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NFL Picks

NFL picks for every game of the 2025-26 season. Our NFL expert picks are informed by key betting trends, statistical analysis and years of NFL betting experience. +93.3 units profit, from 304 winning NFL picks across the 2025 regular season and playoffs is the proof.

NFL Picks against the spread and over/under for the Conference Championship games:

AFC Championship: Patriots vs Broncos

NFC Championship: Rams vs Seahawks

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6:30 PM ET
Sun Jan 25
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Money Line PickBest Bet
LA Rams Win(+125)

With only 3 games left in the NFL season, we will do our best not to regurgitate the same data points and factoids that have built up all year. By this point, you know who these teams are.

That doesn’t change the fact that the NFC championship game is wildly intriguing for many reasons. Los Angeles and Seattle are 2 of the biggest rivals in the NFL, neck and neck at the top of the NFC West for the last 4 months. Sunday will mark their 3rd meeting this season. The mutual familiarity certainly makes handicapping it a tougher gig. In short, there won’t be many (if any) surprises for the athletes or coaches that could provide an edge for prospective bettors. For example, the Rams have seen the nuances and vigor of the Seattle defense, as the Seahawks have seen the explosive, dynamic qualities of the high-octane Los Angeles offense. Neither will be caught off guard.

And if we add up some of the statistics from their previous 2 games this season, you’ll find they performed remarkably similar:

  • Yards — Rams: 830, Seahawks: 829
  • Points — Rams: 58, Seahawks: 57
  • Time of Possession — Rams: 62:44, Seahawks: 63:63
  • Plays — Rams: 138, Seahawks: 142

There is, however, a very clear edge at quarterback. Sam Darnold has completed 2 consecutive exceptional seasons as the thrower of 2 separate offenses. With the Vikings and Seahawks, he’s lost just 6 regular-season games the last 2 years. That’s extremely impressive. But the playoffs are a different story.

Darnold wasn’t needed much last Saturday, since the Seahawks’ special teams and defense created an immediate 17-0 lead. He threw the ball just 17 times, completing 12 of his passes for a humble 124 yards. Markets responded positively because they had no other choice, but that doesn’t mean last Saturday meant anything to determine Darnold’s playoff poise (or lack thereof). 

In his only other playoff game as a professional quarterback, he was awful. Even more compelling, the loss was against the very same Rams. A budding defense that’s matured and shown more consistency this season (10th in total defensive EPA), the Rams rattled Darnold last January, forcing him into 9 sacks, a forced fumble and an interception. We’d argue he had better offensive talent in Minnesota (although his 2024 Minnesota squad and this year’s Seahawks offense are both 15th in total EPA), too. 

Matthew Stafford and Sean McVay have been here before. As good as Seattle’s defense is, the Rams went up and down the field and gained 581 yards in Lumen Field just 1 month ago. Stafford has been unstoppable this season, which is why he’s the odds-on favorite (-450 at FanDuel) to win his first NFL MVP award. Seattle’s defense is scary good and their home-field advantage is real, but the Rams have championship experience and we know that they’re clutch in big moments. Darnold still needs to prove it.

Rams vs Seahawks best bet: Rams ML (+125) available at time of publishing. Playable to +100.

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Game Totals Pick
Under 47.5(-110)

The Rams’ best unit is their offense, and the Seahawks’ best unit is their defense. To our readers, I’m sure both statements will receive the proverbial “duh.” The greater point is this game’s total, which is curiously high at 47.5, is tough to evaluate when the Rams have the ball. 

LA’s offense has been one of the best in the NFL without deviation (2nd overall in total EPA behind the Patriots, who had a far easier schedule). From our perspective, there is no better group in the league. In their last matchup, the Rams gained 581 yards. That reality hardly supports a narrative where Seattle’s defense will limit Stafford and company on Sunday, especially considering it was only 4 weeks ago. The Rams also outpaced the Seahawks in first downs (26 to 22) and trips to the red zone, entering scoring territory on 6 different occasions. This season, the Seahawks have given up fewer points than any other defense in the league (16.6), but against the Rams those numbers inflate (21, 37). 

Of course, the Seahawks’ defense and special teams are also capable of scoring on their own or creating easy scoring opportunities for their offense. We saw that multiple times last week. The Seattle offense depends on its defense and big plays to score points; they rank as the most explosive in the NFL (1st in points per play). But LA prides itself at limiting big plays, 6th overall in the same category defensively. Either way, the essence of the “Darnold-led offense” hasn’t changed. A year ago in Minnesota, many of his statistics were average, as they are this season (13th in pass yards per game, 28th in interceptions per game), but explosive pass plays and an aggressive defense created a litany of scoring opportunities throughout the regular season. We doubt he’ll have the same opportunities on Sunday.

The postseason breeds more intense defense, and Darnold buckled badly against the same group twice the past 2 years. At the same time, while we expect Stafford, Puka Nacua and Davante Adams and others to get theirs, Seattle’s defense is too good to let the floodgates open the same way again. We’ll fade the market’s decision to place this total over the key number of 47.

Rams vs Seahawks prediction: Under 47.5 (-110) available at time of publishing. Playable to 47.

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Why Trust our NFL Picks

At the conclusion of the 2025 regular season, our team of NFL handicappers accumulated 296 wins (and 4 pushes) across sides and totals picks for every game, over those 18 weeks our record speaks for itself. Our expert NFL picks scored +78.1 units of profit throughout the regular season.

The first two rounds of the NFL playoffs are now in the rear view mirror. Through Wild Card Weekend and the Divisional Round we’re up an additional 11 winning NFL picks. You can see the full breakdown of our NFL picks record so far this season below:

NFL PickWinsPushLossesProfit (betting units)
Sides (Moneyline/ATS)1573120+61.8
Totals (Over / Under)1501129+31.4
Total3074249+93.2
2025 Regular Season + Playoffs

At Pickswise, every NFL pick is backed by years of betting experience, advanced data analysis, and a proven track record of success. Our team of handicappers studies line movement, injury reports, historical trends, and matchup stats to deliver informed recommendations — not guesses. We publish our results openly, update our predictions as new information emerges, and never hide behind vague analysis. Whether you’re looking for expert spreads, totals, props, or parlays, our mission is simple: give you honest, well-researched picks that stand up over time.

Free NFL Picks Explained

We firmly believe expert NFL picks should be free, so you’ll find our NFL picks today, and every day of the season, right here. We publish our free NFL picks for every game, at least a few days in advance of gameday, so you know who the experts are backing without missing out on the early value in the betting markets.

There’s almost an infinite way to bet on the NFL, from NFL picks against the spread, moneyline, over/under, NFL Parlays, and NFL Prop Bets, there is a bet type for every kind of football fan, so we provide NFL picks for every bet type. Some bettors like to specialize in a single particular type of NFL pick, while others like to have a diverse range and bet on anything they feel is a value pick.

Here at Pickswise, we have something for everyone. Our team of handicappers have a wealth of experience in making NFL picks across all these betting markets, leaving no stone unturned ahead of every game and every pick of the 2025 NFL season. If you’re looking for more information on NFL bet types, You can find our expert breakdown of each below.

NFL Picks Against the Spread

The most popular way to bet on the NFL is against the spread (ATS). With these wagers, you are not picking a simple winner or loser of a game. Instead, ATS betting is placing your money that Team A wins by a certain amount of points or that Team B will keep the game closer than oddsmakers expect, in other words, not lose by that same amount of points.

For Example

Philadelphia Eagles -7 – Philadelphia must win by 8 or more points to cover the spread.
Chicago Bears +7 – Chicago must win, or lose by 6 or fewer points to cover the spread.
Tie Scenario – If the game ended 27-20 to Philadelphia, the spread would be a tie, or a push and stakes would be returned.

  • The team that covers the spread wins the game outright around 80% of the time.
  • Road teams going into games as the favorite have covered the spread at 64% so far this season
  • Teams coming off a blowout loss (20+ points) tend to rebound against the spread, 57% of the time.

Free NFL Over / Under Picks

Another exciting way to still get in on the NFL action is with totals wagers. In these bets you don’t take a side, but whether the two teams will combine to score over or under the total number of points that the oddsmakers have set. Already since sports betting has been legalized we’ve seen many occasions where a hail mary, missed FG or XP has cost over or unders bettors, so be prepared to be in for the long haul with your totals bets. We preview every game of the NFL season, providing insight into the game as a whole alongside expert NFL picks so you can make informed NFL totals bets.

  • Overall, unders have proven the value pick in recent seasons, as defenses have caught up with scoring trending down since 2021
  • Unders bets have the edge in divisional games, landing 57% of the time. This trend gets stronger late in the season (week 13 onwards), especially in cold weather conditions.
  • Unders bets have landed on 58% of primetime games, as public betting tends to have a bias for the overs in these games.

Money Line NFL Picks

Ask any seasoned NFL bettor and they’ll tell you that ATS betting is exciting, but can also be frustrating. It is important to keep in mind that NFL teams only need to win by one, of course, they’d love to win by more, but they’ll change their schemes late on to secure a win, not to ensure they cover the spread. Your research could have given you the right side, but if they win by 6 instead of 7 your -6.5 bet is a loss. Therefore a lot of bettors like to keep it simple and take our expert NFL Money Line picks and bet on the NFL straight up.

  • Through the first 4 weeks of the 2025 season 6+ point favourites have been strong straight up, with a 16-2-1 record
  • Short underdogs (+1 to +3 on the spread) win outright 43% of the time, offering better value on the moneyline than the spread
  • Underdogs in lower scoring road games (less than 42 total points) win outright 39% of the time, but often at better prices than this record suggests.

2025-26 NFL Schedule 

This will be the 106th season in league history and is set to kick off with the NFL Kick-Off game on Thursday, September 4, hosted by the defending Super Bowl Champions Philadelphia Eagles, who take on the Dallas Cowboys. The regular season will come to a conclusion on January 4, 2026 with the NFL Playoffs scheduled to begin the following weekend on the 10th, 11th & 12th of January 2026. Super Bowl LX is scheduled for February 8, 2026, at Levi’s Stadium in San Francisco, California, the home of the 49ers.

NFL Playoff Picks

You can find our NFL picks for the 2026 Playoffs, right here, for free. Wildcard Weekend is scheduled to start January 10, upon the conclusion of week 18 our experts start to make their picks and predictions for the first round of the playoffs and after each round is concluded we prepare for the coming weekend, all the way up to the Super Bowl.

NFL Playoff Picks
NFL Wildcard Weekend Picks
NFL Divisional Round Picks
NFL Conference Championship Picks

NFL Expert Picks

Our NFL Football picks will be for every game throughout the regular season, with primetime games and the top matchups each week getting additional expert coverage which will extend to every playoff game. These NFL Football picks will come alongside analysis and the latest stats and trends to consider when betting. You can also find our NFL Best Bets for the top plays of the week and a confidence rating for our expert handicapper.

Looking for alternative football picks? then head to our College Football Picks page, where you’ll find the same level of expertise from the Pickswise handicapping team for all the headline games in the 2025 NCAA football season.

More Than Just NFL Football Picks

We also specialize in every major North American sport including the MLB, NBA, NHL, College Football, and College Basketball. Check out our site every day for some of the best bets in every major athletic contest and make sure to follow us on social media as well.

Andrew Wilsher, Managing Editor of Pickswise

Statistical Approach to NFL Picks

It’s our goal to provide you with the best NFL picks in the market. Our expert handicappers are all specially selected and assessed prior to joining the team to ensure their analysis. experience and results are among the best in the industry. Each capper will put hours of research into each pick and many have built statistical models to find their moneyline, spread and over/under picks so you don’t have to. Check out all of our cappers’ free NFL picks here every week of the season. 

Andrew Wilsher, Pickswise Managing Editor

NFL Picks FAQs

To bet against the spread in the NFL you are either betting the favorite to win by x number of points or the underdog to win, or lose by fewer than x points. For example the Chiefs -7 points or the Panthers +7 points.

The number of points is set by sportsbooks and is often referred to as the line

 

Pickswise is the best website to get free NFL picks against the spread. Our handicappers provide free insight, analysis, and data to back up which way they’re siding against the spread for every NFL game. So far this NFL season our experts have secured 86 winning NFL picks for a profit of 26 units

Pickswise is the best place to get free expert NFL picks. We have the best cappers and NFL picks on the market and you can get all of our NFL picks for free! every week.

Each pick is meticulously researched by an experienced NFL handicapper, using our own data, custom-built models, and analytical methods. Our profit this season is 26 units and rising, so don’t miss out on the best NFL picks this week.