Cleveland Browns vs Baltimore Ravens Prediction, Odds and Picks for Sunday, 09/14/25

We’ve got an AFC North showdown on our hands in Week 2 as the Baltimore Ravens are set to take on the Cleveland Browns at M&T Bank Stadium on Sunday. Baltimore sure looked like the best team in football over the first 90% of its game against the Bills in Week 1, as the Ravens were dominating that game in Buffalo against a team that should be one of the best in the league this season. However, it all fell apart for the Ravens in the final 5 minutes, as the Bills scored 16 points in the waning moments of the game to steal a win in what could be the Game of the Year already. Now, Lamar Jackson and company return home for a matchup against a Browns team that should be overmatched in this one.

Cleveland played about as good of a game as you could possibly play against the Bengals in Week 1, as the Browns outgained Cincinnati significantly but ultimately missed a field goal and an extra point en route to a demoralizing 1-point loss at home. Having to take on the most dynamic offense in the NFL after suffering a heartbreaking loss is not a favorable situation for any team, much less one that is operating at a serious talent deficit like the Browns are in this game. Baltimore’s defense should bounce back nicely against Joe Flacco and a turnover-prone Cleveland offense, while Jackson, Derrick Henry and company should roll against a beleaguered Browns defense. I’ll lay the chalk with Baltimore.

Browns vs Ravens prediction: Ravens -11.5 (-110) available at time of publishing. Playable to 12.5.

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While my preferred wager in this game is on Baltimore to cover the number, I lean toward backing the Over in this contest. For starters, Baltimore should see plenty of success against the Browns’ defense, especially since the Ravens tallied a combined 60 points against Cleveland in 2 games a season ago and their offense has only gotten more dynamic and explosive since then. Given Baltimore’s recent history with blowing big leads, I’d also expect that we see an “all gas no breaks” effort from the Ravens in this one, as John Harbaugh’s team looks to put last week’s game behind them. On the other side, Cleveland doesn’t have much of a dynamic offense, but the Ravens’ defense did allow the 2nd-most EPA per dropback in Week 1, so there is a path for Flacco and the passing game to have at least some success against a familiar foe.

Browns vs Ravens pick: Over 45 (-110) available at time of publishing. Playable at that number.

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