HomeNFLNFL PredictionsPittsburgh Steelers vs New England Patriots Prediction, Odds and Picks

Pittsburgh Steelers vs New England Patriots Prediction, Odds and Picks for Sunday, 09/21/25

Updated: 5:00 AM ET Sep 22, 2025

Gillette StadiumCBS

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Steelers

1:00 PM ETSun Sep 21

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Patriots

Kevin Rogers

Updated: 5:00 AM ET September 22, 2025

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Kevin covers the NFL for Pickswise from sunny south Florida. He has been handicapping the NFL professionally since 2007, as well the NBA, MLB, NHL, college football, and college basketball. He looks forward to a profitable season at Pickswise.

@RogersPicks

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