NFL Picks

NFL picks for every game of the 2025-26 season. Our NFL expert picks are informed by key betting trends, statistical analysis and years of NFL betting experience. +12.4 units of profit, from 144 winning picks so far this season is the proof.

Our NFL picks this week include against the spread picks for every game in week 10, highlighted by Broncos vs Raiders on Thursday night football, Chargers vs Steelers on SNF and Monday Night football, featuring Packers vs Eagles.

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Point Spread Pick

PHI Eagles +2.5(-110)

Reasoning

The betting market is still showing love to the Green Bay Packers, even after a disastrous loss to the Carolina Panthers at home this past Sunday. Green Bay notoriously plays with their food, and clearly they didn’t prepare well enough for a Panthers’ squad that’s vastly improved this season. We’ve seen this shtick from the Packers before; falling asleep in quarters 1-3 before waking up in the fourth and attempting to right their wrongs. It was too little too late in Week 9, as Carolina kicked the game-winning field goal as time expired. Although they gained 369 yards, the Packers’ offense sputtered in the red zone (1-5). Perhaps even more concerning is the inconsistency of their defense. Micah Parsons’ effect on the Packers’ defense has been obvious in many big games, but he barely made an impact in Week 9 (1 tackle for a loss, 1 solo tackle, 0 QB hits, 0 sacks). As a unit they held the Panthers to just 265 yards, but the visitors were also 2-3 in the red zone and were able to play mistake-free football.

If the Packers let down again this week, that’s going to be a huge issue. The Eagles are coming off a bye-week and their general manager, inarguably the best in the league, has once again reloaded their hyper-talented roster before the deadline, especially on defense. Philly picked up Cornerback Jaire Alexander, corner Michael Carter II, and edge rusher Jaelan Phillips, adding depth to groups that haven’t been as effective this season. Eagles head coach Nick Sirianni is also very good after a bye week, 4-0 since taking over as the team’s leader and winning by an average margin of 10 points per game. Green Bay has played their best football against their best competition, but this is a huge step up in class against a Philly squad that takes pride in being the cream of the NFC’s crop. Philadelphia is also healthy and playing their best football before the break, pushing past Minnesota and New York before the bye.

Eagles vs Packers prediction: Philadelphia Eagles +2.5 (-110) available at time of publishing. Playable to 1.5.

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Game Totals Pick

Over 45.0(-110)

Reasoning

The Packers loss in Week 9 was bad enough, losing Tucker Kraft made it sting even more. The dependable tight end has become one of the best in the NFL, tying all receivers with 6 touchdowns this season. He was seen taking over the game with Jordan Love just 2 weeks when they ran roughshod on the Steelers, and he adds a matchup nightmare for opposing defenses – who must contend with a slew of high-end talent in Green Bay’s receiving corps. The Packers will be fine, but adjustments will need to be made. This week they’ll face an Eagles’ defense that hasn’t been stellar for any stretch this season, but moves before the trade deadline suggest they’re all-in for another Super Bowl run with Vic Fangio leading the unit. The Pack have been mostly electric at home, averaging 362 yards per game, although last week’s outing (13 points) was a bit of a head-scratcher.

In what many saw as an outlier since it was a “sandwich spot,” pinned in between two high-profile matchups, we’re going to give a pass to the home team for Week 10. We think they bring the heat and get into the 20s, regardless of the game’s result.

On the other side, a 2-week break is a good thing for an Eagles’ offense that’s been sputtering plenty this season, too. The good news is they looked in top-form before their bye, putting up 788 yards and 66 points in their last 2 outings. The off-and-on nature of the Green Bay defense is tough to figure out, although after a poor showing in Week 9 we project a far better performance on Monday night. Still, the Eagles’ ability to score 20 or more points, which they have accomplished in 6 of 8 contests this season, should not be ignored either. This is another total in limbo between key numbers, but we expect Philly’s trend towards the over (5-3 ATS) to continue in this affair.

Eagles vs Packers pick: Over 45 (-110) available at time of publishing. Playable to 46.

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Chris R. Farley

Anytime Touchdown Scorer Pick

J. Hurts (PHI) to score a TD(+115)

Reasoning

It’s rare for me to go with a TD scorer as my best player prop bet for Monday Night Football, but when you see Jalen Hurts at plus-money odds in primetime, it deserves the trigger-pull for Eagles vs Packers. Hurts has 5 rushing touchdowns on the season and has been kept out of the end zone for 2 straight games. The Packers have allowed only 1 rushing TD on the season to an opposing QB (Dak Prescott in Week 4), but Hurts is not your average mobile QB, considering how often the Tush Push is used in Philadelphia.

Aside from the value I feel we’re getting with Hurts, there’s the off-field topic of Green Bay submitting a proposal to the NFL to make the tush push illegal. Philadelphia hasn’t been shy about their use of the play this season and shouldn’t miss an opportunity to display it once again on MNF.

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Bobby Stanley Jr. (PropHolliday)

Same Game Parlay

Money Line

PHI Eagles Win

Player Receptions

S. Barkley (PHI) - Over 2.5 recs

Player Receiving Yards

S. Barkley (PHI) - Over 14.5 rec yds

Anytime Touchdown Scorer

J. Jacobs (GB) to score a TD

Reasoning

Philadelphia Eagles ML over Green Bay Packers (+100)

The Packers are coming off a bad home loss to the Panthers – a result that looks even worse after Carolina lost 17-7 to New Orleans at home on Sunday. For Green Bay, both sides of the ball have been all over the place. Micah Parsons has been predictably dominant at times, but in other games he can disappear. Against the Panthers, he had nothing more than one tackle for loss and one solo tackle.

You have to think the Eagles are well coached to the extent that they can game-plan around Parsons, especially given that they just enjoyed a bye week. Philadelphia will be well-rested and well-prepared. Under head coach Nick Sirianni, Philly is 4-0 SU coming out of its bye week with an average margin of victory of 10 points. As slight underdogs, the visitors have great value on the money line.

Saquon Barkley over 2.5 receptions (-136)
Saquon Barkley over 14.5 receiving yards (-114)

The best way to deal with a formidable pass rush, of course, is to get the ball out of your hands quickly. Eagles QB Jalen Hurts knows how to do that, and he will be happy to dump it off to Barkley coming out of the backfield. Barkley has made at least 3 catches on 5 occasions already this season, including 4 or more 4 times. He has gained at least 24 receiving yards in 4 contests. The Packers have allowed the 10th-most receptions (41) to opposing running backs so far in 2025, so this should be a favorable matchup for Barkley in that regard.

Josh Jacobs to score a touchdown (-155)

I’m not too concerned with the Eagles’ ability to win even if Jacobs finds the end zone. After all, we can accept that as a given; Jacobs always seems to score a touchdown. The former Alabama standout has scored 10 TDs in 8 outings this season; only once – at Cleveland in Week 3 – has he failed to do so. When these 2 teams squared off in the 2024 playoffs, Jacobs racked up 121 yards from scrimmage and 1 touchdown. It’s also worth noting that Philly’s defense has allowed 10 TDs on the ground – tied for the 7th-most in the NFL through 9 weeks.

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Why Trust our NFL Picks

Through the first nine weeks of the 2025 season our record speaks for itself. Our team of handicappers have racked up 73 winning NFL against the spread and moneyline picks (and 1 push), for +8.4 units of profit. On top of that, our NFL over/under picks have landed on 67 games (and 1 push), for a profit of +4 units. When you combine the two, our expert NFL picks have scored +12.4 units of profit so far this season.

Pick	Wins	Losses	Profit (betting units)
Sides (ATS & Moneyline)	73	60	+8.4
Over/Under	71	62	+4
Total	144	122	+12.4

At Pickswise, every NFL pick is backed by years of betting experience, advanced data analysis, and a proven track record of success. Our team of handicappers studies line movement, injury reports, historical trends, and matchup stats to deliver informed recommendations — not guesses. We publish our results openly, update our predictions as new information emerges, and never hide behind vague analysis. Whether you’re looking for expert spreads, totals, props, or parlays, our mission is simple: give you honest, well-researched picks that stand up over time.

Free NFL Picks Explained

We firmly believe expert NFL picks should be free, so you’ll find our NFL picks today, and every day of the season, right here. We publish our free NFL picks for every game, at least a few days in advance of gameday, so you know who the experts are backing without missing out on the early value in the betting markets.

There’s almost an infinite way to bet on the NFL, from NFL picks against the spread, moneyline, over/under, NFL Parlays, and NFL Prop Bets, there is a bet type for every kind of football fan, so we provide NFL picks for every bet type. Some bettors like to specialize in a single particular type of NFL pick, while others like to have a diverse range and bet on anything they feel is a value pick.

Here at Pickswise, we have something for everyone. Our team of handicappers have a wealth of experience in making NFL picks across all these betting markets, leaving no stone unturned ahead of every game and every pick of the 2025 NFL season. If you’re looking for more information on NFL bet types, You can find our expert breakdown of each below.

NFL Picks Against the Spread

The most popular way to bet on the NFL is against the spread (ATS). With these wagers, you are not picking a simple winner or loser of a game. Instead, ATS betting is placing your money that Team A wins by a certain amount of points or that Team B will keep the game closer than oddsmakers expect, in other words, not lose by that same amount of points.

For Example

Philadelphia Eagles -7 – Philadelphia must win by 8 or more points to cover the spread.
Chicago Bears +7 – Chicago must win, or lose by 6 or fewer points to cover the spread.
Tie Scenario – If the game ended 27-20 to Philadelphia, the spread would be a tie, or a push and stakes would be returned.

NFL spread betting trends 2025

The team that covers the spread wins the game outright around 80% of the time.
Road teams going into games as the favorite have covered the spread at 64% so far this season
Teams coming off a blowout loss (20+ points) tend to rebound against the spread, 57% of the time.

Free NFL Over / Under Picks

Another exciting way to still get in on the NFL action is with totals wagers. In these bets you don’t take a side, but whether the two teams will combine to score over or under the total number of points that the oddsmakers have set. Already since sports betting has been legalized we’ve seen many occasions where a hail mary, missed FG or XP has cost over or unders bettors, so be prepared to be in for the long haul with your totals bets. We preview every game of the NFL season, providing insight into the game as a whole alongside expert NFL picks so you can make informed NFL totals bets.

NFL over / under betting trends

Overall, unders have proven the value pick in recent seasons, as defenses have caught up with scoring trending down since 2021
Unders bets have the edge in divisional games, landing 57% of the time. This trend gets stronger late in the season (week 13 onwards), especially in cold weather conditions.
Unders bets have landed on 58% of primetime games, as public betting tends to have a bias for the overs in these games.

Money Line NFL Picks

Ask any seasoned NFL bettor and they’ll tell you that ATS betting is exciting, but can also be frustrating. It is important to keep in mind that NFL teams only need to win by one, of course, they’d love to win by more, but they’ll change their schemes late on to secure a win, not to ensure they cover the spread. Your research could have given you the right side, but if they win by 6 instead of 7 your -6.5 bet is a loss. Therefore a lot of bettors like to keep it simple and take our expert NFL Money Line picks and bet on the NFL straight up.

NFL Moneyline betting trends

Through the first 4 weeks of the 2025 season 6+ point favourites have been strong straight up, with a 16-2-1 record
Short underdogs (+1 to +3 on the spread) win outright 43% of the time, offering better value on the moneyline than the spread
Underdogs in lower scoring road games (less than 42 total points) win outright 39% of the time, but often at better prices than this record suggests.

2025-26 NFL Schedule

This will be the 106th season in league history and is set to kick off with the NFL Kick-Off game on Thursday, September 4, hosted by the defending Super Bowl Champions Philadelphia Eagles, who take on the Dallas Cowboys. The regular season will come to a conclusion on January 4, 2026 with the NFL Playoffs scheduled to begin the following weekend on the 10th, 11th & 12th of January 2026. Super Bowl LX is scheduled for February 8, 2026, at Levi’s Stadium in San Francisco, California, the home of the 49ers.

NFL Playoff Picks

You can find our NFL picks for the 2026 Playoffs, right here, for free. Wildcard Weekend is scheduled to start January 10, upon the conclusion of week 18 our experts start to make their picks and predictions for the first round of the playoffs and after each round is concluded we prepare for the coming weekend, all the way up to the Super Bowl.

NFL Playoff Picks
NFL Wildcard Weekend Picks
NFL Divisional Round Picks
NFL Conference Championship Picks

NFL Expert Picks

Our NFL Football picks will be for every game throughout the regular season, with primetime games and the top matchups each week getting additional expert coverage which will extend to every playoff game. These NFL Football picks will come alongside analysis and the latest stats and trends to consider when betting. You can also find our NFL Best Bets for the top plays of the week and a confidence rating for our expert handicapper.

Looking for alternative football picks? then head to our College Football Picks page, where you’ll find the same level of expertise from the Pickswise handicapping team for all the headline games in the 2025 NCAA football season.

More Than Just NFL Football Picks

We also specialize in every major North American sport including the MLB, NBA, NHL, College Football, and College Basketball. Check out our site every day for some of the best bets in every major athletic contest and make sure to follow us on social media as well.

Andrew Wilsher, Managing Editor of Pickswise

Statistical Approach to NFL Picks

It’s our goal to provide you with the best NFL picks in the market. Our expert handicappers are all specially selected and assessed prior to joining the team to ensure their analysis. experience and results are among the best in the industry. Each capper will put hours of research into each pick and many have built statistical models to find their moneyline, spread and over/under picks so you don’t have to. Check out all of our cappers’ free NFL picks here every week of the season.

Andrew Wilsher, Pickswise Managing Editor

NFL Picks FAQs

How Do You Pick Against The Spread In The NFL?

To bet against the spread in the NFL you are either betting the favorite to win by x number of points or the underdog to win, or lose by fewer than x points. For example the Chiefs -7 points or the Panthers +7 points.

The number of points is set by sportsbooks and is often referred to as the line

What Is The Best Website For NFL Picks Against The Spread?

Pickswise is the best website to get free NFL picks against the spread. Our handicappers provide free insight, analysis, and data to back up which way they’re siding against the spread for every NFL game. So far this NFL season our experts have secured 86 winning NFL picks for a profit of 26 units

Where Is The Best Place To Get NFL Picks?

Pickswise is the best place to get free expert NFL picks. We have the best cappers and NFL picks on the market and you can get all of our NFL picks for free! every week.

Each pick is meticulously researched by an experienced NFL handicapper, using our own data, custom-built models, and analytical methods. Our profit this season is 26 units and rising, so don’t miss out on the best NFL picks this week.