Jacksonville Jaguars vs Tennessee Titans Prediction, Odds and Picks for Today, 11/30/25

The AFC South is quietly shaping up to be one of the most competitive divisions in football as we near the final month of the NFL regular season, and Sunday’s game between the Jacksonville Jaguars and Tennessee Titans could have massive implications in this division and playoff race within the AFC. After a horrible stretch of play for the majority of the season, the Tennessee Titans have finally found some life against the spread in recent weeks. In fact, Tennessee has now covered the spread as an underdog in 3 consecutive games, including sneaking through the back door against the Seahawks a week ago. The Titans no longer look like the worst team in the conference and this week’s matchup should be noticeably easier for Cam Ward after having to face the elite Seattle defense a week ago.

On the other side, while the Jaguars are winning games, it certainly hasn’t been pretty. In fact, you could certainly make the case that Jacksonville is the team most due for some regression across the NFL to this point. Trevor Lawrence continues to struggle mightily and with a couple of key offensive pieces not 100% healthy heading into this week, it’s hard to have confidence in Jacksonville to win by at least a touchdown on the road. Tennessee just put up a pretty feisty performance against the Texans at home a few weeks ago, so let’s go back to that well on Sunday.

Jaguars vs Titans prediction: Titans +6.5 available at time of publishing. Playable to +6

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