Tampa Bay Buccaneers vs New Orleans Saints Prediction, Odds and Picks for Sunday, 10/26/25

It will be showdown in the NFC South when the Tampa Bay Buccaneers visit the New Orleans Saints on Sunday afternoon. Despite dealing with all kinds of adversity in the injury department, Tampa Bay looks well on its way to another division title. Baker Mayfield is playing at an MVP level, which is why his team has been able to overcome absences from receivers Mike Evans and Chris Godwin in addition to running back Bucky Irving. It is true that the Bucs have won a lot of close games, but many of those have come against decent opponents (other than the New York Jets, of course). With an opponent that is far from decent on the menu for Sunday, Tampa Bay should be able to win by more than 4 points. As such, my Buccaneers vs Saints prediction is on the visitors to win and cover.

Quite simply, the Saints stink. They managed to beat the New York Giants in Week 5, but that was only because New York committed a ridiculous 5 turnovers and forced none. Despite winning the turnover battle by 5, New Orleans still struggled to pull away. Head coach Kellen Moore’s crew followed that up with losses to New England and Chicago — the latter its third of the season by at least 12 points. The Saints have lost 5 of the last 6 head-to-head matchups, including 2 last year by a combined 32 points.

Tampa Bay Buccaneers vs New Orleans Saints prediction: Buccaneers -4 (-110) available at time of publishing. Playable at that number.

Now you can bet any of our Buccaneers vs Saints predictions at FanDuel Sportsbook, which has a great new-customer offer to take advantage of. If you sign up for FanDuel right now, you earn a welcome bonus worth up to $300 if your first $5 bet wins! Use this link 🔗 to join FanDuel right now and learn more.

The Saints do not inspire any confidence on the offensive side of the ball. They have been held under the 20-point mark 5 times this season and have scored more than 21 points just once — when they benefited from 5 Giants turnovers and were basically always playing with a short field. Spencer Rattler is nothing more than a game manager at quarterback, counted on primarily to not make mistakes — which he was accomplishing for the most part until suddenly throwing 3 interceptions in last weekend’s loss to Chicago. RB Alvin Kamara, WR Chris Olave and TE Juwan Johnson are all listed as questionable for Sunday. It’s hard to see New Orleans scoring many points, so my Buccaneers vs Saints pick is Under 47.

As well as Mayfield is playing, it’s hard to see Tampa Bay putting up a huge number. After all, it was just limited to 9 points by the Detroit Lions on Monday Night Football. Now one of the most banged-up teams in football has to play on a short week — not good news for the offense. Evans is on injured reserve after breaking his collarbone against Detroit, while Godwin and Irving are also out. The Bucs also have 2 offensive linemen who would be in the lineup on injured reserve and 2 more who are questionable for Sunday. All things considered, let’s back the under with a ton of confidence.

Tampa Bay Buccaneers vs New Orleans Saints prediction: Under 47 (-110) available at time of publishing. Playable to 45.

You can bet on our Buccaneers vs Saints pick at DraftKings Sportsbook, which has thousands of betting options available and a great new customer offer where you can get $200 in bonus bets instantly AND $200 off NFL Sunday Ticket! Click here 👈🏼 to sign up for a DraftKings account now.