HomeNFLNFL PredictionsSeattle Seahawks vs Carolina Panthers Prediction, Odds and Picks

Seattle Seahawks vs Carolina Panthers Prediction, Odds and Picks for Sunday, 12/28/25

Updated: 11:20 AM ET Dec 25, 2025

Bank of America StadiumFOX

12-3

Seahawks

1:00 PM ETSun Dec 28

8-7

Panthers

Seahawks vs Panthers Guest Expert Predictions

Point Spread Pick

SEA Seahawks -7.0(-110)

Reasoning

The top three teams in the NFC West are all headed to the playoffs, it’s just about who will finish as the division champion. Seattle (12-3) owns the best record in the NFC with two weeks to go, looking to creep closer towards the top seed and a first round bye. The Seahawks rallied past the Rams in overtime last Thursday, 38-37, overcoming a 16-point fourth quarter deficit. Now Seattle travels east to Carolina seeking its seventh road win in 8 tries.

The Panthers (8-7) jumped the Buccaneers for first place in the NFC South after knocking off Tampa Bay last Sunday, 23-20 as three-point home underdogs. Carolina improved to 6-1 this season off a loss and 5-1 ATS as home dogs, although 3 of the teams are not headed to the playoffs. The Panthers allowed 20 points in three of the last 4 games, while yielding a couple of touchdowns 3 times. Carolina has taken care of its business against teams with losing records, going 5-3, but is 2-4 when facing clubs owning winning records. Since throwing for 448 yards in an overtime win at Atlanta in Week 11, Panthers QB Bryce Young has not topped the 206-yard mark in any of the past 4 games. The Seahawks have allowed more than 203 passing yards once twice in 7 road games.

Seattle has posted a solid 4-1 ATS mark as a road favorite with its lone non-cover coming as 13-point chalk at Tennessee in a 30-24 victory. The Seahawks are visiting Charlotte for the first time since 2019, beating the Panthers, 30-24. Seattle last faced Carolina in 2023, outlasting the Panthers, 37-27 as Andy Dalton and Geno Smith were the starting quarterbacks. In Carolina’s last five games off a win, the Panthers scored 13, 9, 17, 9, and 17 points, while going 1-4 in those contests.

Seahawks vs Panthers prediction: Seahawks -7 available at time of publishing. Playable at that number.

You can bet on our Seahawks vs Panthers pick with BetMGM, where right now new users can activate your new BetMGM account ⚡ and receive $150 in bonus bets INSTANTLY if your first $10+ wager is a winner!

BET -7.0 NOW WITH

Kevin Rogers

Game Totals Pick

Under 42.5(-110)

Reasoning

The Seahawks have alternated the Over and Under in 7 consecutive games, coming off an easy Over in last week’s 38-37 triumph over the Rams on a 42 total. Seattle allowed 25 points in the previous 3 games before Los Angeles scored 23 points in the first three quarters. The Seahawks have not drilled back-to-back Overs since Weeks 9 and 10, when they combined to score 82 points. The offense scored a total of 1 touchdown in home wins over the Colts and Vikings before posting 4 touchdowns against the Rams a week ago.

The Panthers are on a 5-2 Under run the last 7 games, while giving up 20 points apiece against the Saints and Buccaneers the past two weeks. Prior to last Sunday’s 23-20 win over Tampa Bay, Carolina had yielded at least 27 points in 3 of its 4 previous home contests. The offense has been inconsistent for Carolina off a win, averaging 11.0 ppg in the past 5 opportunities. Also, the Panthers have scored more than 20 points in consecutive games twice. Carolina is allowing 28.1 ppg to teams owning a winning record.

Seattle’s defense ranks second in the NFL in points allowed per game at 18.6, a 3-point improvement from last season. Carolina hopes to turn around its poor rushing defense, which sits last in the league giving up 179.8 yards per game. The good news is the Seahawks own the fifth-worst running game at 95.7 yards per contest, so we’ll see if Seattle will turn to its passing game. Seeing Seattle’s trend of inconsistency towards totals and off that high-scoring game against Los Angeles along with Carolina’s offensive struggles off a win, let’s anticipate a lower-scoring contest at Bank of America Stadium.

Under 42.5 available at time of publishing. Playable to 42.

BET u42.5 NOW WITH

Kevin Rogers

Caleb Wilfinger

Published: 11:20 AM ET December 25, 2025

Show Bio

Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email contact@pickswise.com.

NFL Analysis

See All NFL News

Denver Broncos wide receiver Courtland Sutton (14) celebrates a touchdown reception with wide receiver Lil'Jordan Humphrey (17) in the fourth quarter against the Kansas City Chiefs at Empower Field at Mile High.

Denver Broncos vs Kansas City Chiefs Same Game Parlay: NFL Christmas Parlay Picks for Thursday Night Football, Week 17, feat. Courtland Sutton & Troy Franklin

The primetime game on Christmas features the Denver Broncos and Kansas City Chiefs in an AFC West showdown that has surprisingly lost some luster. Kansas City has already been eliminated from playoff...

NFLPosted 6 hours ago