Tennessee Titans vs Jacksonville Jaguars Prediction, Odds and Picks for Today, 01/04/26

We have an interesting AFC South matchup in store for us on Sunday to close out the NFL season, as the Tennessee Titans will travel to Jacksonville to take on the Jaguars in a game that means a lot more for the hosts than it does for the visitors. Jacksonville has been on an absolute tear over the second half of the season, as the Jaguars have rattled off 7 consecutive victories and have surged into contention in the AFC as a result. Liam Coen’s group is playing as well as any team across the NFL at the moment, and they’ll need to pick up a victory on Sunday in order to secure the division title and a home playoff game in Wild Card Weekend. With that in mind, it’s pretty clear that the Jaguars are going to be motivated in this game, which is obviously important to consider in the handicap.

Jacksonville’s offense has been a well-oiled machine in recent weeks, and Trevor Lawrence is currently in the midst of the best stretch of football of his career. The Clemson product has been absolutely dealing in recent weeks and he’ll be facing a Titans defense that is extremely banged up, as Tennessee is missing multiple players at cornerback and safety in the secondary. Jacksonville has also been running the ball better, which spells trouble for a Tennessee defensive front that is going through injury trouble and has already been a poor run defense this season. On the other side, the Titans offense has been playing better in recent weeks, but it’s hard to see them keeping up with one of the better offenses in football on the road. Let’s lay the points with Jacksonville.

Titans vs Jaguars prediction: Jaguars -12.5 available at time of publishing. Playable to Jaguars -13.5

If you’re looking for a new sportsbook, check out Bet365, the world’s #1 sportsbook. They have an amazing sign-up offer where you can INSTANTLY receive $150 in bonus bets from a $5 wager, regardless of whether that bet wins or loses! There’s no catch, it’s really that simple. ⏰ in time to fade or follow our experts’ Titans vs Jaguars predictions.