Minnesota Vikings vs Cleveland Browns Prediction, Odds and Picks for Today, 10/05/25

This is not a game that will excite many NFL fans this weekend, and for good reason. After all, this game is being played in the very early window in London, and features a couple struggling offenses going up against a pair of defenses that should dominate the game from the opening kick. With that in mind, I’m going to target the favorite, especially when considering the situational spot in this game. The Vikings will have the benefit of staying overseas after just competing in Europe, while the Browns are coming off a non-competitive loss against the Lions and will have to head back to the states for a game against the Steelers in just over a week’s time. All of this sets up for a pretty sluggish Cleveland team that should be expected to struggle against the Vikings defense likely to feast against a depleted Browns offensive line and wide receiver corps.

As for Minnesota, the Vikings defense has been a top 10 unit in football without a doubt, and Brian Flores should have new Browns rookie starter Dillon Gabriel in a world of hurt in his first ever NFL start. On the other side of the ball, Carson Wentz has been perfectly serviceable as a starter in Kevin O’Connell’s offense, and even though I have serious concerns about his propensity to turn the ball over, the Vikings should ride the ground game and look to grind out scoring drives against Cleveland’s stout defense. All it should take is a few scoring drives for Minnesota to win and cover this number in a spot where they’ll hold a massive travel and body clock edge on Sunday.

Vikings vs Browns prediction: Minnesota Vikings -3.5 (-110) available at time of publishing. Playable at that number. 

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This is a preposterously-low total for an NFL game, but I can only look toward the under in what should be a gross game from start to finish. As previously mentioned, Brian Flores’ defense is one that should immediately fluster Dillon Gabriel in his first NFL start, especially considering the unfamiliar environment and travel at hand for the Browns. The Browns will likely look to keep the ball on the ground considering the circumstances, which should shorten the game considerably. As for the Vikings, I have real concerns about this makeshift offensive line and their ability to block a fierce Browns pass rush that has been one of the best in football to this point. It’s hard to recommend any total under 37, but I’d rather have the under in London.

Vikings vs Browns pick: Under 36.5 (-110) available at time of publishing. Playable to 36.

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