NFL Picks

Get expert NFL picks for every game of the 2025-26 season. Our free NFL picks are informed by key betting trends, statistical analysis and years of NFL betting experience. Bet smarter with our NFL picks this week, and every week of the NFL season.

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7:00 PM ET
Today
ABC, ESPN
Tampa Bay Buccaneers
Houston Texans
Buccaneers
Texans
Point Spread Pick
HOU Texans -3.0(+100)

Both Tampa Bay and Houston impressed in Week 1, albeit for different reasons. The Texans didn’t get a win but that doesn’t mean it was all bad news. Their defense looked in heavyweight form, limiting the Rams to just 74 rushing yards and they were in Matthew Stafford’s face for 4 quarters. Stafford and an elite group of receivers eventually figured it out enough to put up 2 touchdowns, but the Rams couldn’t eke out a score in the 1st or 4th quarters. Houston’s offense is a different story.

Surprisingly, they ran for 114 yards, but CJ Stroud faced much of the same pressure that stunted his 2024 progress. Sacked 3 times and just 2-9 in 3rd downs, Stroud struggled to accelerate his offense’s production when the team needed it most. To be fair, they were up against an underrated Rams defense, one that plainly exhibited its scary potential in Week 1. But Stroud wasn’t happy, telling the media that it was a “wake-up call.” The Texans’ chances of making any noise this season feel decreased already, with no evidence suggesting things will change along their offensive line. 

However, Monday night’s contest may offer a better opportunity. Tampa’s offense is capable of explosive plays, but they didn’t quite look like themselves in Week 1. Perhaps the loss of Liam Coen and/or the absence of Tristan Wirfs (currently recovering from a knee surgery), by far the most important piece of their offensive line, matter more than we thought. Baker still managed to overcome a feisty Atlanta defense and win on Sunday, but they were considerably outgained (258-360). Speaking of which, Michael Penix Jr. threw all over the Bucs defense last Sunday with 298 yards on 7 yards per pass. Tampa’s defensive line, a group that struggled last season, mustered just 1 sack and 3 QB hits. They were stingy against the run, but the Bucs looked below average against the pass. At home and with Stroud rallying the troops, we like the Texans to come out on fire, from the 1st quarter, and that should make all the difference.

Bucs vs Texans prediction: Texans -3 (+100) available at time of publishing. Playable at that number.

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Chris R. Farley
Game Totals Pick
Under 42.5(-110)

We have a feeling that Texans games will look very similar all season. Immediately, against a very good defense, we saw the setbacks of Houston’s offensive line, a group that couldn’t protect CJ Stroud from having to run from danger all game against the Rams. According to the New York Times, Stroud faced pressure on 41% of plays. He was also sacked 3 times and hit another 7. Without Laremy Tunsil to protect his blind side, Stroud is in the most dangerous pocket of his young career. The Texans ran the ball better than we thought they would last Sunday (114 yards), but they will face a Tampa Bay defense that held a potent Falcons’ rushing attack to just 69 yards in their opener. For years, the Bucs have been a known commodity in run defense (looking at you, Vita Vea), and this season looks no different.

Defensively, Houston was very impressive in Week 1, despite the loss. They held the Rams to just 2.9 yards per carry, 72 in total, and sacked Matthew Stafford 3 times. Of course, like Tampa, the Rams have exceptional pass catchers and Stafford was able to produce at a good enough level to score 14 points. He also converted 7-13 3rd downs. Overall, Houston’s defense protected the team’s margin throughout their first contest, a responsibility that doesn’t seem too big for them at this juncture. After opening at 46.5, this opening total fell quickly. Going to Houston will be a tough test for any offense this season, while the Texans’ offense has too many issues to trust in a higher total.

Buccaneers vs Texans pick: Under 42.5 (-110) available at time of publishing. Playable at that number.

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Chris R. Farley
Player Receiving Yards Pick
D. Schultz (HOU) - Over 35.5 rec yds(-110)

Schultz went for 3 receptions and 28 yards on 5 targets in Week 1, but the shocker was his 54% of offensive snaps. I watched the game fairly closely (being the Rams fan that I am) and was waiting for him to pop, but the Rams defense was swarming over the middle of the field. This time around, Schultz should see a snap boost with Cade Stover out now with a broken foot. Despite Schultz landing on 28 yards against a Week 1 line of 30.5, this line still sits at 35.5 with some sites flashing as high as 39.5. That alone should tell you that the market is bullish in Schultz in Week 2, and for good reason.

The Buccaneers are a much softer defensive scheme and showed major signs of withering against tight ends in 2024. Last season after their bye, tight ends averaged 6.4 targets for 4.6 receptions and 49 yards per game against Tampa Bay. Schultz led the team in targets Week 1 and I’m expecting him to be near the top again, with 6 or 7 targets likely being the case. Kyle Pitts flashed against Tampa Week 1, finishing with 8 targets, 7 receptions and 59 yards, so that indicates that Schultz has a much easier matchup in Week 2. The Texans lack a real second option in the passing game, and until that person steps up, Schultz props are ripe for the picking. 

Bobby Stanley Jr. (PropHolliday)
Same Game Parlay
Point Spread
HOU Texans -2.5
Anytime Touchdown Scorer
N. Collins (HOU) to score a TD
Player Passing Yards
B. Mayfield (TB) - 250+ pass yds

Houston Texans -2.5 over Tampa Bay Buccaneers (-115)

Houston may have lost in Week 1, but its defense was outstanding. It limited the Rams to 84 rushing yards and constantly had Matthew Stafford under pressure. We know what C.J. Stroud and the Texans’ offense are capable of producing when things are clicking, so it’s only a matter of time before this team is a well-oiled machine on both sides of the ball. That’s to say the Texans will put it entirely all together in Week 2, but offensive improvement can be expected.

Tampa Bay’s defense struggled against the pass last Sunday, watching Atlanta quarterback Michael Penix Jr. throw for 298 yards. The Buccaneers recorded just 1 sack and 3 QB hits. On the other side of the ball, the visitors are still without offensive tackle Tristan Wirfs and receiver Chris Godwin. Wirfs is arguably the best at his position in the entire NFL and Godwin – even though Emeka Egbuka looks like an extremely promising rookie – is a very reliable weapon for Baker Mayfield in the passing game. Let’s go with the Texans and give the 2.5 points.

Nico Collins to score a touchdown (+140)

There is good value on Collins to find the end zone well into plus money. The former Michigan standout scored 7 touchdowns in 12 regular-season games last year and then made 12 catches on 16 targets for 203 yards and 1 TD in a pair of playoff appearances. That sample size of success is obviously much larger than Collins’ relatively quiet performance last weekend. There is no reason to fret over a stout Rams defense keeping him under wraps. The Buccaneers, who ranked 29th in passing defense in 2024 and surrendered 27 touchdowns through the air, are unlikely to do the same.

Baker Mayfield to record 250+ passing yards (+124)

This actually doesn’t conflict much with backing the Texans to win and cover, because Mayfield will have to air it out if his team is playing from behind. Let’s hope Houston jumps out to a quick lead and forces Mayfield to hit the airwaves. If that happens, the Oklahoma product should be able to victimize the opposing secondary. Houston held the Rams to 14 points last weekend, but it gave up 224 passing yards on 8.4 yards per attempt. Mayfield did not do much in the way of yardage during Tampa Bay’s Week 1 win over Atlanta, but he at least tossed 3 touchdowns without getting picked off. He is playing with confidence, which should lead to another productive performance on MNF.

8:20 PM ET
Sun Nov 30
Denver Broncos
Washington Commanders
Broncos
Commanders
Point Spread Pick
WSH Commanders -2.5(-110)

I’m not a believer in the Broncos. Even if you are a believer, 2.5 points still isn’t enough in this Sunday Night Football showdown. The Commanders are in Washington for this one and teams generally get a 3-point bonus at home, so that means the oddsmakers rate the Broncos as on par or even as the superior of the 2 teams. That’s a no from me, dawg. Jayden Daniels is a much more dynamic quarterback than Bo Nix (and compared to almost everyone), plus he is armed with a better supporting cast. As of right now, this is by far my favorite bet of the season. 

Ricky Dimon
10:00 PM ET
Today
ESPN
Los Angeles Chargers
Las Vegas Raiders
Chargers
Raiders
Point Spread Pick
LA Chargers -3.0(-120)

The data doesn’t do justice to how well Justin Herbert and the Chargers played last Friday night. Battling their divisional foe and reigning AFC champion Kansas City Chiefs, the Chargers conquered their foe in methodical fashion. Herbert played one of the greatest games of his career, answering the Chiefs at every turn, leading scoring drives in every quarter. Along the way, the LA defense recorded 8 quarterback hits, 2 sacks, 3 tackles for a loss and 4 deflected passes. Jim Harbaugh’s defense was flying all over the field, unrelenting in their pursuit of the ball and permitting just 5 out of 14 conversion on Kansas City’s 3rd downs. It was a comprehensive showing from the Chargers and a startling indication of Harbaugh’s impact on the franchise. Herbert looked different, more confident and aggressive, and it made the Bolts feel like a legitimate Super Bowl contender. We were extremely impressed.

Harbaugh and Herbert now bring their roster to Las Vegas, against a Raiders team that also looked better than expected in Week 1. Of course, Pete Carroll’s new team was facing a Patriots program that had a ton of new parts, including a young quarterback only in his 2nd season. Raiders’ QB Geno Smith again proved why Carroll views him as such a valuable asset, carrying the offense on his shoulders and maintaining a lead throughout the game, even in hostile territory. Eventually the Patriots slowly caught up and the game was close at the end, but Vegas held on in an otherwise uneventful opener. In truth, besides a crisp performance by Geno Smith, it was a sloppy game. The Raiders got off to a nice start, but it wasn’t nearly as impressive as what we saw from the Chargers. With momentum and renewed optimism in the direction of their franchise, we love the Chargers to cover a short line.

Chargers vs Raiders prediction: Chargers -3 (-120) available at time of publishing. Playable to 3.5.

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Chris R. Farley
Game Totals Pick
Under 46.5(-110)

The Jim Harbaugh-led Chargers have only experienced success against the Raiders, putting up 34 and 22 points against their division rival last season, both wins. We think the narrative will stay the same — the Chargers are still the better team, but we saw some aspects of the Raiders’ defense that we really liked in Week 1. Firstly, they were aggressive all game, sacking Drake Maye 4 times and permitting just 60 rushing yards. They were also good when it mattered, limiting the Patriots to just 1-3 in the red zone and 4-14 on 3rd-down conversions. Eventually, Maye and his teammates moved the ball and stacked up a respectable amount of total yards (336), although most of it came after the Raiders took a comfortable lead.

Meanwhile, although Geno Smith had success in his opener, he was still sacked 4 times and the Raiders were equally pedestrian on the ground (56 rushing yards). That doesn’t bode well against a Chargers defense that played with maximum aggression last week, holding back Patrick Mahomes and Andy Reid’s historic offense in a dominant manner. A stoic Herbert and Smith give their teams the best chance of putting up points, but we see this as a defensive, divisional war between 2 programs that want to remain undefeated.

Chargers vs Raiders pick: Under 46.5 (-110) available at time of publishing. Playable to 46.

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Chris R. Farley
Same Game Parlay
Point Spread
LV Raiders +3.5
Game Totals
Under 46.5
Player Rushing Yards
J. Herbert (LAC) - Over 17.5 rush yds

Las Vegas Raiders +3.5 over LA Chargers (-110)

Both of these teams were very strong in Week 1, but I came away more impressed with what the Raiders brought to the table in their win over the Patriots. Las Vegas is a team that I was already looking to buy this season, and it’s clear through one game that the Raiders are a very well-coached unit on both sides of the ball. The upgrades on offense — specifically at the quarterback position — are as significant an improvement as any team had across the league this offseason, and Geno Smith’s impact on the offense clearly showed in Week 1.

The Chargers are coming off a great victory against the Chiefs, but given how Kansas City has looked through its first 2 games, that might not be as impressive a win as it would’ve been in years past. In a game between division rivals that should be close throughout, we’ll take Las Vegas to cover this short number as home underdogs.

Under 46.5 (-110)

While the Chargers are the team more known for their defense in this matchup, there was plenty to like about Las Vegas’ defensive performance in Week 1. In fact, the Raiders sacked Drake Maye 4 times and permitted just 60 rushing yards on the road. Las Vegas was also good when it mattered, as it limited the Patriots to just 1-of-3 in the red zone and 4-of-14 on 3rd down in the Week 1 victory.

As for the Chargers, we know that Jim Harbaugh teams tend to emphasize running the football and playing at a deliberate pace. Even with Justin Herbert’s stellar performance a week ago, there could still be some growing pains for the new pieces in this Los Angeles offense in the 2nd year of Greg Roman’s system, especially on the road. Look for both teams to take small steps back offensively on MNF.

Justin Herbert over 17.5 rushing yards (-108)

To close out our Chargers vs Raiders Same Game Parlay, let’s target Justin Herbert to clear his rushing yards prop for the 2nd consecutive week. It appears as if the former Oregon quarterback has a bit more room and leeway to operate within Roman’s system this year, and that certainly showed against the Chiefs. Herbert finished with 7 carries for 32 yards in that game, including a pivotal conversion on 3rd and long, using his legs to close out the contest. Look for him to continue to ramp up the usage with his legs in another important divisional matchup. I’ll gladly play the over at the current number.

4:25 PM ET
Sun Dec 14
Tennessee Titans
San Francisco 49ers
Titans
49ers
Point Spread Pick
TEN Titans +7.5(-110)

By the time Week 14 rolls around, #1 overall Cam Ward should have found his footing in the NFL. That’s not to say Tennessee’s offense will be a well-oiled machine at this point, but it should at least resemble something respectable. As for the 49ers, they seem to be a team on the decline. This franchise might be tempted to blow it all up sooner rather than later, and this late in the 2025 campaign it could be time to tank for a high draft pick. There’s no way I’m giving the Titans more than a touchdown.

Ricky Dimon

NFL Picks This Week

There are just 18 weeks in the NFL regular season with a maximum of 16 games per week, but NFL Betting is easily the most popular in North America amongst bettors. Our expert handicappers bring decades of experience to all of our NFL picks, providing the best insight, analysis, and value – making every single one of our free NFL picks an expert NFL pick.

Free NFL Picks Explained

We firmly believe expert NFL picks should be free, so you’ll find our NFL picks today, and every day of the season, right here. We publish our free NFL picks for every game, at least a few days in advance of gameday, so you know who the experts are backing without missing out on the early value in the betting markets.

There’s almost an infinite way to bet on the NFL, from NFL picks against the spread, moneyline, over/under, NFL Parlays, and NFL Prop Bets, there is a bet type for every kind of football fan, so we provide NFL picks for every bet type. Some bettors like to specialize in a single particular type of NFL pick, while others like to have a diverse range and bet on anything they feel is a value pick.

Here at Pickswise, we have something for everyone. Our team of handicappers have a wealth of experience in making NFL picks across all these betting markets, leaving no stone unturned ahead of every game and every pick of the 2025 NFL season. If you’re looking for more information on NFL bet types, You can find our expert breakdown of each below.

NFL Picks Against the Spread

The most popular way to bet on the NFL is against the spread (ATS). With these wagers, you are not picking a simple winner or loser of a game. Instead, ATS betting is placing your money that Team A wins by a certain amount of points or that Team B will keep the game closer than oddsmakers expect, in other words, not lose by that same amount of points.

For Example

Philadelphia Eagles -7 – Philadelphia must win by 8 or more points to cover the spread.
Chicago Bears +7 – Chicago must win, or lose by 6 or fewer points to cover the spread.
Tie Scenario – If the game ended 27-20 to Philadelphia, the spread would be a tie, or a push and stakes would be returned.

  • The team that covers the spread wins the game outright around 80% of the time.
  • Road teams on Thursday Night Football covered the spread less than 40% of the time.
  • Teams coming off a blowout loss (20+ points) tend to rebound against the spread, 57% of the time.

Free NFL Over / Under Picks

Another exciting way to still get in on the NFL action is with totals wagers. In these bets you don’t take a side, but whether the two teams will combine to score over or under the total number of points that the oddsmakers have set. Already since sports betting has been legalized we’ve seen many occasions where a hail mary, missed FG or XP has cost over or unders bettors, so be prepared to be in for the long haul with your totals bets. We preview every game of the NFL season, providing insight into the game as a whole alongside expert NFL picks so you can make informed NFL totals bets.

  • Overall, unders have proven the value pick in recent seasons, as defenses have caught up with scoring trending down since 2021
  • Unders bets have the edge in divisional games, landing 57% of the time. This trend gets stronger late in the season (week 13 onwards), especially in cold weather conditions.
  • Unders bets have landed on 58% of primetime games, as public betting tends to have a bias for the overs in these games.

Money Line NFL Picks

Ask any seasoned NFL bettor and they’ll tell you that ATS betting is exciting, but can also be frustrating. It is important to keep in mind that NFL teams only need to win by one, of course, they’d love to win by more, but they’ll change their schemes late on to secure a win, not to ensure they cover the spread. Your research could have given you the right side, but if they win by 6 instead of 7 your -6.5 bet is a loss. Therefore a lot of bettors like to keep it simple and take our expert NFL Money Line picks and bet on the NFL straight up.

  • Moneyline favourites win 66% of the time over the last two seasons, but the underdogs offer better value returns winning 33% of the time
  • Short underdogs (+1 to +3 on the spread) win outright 43% of the time, offering better value on the moneyline than the spread
  • Underdogs in lower scoring road games (less than 42 total points) win outright 39% of the time, but often at better prices than this record suggests.

2025-26 NFL Schedule 

This will be the 106th season in league history and is set to kick off with the NFL Kick-Off game on Thursday, September 4, hosted by the defending Super Bowl Champions Philadelphia Eagles, who take on the Dallas Cowboys. The regular season will come to a conclusion on January 4, 2026 with the NFL Playoffs scheduled to begin the following weekend on the 10th, 11th & 12th of January 2026. Super Bowl LX is scheduled for February 8, 2026, at Levi’s Stadium in San Francisco, California, the home of the 49ers.

NFL Playoff Picks

You can find our NFL picks for the 2026 Playoffs, right here, for free. Wildcard Weekend is scheduled to start January 10, upon the conclusion of week 18 our experts start to make their picks and predictions for the first round of the playoffs and after each round is concluded we prepare for the coming weekend, all the way up to the Super Bowl.

NFL Playoff Picks
NFL Wildcard Weekend Picks
NFL Divisional Round Picks
NFL Conference Championship Picks

NFL Expert Picks

Our NFL Football picks will be for every game throughout the regular season, with primetime games and the top matchups each week getting additional expert coverage which will extend to every playoff game. These NFL Football picks will come alongside analysis and the latest stats and trends to consider when betting. You can also find our NFL Best Bets for the top plays of the week and a confidence rating for our expert handicapper.

Looking for alternative football picks? then head to our College Football Picks page, where you’ll find the same level of expertise from the Pickswise handicapping team for all the headline games in the 2025 NCAA football season.

More Than Just NFL Football Picks

We also specialize in every major North American sport including the MLB, NBA, NHL, College Football, and College Basketball. Check out our site every day for some of the best bets in every major athletic contest and make sure to follow us on social media as well.

Andrew Wilsher, Managing Editor of Pickswise

Statistical Approach to NFL Picks

It’s our goal to provide you with the best NFL picks in the market. Our expert handicappers are all specially selected and assessed prior to joining the team to ensure their analysis. experience and results are among the best in the industry. Each capper will put hours of research into each pick and many have built statistical models to find their moneyline, spread and over/under picks so you don’t have to. Check out all of our cappers’ free NFL picks here every week of the season. 

Andrew Wilsher, Pickswise Managing Editor

NFL Picks FAQs

To bet against the spread in the NFL you are either betting the favorite to win by x number of points or the underdog to win, or lose by fewer than x points. For example the Chiefs -7 points or the Panthers +7 points.

 

 

Pickswise is the best website to get free expert NFL picks against the spread. Our handicappers provide free insight, analysis, and data to back up which way they’re siding against the spread for every NFL game. 

Pickswise is the best place to get free expert NFL picks. We have the best cappers and NFL picks on the market and you can get all of our NFL picks for free! every week. Each pick is meticulously researched by an experienced NFL handicapper, using our own data, custom-built models, and analytical methods.

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