
Under 42.5(-108)

It’s hard to even describe just how good the Texans’ defense is. Perhaps the most telling way to say it is that the unit is so good that you might actually tune into a football game for the purpose of watching defense instead of offense. Yes, the Texans’ defense is legitimately fun to watch — and it is the main reason why my Cardinals vs Texans pick is Under 42.5. They have recorded 36 sacks and have forced 22 turnovers (fourth most in the league). Moreover, the offense has committed the third-fewest turnovers in the NFL (10) — so it rarely puts the defense in bad situations. Speaking of the offense, quarterback C.J. Stroud has been solid but unspectacular in 2 starts since missing 3 games with concussion. In those 2 appearances he went a combined 37-of-66 for 479 yards, 1 TD and 1 INT.

Meanwhile, Brissett is playing well for the Cardinals but is not getting much help at all from the running game. And no matter what Brissett brings to the table on Sunday, it’s hard to like any offense’s chances against Houston at the moment. Will Anderson Jr., Danielle Hunter and others are probably going to wreak havoc in the backfield. I’m not even entirely positive that Arizona will avoid getting shut out. The under is 4-0 in the Texans’ last four overall and 2-0 in the last two head-to-head encounters.

Arizona Cardinals vs Houston Texans prediction: Under 42.5 (-108) available at time of publishing. Playable to -40.5.

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1:00 PM ET
Sun Dec 14
FOX
Las Vegas Raiders
Philadelphia Eagles
Raiders
Eagles
Point Spread Pick
LV Raiders +11.5(-110)

The Philadelphia Eagles will be eager to halt a 3-game losing streak when they entertain the Las Vegas Raiders in Week 15 of the NFL season on Sunday afternoon. Why are the Eagles playing so poorly and showing the same signs as their second-half demise in 2023? Well, their offense is horrible right now. Since its Week 9 bye, head coach Nick Sirianni’s squad has posted 10, 16, 21, 15 and 19 points in its last 5 outings. Saquon Barkley finally heated up with 122 yards and a touchdown in Monday night’s 22-19 overtime loss to Chargers, but 52 of those yards — and the TD — came thanks to blatant hold by left tackle Jordan Mailata. Barkley now faces a Las Vegas defense that does 1 thing well: stop the run. The Raiders are holding opponents to 113.9 rushing yards per contest on 3.9 yards per carry (fifth fewest in the NFL).

Admittedly, there is not a whole lot of good to say about a 2-11 Las Vegas squad. To be exact, there are 2 bright spots on the roster. Tight end Brock Bowers comes in with 619 receiving yards and 6 touchdowns. Defensive end Maxx Crosby has 9 sacks, 25 tackles for loss, 1 interception and 2 forced fumbles. Philly is 0-3 ATS in its last 3 overall and 1-3 ATS in the last 4 head-to-head meetings. This is slightly too big of a spread for a matchup between 2 reeling offenses that could be low scoring.

Las Vegas Raiders vs Philadelphia Eagles prediction: Las Vegas +11.5 (-110) available at time of publishing. Playable at that number.

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Game Totals Pick
Under 38.5(-110)

Outside of Bowers, there is literally nothing about the Raiders’ offense that inspires any confidence — not even rookie running back Ashton Jeanty, a first-round draft pick. In fact, Las Vegas is dead last in the NFL in rushing offense by a country mile (72.7 yards per contest). Its 3.4 yards per carry are also worst in the league. Head coach Pete Carroll’s crew is last in the league in scoring (15.1 ppg) and second-to-last in total offense (257.2 yards per game). Quarterback Geno Smith has struggled all year to the tune of having almost as many INTs (14) as TDs (16). Smith is questionable for this weekend due to a shoulder injury sustained during last Sunday’s setback against Denver. Largely because of this offense, my Raiders vs Eagles pick is Under 38.5.

Of course, Philly should also contribute to a low-scoring affair. Its offense has been shockingly inept over the past 5 weeks. Jalen Hurts’ struggles actually got worse in Week 14 — and that’s an understatement. The Alabama product committed an absurd 5 turnovers against the Chargers, including 2 on 1 play alone! That’s right; he threw a pick, recovered an ensuing fumble and then fumbled it back to the Bolts. Hurts’ fourth interception of the night in overtime ended the game in unceremonious but appropriate fashion. The under is 3-1 in the Raiders’ last 4 road games and 5-0 in the Eagles’ last 5 overall. It’s a lean toward the under for me.

Las Vegas Raiders vs Philadelphia Eagles prediction: Under 38.5 (-110) available at time of publishing. Playable at that number.

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4:25 PM ET
Sun Dec 14
FOX
Carolina Panthers
New Orleans Saints
Panthers
Saints
Point Spread PickBest Bet
CAR Panthers -2.5(-115)

It will be a showdown in the NFC South when the Carolina Panthers visit the New Orleans Saints on Sunday afternoon. New Orleans did Carolina a solid by upsetting division-rival Tampa Bay in Week 14, but the Panthers won’t return the favor by playing nice this weekend. After all, they are now in the thick of a division race. The door is open for the Panthers and — at least for the time being — I expect them to walk through it. My Panthers vs Saints pick is for the visitors to win and cover. This is a fantastic spot for the visitors. Carolina is coming off a bye and facing an opponent that just picked up its biggest win of the season, thus inflating its value.

The Saints are very bad — way worse than this 2.5-point spread indicates. Their season-long sample size confirms that this is a far inferior team compared to what was on display at Tampa Bay this past weekend. The Bucs really aren’t that good, either. In fact, they have been in shambles since a hot start to the 2025 campaign — their record since a Week 9 bye is 1-4. The Saints gained only 260 yards of total offense but still managed to prevail 24-20. Now they return to the Big Easy, but their is no home-field advantage for them these days. They are 1-5 at the Mercedes-Benz Dome this season compared to 2-5 on the road. Meanwhile, the Panthers are 6-3 SU in their last 9 overall and find themselves tied atop the NFC South with the Bucs. Carolina most recently stunned the Rams in Week 13 as Bryce Young continued to heat up. Young has thrown at least 3 touchdown passes in 4 games so far in 2025.

Carolina Panthers vs New Orleans Saints prediction: Panthers -2.5 (-115) available at time of publishing. Playable to -3.

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Game Totals Pick
Under 40.5(-110)

Only 24 total points were scored in the first head-to-head matchup of this 2025 campaign. Now we’re asking Carolina and New Orleans to combine for at least 41?!?! It’s a no from me. My Panthers vs Saints pick is Under 40.5. The Saints have played 13 games this season; only 3 times have they reached the 20-point mark — and in those 3 exceptions their outputs were 21, 24 and 26 points. Despite prevailing at Tampa Bay 24-40 this past weekend, New Orleans’ offense amassed a grand total of 260 yards. Running back Alvin Kamara is a shadow of his former self and is questionable for Sunday due to a knee injury.

Somewhat surprisingly, neither defense is terrible. Carolina’s is arguably above average, while New Orleans is at least quite good against the pass — #6 in the NFL in that department. The Panthers are tied for 10th in the league with 17 takeaways and the Saints have committed the third-most turnovers with 20. It’s just hard to see this matchup developing into a high-scoring or even medium-scoring affair. Something along the lines of their first head-to-head encounter is far more likely.

Carolina Panthers vs New Orleans Saints prediction: Under 40.5 (-110) available at time of publishing. Playable to 39.5.

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8:20 PM ET
Sun Dec 14
NBC
Minnesota Vikings
Dallas Cowboys
Vikings
Cowboys
Point Spread Pick
MIN Vikings +5.5(-110)

The mystical JJ McCarthy experience continues. In Week 14 it was the good kind. Needless to say, NFL media and Vikings’ fans were losing trust in Kevin O’Connell before last Sunday, the guy who orchestrated Sam Darnold’s departure and put his stock in the former Michigan star. Many are still very skeptical, including yours truly. JJ McCarthy had enough good moments in his initial few starts to suggest maybe there’s something there, including a sterling fourth quarter comeback against the Bears in Week 1. But until last week most of his performances were of the bad kind, reminiscent of a kid whose confidence may have overshot reality. Last week the good version returned for at least one game, even if the rookie got a lot of help from his teammates. Minnesota jumped out to a 14-0 lead after their first two drives. The second drive was a brilliantly executed, 12 minute, 98-yard showcase of O’Connell’s ability to design the perfect offense for any quarterback. But the Vikings only gained 42 yards for the next two quarters following. In garbage time eventually capitalized on a few advantageous short fields. While we were mildly impressed by McCarthy in Week 14 (16-23, 163 yards, three touchdowns and no interceptions), it doesn’t mean their offense is suddenly “figured out” again, nor do we trust the rookie to perform consistently at that level. 

Minnesota’s defense is less of a concern, 9th overall in total in defensive EPA and most weeks keeping their team in the game. They’ll need to be one of the best this Sunday.

The Dallas offense tripped up this past Thursday against the Lions, but we’re not going to fade the Cowboys because of one game. Week 14 was more about their opponent, a desperate team at home who rode momentum once they found it. Dallas’ offense still had its chances, and Detroit struggled limiting their production throughout the contest (417 total yards, 25 first downs, both out-pacing Detroit). Regardless, Dallas retains a top unit (7th in EPA per pass, 1st in yards per game). They’ll battle a top-tier defense on the other side, but the Cowboys’ consistent, exceptional play along their front (fourth overall in sacks allowed, 12th in yards per carry) can create a formidable challenge for the Vikings’ pass-rush (4th in sack percentage). 

On the other side, Dallas’ defense showed notable improvement in Weeks 12 and 13 but took a step back at Detroit, although even great defenses have had similar moments at Ford Field. Overall we still see an improving group, but McCarthy has another opportunity to look his best against a Dallas-defense that’s mostly been abysmal all season (30th in EPA per pass). We wanted to find ways to justify a bet on the Cowboys, but the Vikings are never dead with O’Connell steering the ship. And frankly, our power ratings don’t score these teams as grossly disparate.

Vikings vs Cowboys SNF prediction: Vikings +5.5 (-110) available at time of publishing. Playable to 4.5.

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Game Totals Pick
Under 47.5(-110)

This total is slightly above average, but not as high as many would have projected earlier in the season. Psychologically it’s very interesting. For some reason the market inherently trusts Kevin O’Connell, even if the larger sample size suggests we shouldn’t. We realize they had one game with Max Brosmer as their starter. Still, Minnesota ranks 30th overall in EPA per pass, a metric that McCarthy affected far more than his colleagues. Well, except Brosmer. They also score just 19.6 points per game. Their ground attack has been formidable at times but they don’t run the ball enough (27th in rush play percentage, 40.05%). The Cowboys will remain far below average defensively but they’re not being served some juggernaut, either.

Minnesota’s defense may be the most consistent of any unit. We’ve had our critiques of Brian Flores, who has moments that have us scratching our heads. Top coordinators and quarterbacks can navigate the puzzles he creates, but the truth is most fall victim. Flores is extremely creative in his schemes and blitzes more than any coach in the league (48%). While Dallas has been proficient at protecting Dak Prescott, there is nothing easy about this matchup. No matter which way you pitch it, 47.5 points is still a ton. For both teams, playoff hopes are on the line. We completely understand why markets think this could turn into a showcase of scoring, but from where we’re sitting a defensive battle is just as likely. We project this to end around 44, so we have no other choice.

Vikings vs Cowboys SNF pick: Under 47.5 (-110) available at time of publishing. Playable to 46.5.

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Why Trust our NFL Picks

Through week 14 of the 2025 season our team of NFL handicappers have made against the spread and totals picks for every game. with 113 wins (and 2 pushes) our record speaks for itself. Our expert NFL picks against the spread have scored +27.4 units of profit so far this season.

WinsPushLossesProfit (betting units)
113291+27.4

At Pickswise, every NFL pick is backed by years of betting experience, advanced data analysis, and a proven track record of success. Our team of handicappers studies line movement, injury reports, historical trends, and matchup stats to deliver informed recommendations — not guesses. We publish our results openly, update our predictions as new information emerges, and never hide behind vague analysis. Whether you’re looking for expert spreads, totals, props, or parlays, our mission is simple: give you honest, well-researched picks that stand up over time.

Free NFL Picks Explained

We firmly believe expert NFL picks should be free, so you’ll find our NFL picks today, and every day of the season, right here. We publish our free NFL picks for every game, at least a few days in advance of gameday, so you know who the experts are backing without missing out on the early value in the betting markets.

There’s almost an infinite way to bet on the NFL, from NFL picks against the spread, moneyline, over/under, NFL Parlays, and NFL Prop Bets, there is a bet type for every kind of football fan, so we provide NFL picks for every bet type. Some bettors like to specialize in a single particular type of NFL pick, while others like to have a diverse range and bet on anything they feel is a value pick.

Here at Pickswise, we have something for everyone. Our team of handicappers have a wealth of experience in making NFL picks across all these betting markets, leaving no stone unturned ahead of every game and every pick of the 2025 NFL season. If you’re looking for more information on NFL bet types, You can find our expert breakdown of each below.

NFL Picks Against the Spread

The most popular way to bet on the NFL is against the spread (ATS). With these wagers, you are not picking a simple winner or loser of a game. Instead, ATS betting is placing your money that Team A wins by a certain amount of points or that Team B will keep the game closer than oddsmakers expect, in other words, not lose by that same amount of points.

For Example

Philadelphia Eagles -7 – Philadelphia must win by 8 or more points to cover the spread.
Chicago Bears +7 – Chicago must win, or lose by 6 or fewer points to cover the spread.
Tie Scenario – If the game ended 27-20 to Philadelphia, the spread would be a tie, or a push and stakes would be returned.

  • The team that covers the spread wins the game outright around 80% of the time.
  • Road teams going into games as the favorite have covered the spread at 64% so far this season
  • Teams coming off a blowout loss (20+ points) tend to rebound against the spread, 57% of the time.

Free NFL Over / Under Picks

Another exciting way to still get in on the NFL action is with totals wagers. In these bets you don’t take a side, but whether the two teams will combine to score over or under the total number of points that the oddsmakers have set. Already since sports betting has been legalized we’ve seen many occasions where a hail mary, missed FG or XP has cost over or unders bettors, so be prepared to be in for the long haul with your totals bets. We preview every game of the NFL season, providing insight into the game as a whole alongside expert NFL picks so you can make informed NFL totals bets.

  • Overall, unders have proven the value pick in recent seasons, as defenses have caught up with scoring trending down since 2021
  • Unders bets have the edge in divisional games, landing 57% of the time. This trend gets stronger late in the season (week 13 onwards), especially in cold weather conditions.
  • Unders bets have landed on 58% of primetime games, as public betting tends to have a bias for the overs in these games.

Money Line NFL Picks

Ask any seasoned NFL bettor and they’ll tell you that ATS betting is exciting, but can also be frustrating. It is important to keep in mind that NFL teams only need to win by one, of course, they’d love to win by more, but they’ll change their schemes late on to secure a win, not to ensure they cover the spread. Your research could have given you the right side, but if they win by 6 instead of 7 your -6.5 bet is a loss. Therefore a lot of bettors like to keep it simple and take our expert NFL Money Line picks and bet on the NFL straight up.

  • Through the first 4 weeks of the 2025 season 6+ point favourites have been strong straight up, with a 16-2-1 record
  • Short underdogs (+1 to +3 on the spread) win outright 43% of the time, offering better value on the moneyline than the spread
  • Underdogs in lower scoring road games (less than 42 total points) win outright 39% of the time, but often at better prices than this record suggests.

2025-26 NFL Schedule 

This will be the 106th season in league history and is set to kick off with the NFL Kick-Off game on Thursday, September 4, hosted by the defending Super Bowl Champions Philadelphia Eagles, who take on the Dallas Cowboys. The regular season will come to a conclusion on January 4, 2026 with the NFL Playoffs scheduled to begin the following weekend on the 10th, 11th & 12th of January 2026. Super Bowl LX is scheduled for February 8, 2026, at Levi’s Stadium in San Francisco, California, the home of the 49ers.

NFL Playoff Picks

You can find our NFL picks for the 2026 Playoffs, right here, for free. Wildcard Weekend is scheduled to start January 10, upon the conclusion of week 18 our experts start to make their picks and predictions for the first round of the playoffs and after each round is concluded we prepare for the coming weekend, all the way up to the Super Bowl.

NFL Playoff Picks
NFL Wildcard Weekend Picks
NFL Divisional Round Picks
NFL Conference Championship Picks

NFL Expert Picks

Our NFL Football picks will be for every game throughout the regular season, with primetime games and the top matchups each week getting additional expert coverage which will extend to every playoff game. These NFL Football picks will come alongside analysis and the latest stats and trends to consider when betting. You can also find our NFL Best Bets for the top plays of the week and a confidence rating for our expert handicapper.

Looking for alternative football picks? then head to our College Football Picks page, where you’ll find the same level of expertise from the Pickswise handicapping team for all the headline games in the 2025 NCAA football season.

More Than Just NFL Football Picks

We also specialize in every major North American sport including the MLB, NBA, NHL, College Football, and College Basketball. Check out our site every day for some of the best bets in every major athletic contest and make sure to follow us on social media as well.

Andrew Wilsher, Managing Editor of Pickswise

Statistical Approach to NFL Picks

It’s our goal to provide you with the best NFL picks in the market. Our expert handicappers are all specially selected and assessed prior to joining the team to ensure their analysis. experience and results are among the best in the industry. Each capper will put hours of research into each pick and many have built statistical models to find their moneyline, spread and over/under picks so you don’t have to. Check out all of our cappers’ free NFL picks here every week of the season. 

Andrew Wilsher, Pickswise Managing Editor

NFL Picks FAQs

To bet against the spread in the NFL you are either betting the favorite to win by x number of points or the underdog to win, or lose by fewer than x points. For example the Chiefs -7 points or the Panthers +7 points.

The number of points is set by sportsbooks and is often referred to as the line

 

Pickswise is the best website to get free NFL picks against the spread. Our handicappers provide free insight, analysis, and data to back up which way they’re siding against the spread for every NFL game. So far this NFL season our experts have secured 86 winning NFL picks for a profit of 26 units

Pickswise is the best place to get free expert NFL picks. We have the best cappers and NFL picks on the market and you can get all of our NFL picks for free! every week.

Each pick is meticulously researched by an experienced NFL handicapper, using our own data, custom-built models, and analytical methods. Our profit this season is 26 units and rising, so don’t miss out on the best NFL picks this week.