HomeNFLNFL PredictionsIndianapolis Colts vs Los Angeles Rams Prediction, Odds and Picks

Indianapolis Colts vs Los Angeles Rams Prediction, Odds and Picks for Sunday, 09/28/25

Updated: 5:00 AM ET Sep 29, 2025

SoFi StadiumFOX

3-0

Colts

4:05 PM ETSun Sep 28

2-1

Rams

Kevin Rogers

Updated: 5:00 AM ET September 29, 2025

Show Bio

Kevin covers the NFL for Pickswise from sunny south Florida. He has been handicapping the NFL professionally since 2007, as well the NBA, MLB, NHL, college football, and college basketball. He looks forward to a profitable season at Pickswise.

@RogersPicks

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