Houston Texans vs Seattle Seahawks Prediction, Odds and MNF Picks for Monday, 10/20/25

The Houston Texans entered their bye week with much needed positivity. Of course, battling the Titans at home, a team that might be the worst in the NFL, and then dominating the Ravens with half a roster were certainly two advantageous positions. At the same time, CJ Stroud and company took advantage and did what they should have done, posting wins by margin. Particularly against Baltimore, we saw a side of the Texans’ offense that was virtually nonexistent up until that point. Stroud threw four touchdowns and their offense gained 417 total yards and 27 first downs in Charm City, completely decimating what was left of the Ravens’ defense. Houston’s defense, which has never been the problem and ranks first in opponent points per game (12.2), will surely benefit from two weeks of rest as they are healthier than they’ve been in a long time. A travel spot up to the Pacific Northwest is never easy, but two weeks for Houston to work on new schemes under first year offensive coordinator, Nick Caley, should pay dividends against a very good Seattle defense. 

Speaking of Seattle, what they did in Jacksonville last week was very impressive. After battling Tampa in Week 5 and losing a very close game at home, Seattle responded by holding the upstart Jaguars to just 273 total yards and 17 first downs at home. They also kept Trevor Lawrence and his colleagues to just four yards per play.  Perhaps most impressive, Lawrence was sacked seven times in that contest. Prior to Week 6, he was one of the best-protected quarterbacks in the league. 

We can’t say anything negative about Sam Darnold, either. The Seahawks new quarterback is top three in most passing categories and leads a potent air attack that ranks first in yards per pass (9.5). Seattle’s run game still leaves much to be desired (28th in yards per carry). 

This makes for a very interesting battle, but since we’ve barely seen positive performances from the Texans, we must give the nod to the home team, even with the hook over a 3-point spread.

Texans vs Seahawks prediction: Seahawks -3 (-115) available at time of publishing. Playable to 3.5.

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