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NFL Picks

NFL picks for every game of the 2025-26 season. Our NFL expert picks are informed by key betting trends, statistical analysis and years of NFL betting experience. +27.2 units profit, from 238 winning NFL picks so far this season is the proof.

Our NFL picks this week include against the spread picks for every game in week 16, highlighted by an all-NFC West Thursday Night Football when the Rams take on the Seahawks. Sunday Night Football will see the Patriots travel to Baltimore to face the Ravens and on Monday Night Football it’s 49ers vs Colts.

The Playoffs are now just around the corner, and both qualification and seeding is still undecided for many teams. Bears vs Packers and Buccaneers vs Panthers are the divisional matchups with the most on the line, and therefore also not to be missed.

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8:15 PM ET
Today
Amazon Prime Video
Los Angeles Rams
Seattle Seahawks
Rams
Seahawks
View Preview
Money Line Pick
SEA Seahawks Win(-108)

Evidently both the Rams and Seahawks were mentally distracted in Week 15 since neither outfit put out their best performance, but one certainly played better than the other. The Rams started slow against the Lions, tied at halftime 17-17. Then they took off, scoring 17 unanswered points in the third quarter while cruising in the fourth. Even in a high-stakes, emotional battle, Matthew Stafford and his colleagues had no problem moving the ball against a fiery, motivated Lions’ roster. Los Angeles accrued 514 total yards and 30 first downs. They also scored a touchdown on four of six red-zone possessions. It was ultimately another sterling performance by a group that’s as intimidating as any in the NFL. An asterisk from the Week 15 victory was the unfortunate loss of Devante Adams, who incurred a hamstring injury. He’s unlikely to play Thursday, which is a big loss, especially near the endzone (Adams has a league-high 14 receiving touchdowns this season).

The Seahawks were clearly looking ahead to this heavyweight matchup in Week 15. Sam Darnold and the offense generally underwhelmed, producing just 18 points, 314 total yards, and 15 first downs. The Colts’ defense came to play, as did the Seahawks, who allowed just 3.7 yards per play and 215 total yards to the Phillip Rivers’ led visitors. The Seahawks defense has an edge in Week 16, since they outrank the Rams in both EPA per pass (5th) and EPA per rush (1st). 

Los Angeles and Seattle will enter Week 16’s showdown with 11 wins each, competing not only for the NFC West crown but potentially for the #1 seed in the conference. In that sense, this is akin to a playoff matchup, with much riding on the result. Normally we side with the more experienced leadership in those instances, which means typically we’d pick Super Bowl winning coach Sean McVay and Matthew Stafford. But these circumstances are a bit different.

In a “prove-it” game, Darnold and the offense collapsed in Week 11. Although they gained plenty (414 yards), Darnold threw four interceptions, stonewalling several trips in the red-zone (they were just 1-4). But statistically the Seahawks outmatched the Rams in nearly every category except turnovers, including a 26-12 lead in first downs and better efficiency on third downs, too (7-16 compared to LAR’s 2-11). Los Angeles also went scoreless in the third and fourth quarters, held in check by a stingy Seahawks’ defense. Back in Seattle and with vengeance adding extra motivation, we must side with the home team.

Rams vs Seahawks prediction: Seahawks ML (-108) available at time of publishing. Playable at that price.

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Game Totals Pick
Over 44.5(-104)

In their first battle the Seahawks left a ton of points on the board. In short, game one ended up being an odd, low-scoring affair (40 total points), so naturally the marketplace thinks it’ll be a repeat with the division and possibly #1 seed on the line. We disagree. Seattle produced a ton of offense in the initial clash (414 total yards, 26 first downs), but turnovers upended many of their drives. Sam Darnold threw four interceptions, easily his most mistake-prone performance of the season. The Seahawks are also coming off a clunky offensive showing (18 points in Week 15), but it’s not their norm. This season they’ve averaged 27.7 points per game at Lumen Field, and it’s likely they discarded preparation for the Colts with this big clash ahead.

The Rams’ defense is one of the best in the NFL according to some metrics, mainly EPA, but we’ve seen cracks in the foundation at times, especially against elite offenses. Last week they allowed 34 points to the Lions at home, for example. The Rams’ defense also doesn’t have “that guy” yet, and they’re a young group, which means they’re prone to mistakes in these big spots.

Of course, the Rams are one of the NFL’s best offenses by nearly every metric, so we’re less concerned there. Even their rushing attack has come around, ranked 8th overall in EPA per rush. They’ll need it against the NFL’s best run-resistance. The Rams will likely be without Devante Adams on Thursday, who suffered a hamstring injury against the Lions, but Matthew Stafford and his surrounding cast have enough talent to make up for his loss. We get why the market thinks a big NFC West battle will conjure more defense, but we still have to side with these two scintillating offenses. The second half should be particularly potent, once both quarterbacks settle in.

Rams vs Seahawks prediction: Over 44.5 (-104) available at time of publishing. Playable at that number.

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Chris R. Farley
Anytime Touchdown Scorer Pick
K. Williams (LAR) to score a TD(+125)

On the Los Angeles side of things, the Rams offense has been one of the best in football all season long, and we can expect another solid showing on Thursday. Even against an excellent Seattle defense, there should be avenues for the Rams to see success on the ground and through the air. That’s where Kyren Williams comes in, as the dependable Rams running back has 10 touchdowns on the season while averaging just under 5 yards per carry in the process. Williams can also catch passes out of the backfield, which could come into play against a Seattle defense that should look to heat up Matthew Stafford and make things uncomfortable for the Rams downfield passing game. Look for Williams to find the end zone for a fourth consecutive contest on Thursday.

BET +125 NOW WITH
Anytime Touchdown Scorer Pick
J. Smith-Njigba (SEA) to score a TD(+115)

You’d be hard-pressed to find a more productive receiver than Jaxon Smith-Njigba this season. The Ohio State product is playing like a first team All-Pro in 2025, and he could potentially even putting his name into the Offensive Player of the Year conversation given his performances over the past couple of months. The Seahawks top wide receiver has tallied 4 touchdowns over the last 4 weeks, and he also saw great success against the Rams a few weeks ago, a game in which he finished with 9 receptions and 105 receiving yards. We can expect his connection with Sam Darnold to be strong once again on Sunday, especially since this is a favorable matchup against a secondary that this Seattle offense should be familiar with. While this is a pretty safe pick, I can’t ignore how good Smith-Njigba has been all season long.

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Caleb Wilfinger
Player Receiving Yards Pick
T. Ferguson (LAR) - Over 16.5 rec yds(-110)

Davante Adams is listed questionable as of Wednesday, but there is little doubt he is expected to play in this game. Adam Schefter this week on the Pat McAfee Show shared his surprise at the thought of playing Adams on a short week with this hamstring injury despite the importance of the game. My expectation is that the Rams continue to lean on that 13 personnel ( 3 tight ends, 1 running back) that they have had so much success with since Week 7. Over the last 2 weeks, all 3 Rams tight ends have played more than 60% of the snaps — and last week that number jumped to 75%. It was their base package before the Adams injury, and I can’t see any reason why they wouldn’t double down on it Thursday night.

Ferguson is easily the most athletic of the bunch and viewed as more of an oversized receiver than tight end in the traditional sense. This season he has had 17 targets, 6 receptions and 144 yards — good for 24 yards per catch. The fascinating part is that his average depth of target is 19.6 with 5.5 YAC — and yet we get this line at 16.5. Observationally, Matthew Stafford missed Ferguson last week on what would have been a walk-in 30+ yard touchdown, and Ferguson couldn’t complete a TD catch in the back of the endzone later that game. My point is that it has been a point of emphasis to get the ball into Ferguson’s the hands. A lot will be made about Colby Parkinson’s returning to Seattle, especially with the recent string of games he has put together — but I view Ferguson as the “splash play” tight end of the group.

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Bobby Stanley Jr. (PropHolliday)
Same Game Parlay
Point Spread
LA Rams -1.5
Game Totals
Under 44.5
Player Rushing Yards
K. Williams (LAR) - 60+ rush yds

Rams -1.5 (+102)

The Rams just might be the best team in the NFC. Heck, they might even be the best team in the entire NFL. A recent loss to Carolina was clearly an aberration, because Los Angeles has otherwise been on an absolute roll since Week 5. Head coach Sean McVay’s squad has won 8 of its last 9 games, a hot stretch that includes victories over 4 opponents that would be in the playoffs if the regular season ended today. That doesn’t even count this past weekend’s 41-34 win over Detroit, a team that is certainly playoff material even though it is currently occupies the first spot out of the postseason in the NFC. This 8-1 run by the Rams is highlighted by a Week 11 victory over none other than the Seahawks – a 21-19 decision in L.A. The home side picked off Seattle QB Sam Darnold 4 times and also limited the ‘Hawks to 3.9 yards per carry. Since its Week 8 bye, the only team with a winning record that Seattle has defeated is Indianapolis (8-6) — which was playing with a 44-year-old under center in Philip Rivers. 

Under 44.5 (-115)

To the surprise of no one, this week’s forecast is terrible in the Pacific Northwest. A downpour is expected for Thursday, which certainly wouldn’t be a favorable development for either offense. And even in ideal conditions, the scoreboard would not be expected to light up in this matchup between the Rams and Seahawks. After all, only 40 total points were posted when these 2 division foes squared off 2 months ago in Los Angeles. Neither defense has slowed down much since that result. The Seahawks are #4 league wide in total defense, #2 in points allowed, #3 against the run, #2 in yards per rushing attempt allowed, #7 against the pass, #1 in opponents’ yards per pass attempt, #4 in sacks and #5 in turnovers forced. The Rams are #4 in scoring defense, #9 stopping the run, #8 in yards per pass attempt allowed and #6 in turnovers forced.

Kyren Williams to record 60+ rushing yards (+109)

As good as Matthew Stafford is, moving the ball through the air is not going to be easy on Thursday night – not for either team. One, buckets of rain would be detrimental. Two, Seattle’s pass defense is outstanding. The Seahawks are surrendering only 191.4 yards per contest through the air on 6.0 yards per attempt. Head coach Mike Macdonald’s club is solid against the run, too, but not entirely dominant. Williams should be able to find some running room, just as he did in the previous head-to-head showdown. The Notre Dame product ran for 91 yards and a touchdown on just 12 carries. The ‘Hawks dominated the time of possession by almost 38 minutes to the Rams’ 22; that’s why Williams got only 12 carries. He should get a lot more on Thursday. Williams has already surpassed the 1,000-yard mark in 2025 and has rushed for 72 yards or more in 6 of the past 7 contests.

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Vote on who will win!

8:20 PM ET
Sat Dec 20
FOX
Green Bay Packers
Chicago Bears
Packers
Bears
View Preview
Money Line Pick
CHI Bears Win(+100)

One of the most consequential games on the NFL Week 16 slate comes in Chicago, where the Bears are going to take on the Green Bay Packers in a massive showdown in the NFC North. These teams just met two weeks ago in Green Bay, and the Packers were able to come out on top in a game that came down to the final possession. This time around, Chicago is in a much better position as a team, and I actually make the Bears a small favorite in this game given the key injuries that Green Bay has sustained in recent weeks. Ben Johnson’s group was just in a very difficult situational spot against the Browns a week ago, and this offense didn’t miss a beat against the stout Cleveland defense, as Chicago racked up 31 points and dominated the game from start to finish at home. Caleb Williams is playing the best football of his young NFL career at the moment, while the Bears defense has shown signs of improvement of late. Given the fact that Chicago came up just a few yards short of sending the previous meeting between these teams to overtime, it’s hard not to favor Williams and company to pick up a possible division-clinching win at home.

While Chicago has impressed me in recent weeks, the Packers are a team that I’ll be looking to fade in the immediate future, albeit through no fault of their own. Green Bay is still one of the best teams in the NFC, but the Packers’ hopes of winning a Super Bowl were essentially dashed a week ago when Micah Parsons went down with a torn ACL in a loss to the Broncos. The rest of the Green Bay defense is still very solid, but it’s hard to quantify just how much of a difference-maker Parsons is in a variety of areas. Elsewhere, the Packers might also be without top wide receiver Christian Watson in this game, and that doesn’t bode well for Jordan Love’s downfield passing efficiency against an opportunistic Bears secondary that has made a living on forcing turnovers this season. I’ll back the home ‘dog while I’m still getting plus-money in what should be a terrific game on Saturday.

Packers vs Bears prediction: Bears ML (+100) available at time of publishing. Playable to -110.

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Game Totals Pick
Over 46.5(-110)

Regardless of which team comes out on top on Saturday, the over is my preferred look on the total. While the Bears defense is improved, this is still a unit that has thrived on turnovers and has largely been unable to slow down competent opponents on a down-to-down basis this season. With that in mind, the Packers should be able to generate plenty of success in this game, even if Watson ends up sitting this one out. On the other side, the Bears offense has been absolutely rolling of late and Ben Johnson’s group is averaging nearly 27 points per game over the last four weeks. Let’s take the over in a matchup that could certainly produce some fireworks.

Over 46.5 available at time of publishing. Playable to 47.

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Caleb Wilfinger

Vote on who will win!

1:00 PM ET
Sun Dec 21
CBS
Cincinnati Bengals
Miami Dolphins
Bengals
Dolphins
View Preview
Point Spread Pick
CIN Bengals -4.0(-110)

The Cincinnati Bengals head to Miami this Sunday for a matchup against the Dolphins, and both teams are already counting down the days until next season. Cincinnati had its season derailed when QB Joe Burrow exited their Week 2 game with a turf toe injury, but things haven’t been much better since he returned. After a big win over the Baltimore Ravens on Thanksgiving night, Cincinnati has dropped two in a row to the Bills and Ravens, and they weren’t even competitive last week against Baltimore, falling 24-0. Luckily for them, they’ll be going up against a 6-8 Dolphins team that will now be turning to rookie QB Quinn Ewers after head coach Mike McDaniels announced the benching of Tua Tagovailoa. Both teams are mathematically eliminated from the playoffs, but I expect the Bengals will be the team with a stronger response after last week’s embarrassing defeat.

The Phins started turning heads during their four-game win streak, but three of those wins came against the Commanders, Saints and Jets. Additionally, they showed little life in last week’s loss to the Pittsburgh Steelers and fell behind 28-3 before scoring 2 garbage-time touchdowns. Additionally, the Bengals being shut out last week actually gives them a boost based on historical trends; since 2015, teams that were shut out in the previous week are 35-17-3 against the spread in their next game and a perfect 5-0 ATS this season. This marked the Bengals’ first shutout with Burrow as the QB, and there’s no doubt in my mind that he’ll want to bounce back in a big way.Finally, McDaniel and the Dolphins have been awful on short rest; they’re just 3-10 since he took over, losing by 8.2 PPG. Although the Bengals have struggled this year, they’ll be facing a rookie QB in his first start after a disappointing loss; give me Cincinnati to win big on Sunday.

Bengals vs Dolphins prediction: Bengals -4 (-110) available at the time of publishing, playable down to -5.5.

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Game Totals Pick
Over 47.5(-110)

I expect Cincinnati to win big this weekend, and they’re going to need to do most of the scoring to push this one over. However, I do think Miami can still put up points, even with a rookie QB, because of how bad this Bengals defense has been all season. Cincinnati is allowing 31.2 PPG (last in the NFL), and although they’ve had to face Lamar Jackson twice, Josh Allen and Drake Maye over the last four weeks, they’ve allowed plenty of points to quarterbacks that are a tier below those three. They gave up 39 points to the Justin Fields-led Jets in Week 8, 48 to Carson Wentz and the Vikings in Week 3 and 65 over 2 games against a Steelers team that averages just 24 PPG. I expect Miami to rely on RB De’Von Achane even more with Ewers under center, especially because the Bengals allow 5.3 yards per carry (30th in the NFL). 

On the flip side, I’m not high on this Miami defense either. They’re giving up 6.8 yards per pass attempt (20th in the NFL) and will now face a Bengals offense with extra motivation after being shut out. Additionally, Cinci scored 32 and 34 before last week’s shutout, and it looks like they’ll be getting WR Tee Higgins back from a concussion. Although Higgins will likely play, Miami could miss some key pieces on defense. S Minkah Fitzpatrick is doubtful, and leading tackle LB Jordyn Brooks is questionable and didn’t practice on Wednesday. This defense is beat up and is playing on short rest; I can’t see them suddenly turning things around. All in all, I expect this game to end in the 35-17 range, which should be enough to cash the Over.

Bengals vs Dolphins prediction: Over 47.5 (-110) available at the time of publishing, playable up to 48.5.

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8:20 PM ET
Sun Dec 21
NBC
New England Patriots
Baltimore Ravens
Patriots
Ravens
View Preview
Point Spread PickBest Bet
NE Patriots +3.0(-115)

For the first time all season, the Baltimore Ravens finally had an easy win in week 15. Of course, Cincinnati seemed deflated from the very start of last week’s game, and a Joe Burrow lead offense was out of its rhythm, failing to score a single point. The ravens deserve credit all around, they showed up and got the job done and they must-win situation, but it still doesn’t improve that their struggles have ceased. We also can’t dismiss that Baltimore still ranks a lowly 20th in total offensive EPA metrics, and they’re not much better on defense either (16th). Their secondary is even more concerning, ranked 19th in defensive EPA per pass and permitting 233.3 passing yards per game (26th). Even worse, only the 49ers sack the quarterback less (Baltimore ranks 31st, taking down the quarterback on only 4.14% of plays). We hate that for their matchup on Sunday night.

There is no reasonable evidence that suggests the Ravens are a better team than the Patriots entering Week 16. Baltimore’s edge is that they’re at home and that they have more experience in big-time matchups like this, a cyclical playoff participant under the era of John Harbaugh and Lamar Jackson. But when it comes to this season, the Patriots are the better team in every category. Offensively they rank 6th in total offensive EPA and 12th in total defensive EPA, not to mention they’re coming off a 10-game winning streak, which was broken in Week 15.

Speaking of Week 15, we’re not concerned about the Patriots because of one flawed half. Many teams fall victim to the magic of Josh Allen, who engineered yet another second half comeback last Sunday. New England showed its youth and inexperience last weekend, but otherwise they’ve been one of the most consistent programs in the NFL. In fact, only the Seahawks and Rams, two other 11-3 outfits, have a better point-differential than Mike Vrabel’s team (+7.6). 

Especially since they’re coming off a loss, there’s simply no way we could bet on the Ravens here. Too many times we’ve seen their defense capitulate, and even in an easy win last week, their offense was rather pedestrian (317 total yards, 15 first downs). Meanwhile, the Patriots have been a well-oiled machine and one of the best ATS teams all season (8-5-1, 61.5%). If we’re getting a field goal with the visitors, we’re taking it.

Patriots vs Ravens: Patriots +3 (-110) available at time of publishing. Playable at that number.

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Game Totals Pick
Over 48.0(-110)

This total is curiously high. Maybe part of that is because Baltimore will be unseasonably mild and calm on Sunday night, forecasted to be in the mid-40s — a perfect night for football. Perhaps it will become a perfect night for scoring, too. The market is certainly sending a signal by posting this above 47, a prime key number in totals.

Matchup wise, it makes sense. New England’s defense has mostly been very good this season — but it is also coming off a contest in which it got exposed by a dynamic quarterback. Arguably no NFL quarterback is as dynamic as Lamar Jackson, a true outlier athlete with a legitimate rifle of an arm to boot — very Josh Allen-like. The market is likely responding to the fact that New England’s schedule has featured very few top-tier offenses. In fact, according to EPA metrics, they Pats have only clashed with two top-15 offenses this season (BUF, PIT). Despite Baltimore’s transgressions this season, it can overwhelm any defense when functioning at a high level. 

The Patriots’ offense needs no introduction at this point, nor does the missteps of the Ravens’ defense. Defensively, Week 15 was easily Baltimore’s most impressive showing all season — blanking the Bengals and holding Joe Burrow and company to only 298 total yards. Despite holding the ball for nearly two-thirds of the game (39:19), Cincinnati went 3-for-15 on third-down conversions, too. Still, we haven’t seen that version of the Ravens’ defense for any consistent stretch all year — it’s a group that permits 344.4 yards per game (23rd). Both offenses are in a good spot and I trust both teams to rely on their production in this huge Sunday night game. I can only look at the over.

Patriots vs Ravens prediction: Over 48 (-110) available at time of publishing. Playable at that number.

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Why Trust our NFL Picks

Through week 15 of the 2025 season our team of NFL handicappers have made against the spread and totals picks for every game. with 238 wins (and 3 pushes) our record speaks for itself. Our expert NFL picks have scored +27.2 units of profit so far this season.

NFL PickWinsPushLossesProfit (betting units)
Sides (Moneyline/ATS)121299+23.4
Totals (Over / Under)1171103+3.8
Total2383202+27.2

At Pickswise, every NFL pick is backed by years of betting experience, advanced data analysis, and a proven track record of success. Our team of handicappers studies line movement, injury reports, historical trends, and matchup stats to deliver informed recommendations — not guesses. We publish our results openly, update our predictions as new information emerges, and never hide behind vague analysis. Whether you’re looking for expert spreads, totals, props, or parlays, our mission is simple: give you honest, well-researched picks that stand up over time.

Free NFL Picks Explained

We firmly believe expert NFL picks should be free, so you’ll find our NFL picks today, and every day of the season, right here. We publish our free NFL picks for every game, at least a few days in advance of gameday, so you know who the experts are backing without missing out on the early value in the betting markets.

There’s almost an infinite way to bet on the NFL, from NFL picks against the spread, moneyline, over/under, NFL Parlays, and NFL Prop Bets, there is a bet type for every kind of football fan, so we provide NFL picks for every bet type. Some bettors like to specialize in a single particular type of NFL pick, while others like to have a diverse range and bet on anything they feel is a value pick.

Here at Pickswise, we have something for everyone. Our team of handicappers have a wealth of experience in making NFL picks across all these betting markets, leaving no stone unturned ahead of every game and every pick of the 2025 NFL season. If you’re looking for more information on NFL bet types, You can find our expert breakdown of each below.

NFL Picks Against the Spread

The most popular way to bet on the NFL is against the spread (ATS). With these wagers, you are not picking a simple winner or loser of a game. Instead, ATS betting is placing your money that Team A wins by a certain amount of points or that Team B will keep the game closer than oddsmakers expect, in other words, not lose by that same amount of points.

For Example

Philadelphia Eagles -7 – Philadelphia must win by 8 or more points to cover the spread.
Chicago Bears +7 – Chicago must win, or lose by 6 or fewer points to cover the spread.
Tie Scenario – If the game ended 27-20 to Philadelphia, the spread would be a tie, or a push and stakes would be returned.

  • The team that covers the spread wins the game outright around 80% of the time.
  • Road teams going into games as the favorite have covered the spread at 64% so far this season
  • Teams coming off a blowout loss (20+ points) tend to rebound against the spread, 57% of the time.

Free NFL Over / Under Picks

Another exciting way to still get in on the NFL action is with totals wagers. In these bets you don’t take a side, but whether the two teams will combine to score over or under the total number of points that the oddsmakers have set. Already since sports betting has been legalized we’ve seen many occasions where a hail mary, missed FG or XP has cost over or unders bettors, so be prepared to be in for the long haul with your totals bets. We preview every game of the NFL season, providing insight into the game as a whole alongside expert NFL picks so you can make informed NFL totals bets.

  • Overall, unders have proven the value pick in recent seasons, as defenses have caught up with scoring trending down since 2021
  • Unders bets have the edge in divisional games, landing 57% of the time. This trend gets stronger late in the season (week 13 onwards), especially in cold weather conditions.
  • Unders bets have landed on 58% of primetime games, as public betting tends to have a bias for the overs in these games.

Money Line NFL Picks

Ask any seasoned NFL bettor and they’ll tell you that ATS betting is exciting, but can also be frustrating. It is important to keep in mind that NFL teams only need to win by one, of course, they’d love to win by more, but they’ll change their schemes late on to secure a win, not to ensure they cover the spread. Your research could have given you the right side, but if they win by 6 instead of 7 your -6.5 bet is a loss. Therefore a lot of bettors like to keep it simple and take our expert NFL Money Line picks and bet on the NFL straight up.

  • Through the first 4 weeks of the 2025 season 6+ point favourites have been strong straight up, with a 16-2-1 record
  • Short underdogs (+1 to +3 on the spread) win outright 43% of the time, offering better value on the moneyline than the spread
  • Underdogs in lower scoring road games (less than 42 total points) win outright 39% of the time, but often at better prices than this record suggests.

2025-26 NFL Schedule 

This will be the 106th season in league history and is set to kick off with the NFL Kick-Off game on Thursday, September 4, hosted by the defending Super Bowl Champions Philadelphia Eagles, who take on the Dallas Cowboys. The regular season will come to a conclusion on January 4, 2026 with the NFL Playoffs scheduled to begin the following weekend on the 10th, 11th & 12th of January 2026. Super Bowl LX is scheduled for February 8, 2026, at Levi’s Stadium in San Francisco, California, the home of the 49ers.

NFL Playoff Picks

You can find our NFL picks for the 2026 Playoffs, right here, for free. Wildcard Weekend is scheduled to start January 10, upon the conclusion of week 18 our experts start to make their picks and predictions for the first round of the playoffs and after each round is concluded we prepare for the coming weekend, all the way up to the Super Bowl.

NFL Playoff Picks
NFL Wildcard Weekend Picks
NFL Divisional Round Picks
NFL Conference Championship Picks

NFL Expert Picks

Our NFL Football picks will be for every game throughout the regular season, with primetime games and the top matchups each week getting additional expert coverage which will extend to every playoff game. These NFL Football picks will come alongside analysis and the latest stats and trends to consider when betting. You can also find our NFL Best Bets for the top plays of the week and a confidence rating for our expert handicapper.

Looking for alternative football picks? then head to our College Football Picks page, where you’ll find the same level of expertise from the Pickswise handicapping team for all the headline games in the 2025 NCAA football season.

More Than Just NFL Football Picks

We also specialize in every major North American sport including the MLB, NBA, NHL, College Football, and College Basketball. Check out our site every day for some of the best bets in every major athletic contest and make sure to follow us on social media as well.

Andrew Wilsher, Managing Editor of Pickswise

Statistical Approach to NFL Picks

It’s our goal to provide you with the best NFL picks in the market. Our expert handicappers are all specially selected and assessed prior to joining the team to ensure their analysis. experience and results are among the best in the industry. Each capper will put hours of research into each pick and many have built statistical models to find their moneyline, spread and over/under picks so you don’t have to. Check out all of our cappers’ free NFL picks here every week of the season. 

Andrew Wilsher, Pickswise Managing Editor

NFL Picks FAQs

To bet against the spread in the NFL you are either betting the favorite to win by x number of points or the underdog to win, or lose by fewer than x points. For example the Chiefs -7 points or the Panthers +7 points.

The number of points is set by sportsbooks and is often referred to as the line

 

Pickswise is the best website to get free NFL picks against the spread. Our handicappers provide free insight, analysis, and data to back up which way they’re siding against the spread for every NFL game. So far this NFL season our experts have secured 86 winning NFL picks for a profit of 26 units

Pickswise is the best place to get free expert NFL picks. We have the best cappers and NFL picks on the market and you can get all of our NFL picks for free! every week.

Each pick is meticulously researched by an experienced NFL handicapper, using our own data, custom-built models, and analytical methods. Our profit this season is 26 units and rising, so don’t miss out on the best NFL picks this week.