NFL Picks

NFL picks for every game of the 2025-26 season. Our NFL expert picks are informed by key betting trends, statistical analysis and years of NFL betting experience. +27.2 units profit, from 238 winning NFL picks so far this season is the proof.

Our NFL picks this week include against the spread picks for every game in week 16, highlighted by an all-NFC West Thursday Night Football when the Rams take on the Seahawks. Sunday Night Football will see the Patriots travel to Baltimore to face the Ravens and on Monday Night Football it’s 49ers vs Colts.

The Playoffs are now just around the corner, and both qualification and seeding is still undecided for many teams. Bears vs Packers and Buccaneers vs Panthers are the divisional matchups with the most on the line, and therefore also not to be missed.

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5:00 PM ET
Tomorrow
FOX
Philadelphia Eagles
Washington Commanders
Eagles
Commanders
Point Spread Pick
WAS Commanders +7.0(-110)

One of the two games on Saturday’s NFL Week 16 slate comes in the NFC East, where the Eagles are set to take on the Commanders in the first of a pair of games over the final few weeks of the season. Philadelphia appeared to finally have its “get right” game a week ago, but it was against a Raiders team that is probably the worst outfit in football at the moment, so it’s hard to properly assess just how well the Eagles are playing at the moment. What we do know is that Philadelphia has largely struggled to consistently score for most of the season, and it’s actually the run game that has continued to underperform against expectations. This is the worst rush attack that the Eagles have had in years, and it’s certainly worth examining if Philadelphia will be able to continue winning without having a successful ground game. After all, it’s not as if Jalen Hurts is playing his best football at the moment, so the Eagles below average passing game shouldn’t be expected to have much success on the road in a divisional game.

On the other side, Washington is without Jayden Daniels for the remainder of the season, but Marcus Mariota has been effective as a backup quarterback when called upon this season. Just last week, the Commanders knocked off the Giants as short road underdogs, and the offense was surprisingly competent given the injuries that Washington has sustained to this point. With that in mind, even if the Commanders fall behind in this game, we can still count on Mariota and this offense to fight and stay within striking distance against an opponent that has struggled to win by margin all season long. I’ll take the full touchdown with the home team.

Eagles vs Commanders prediction: Commanders +7 available at time of publishing. Playable at that number. 

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Game Totals Pick
Under 45.0(-110)

Regardless of which team covers the spread on Saturday, my favorite bet on this game is on the under at the current number. The Eagles have been a money printer to the under this season, as games involving Philadelphia have gone under the total in 6 consecutive contests. There is something to be said for the fact that the Eagles defense is an elite unit, and Vic Fangio’s group should be able to bottle up the Washington offense on the ground, which should force Mariota and company into obvious passing situations on 3rd and long. Conversely, the Eagles offense has been largely unreliable in recent weeks, and it’s hard to trust Hurts and a stale offensive scheme to produce against a division rival on the road. Let’s go with the under while it’s still above the key number of 44.

Under 45 available at time of publishing. Playable to 44.5

8:20 PM ET
Tomorrow
FOX
Green Bay Packers
Chicago Bears
Packers
Bears
Money Line Pick
CHI Bears Win(+100)

One of the most consequential games on the NFL Week 16 slate comes in Chicago, where the Bears are going to take on the Green Bay Packers in a massive showdown in the NFC North. These teams just met two weeks ago in Green Bay, and the Packers were able to come out on top in a game that came down to the final possession. This time around, Chicago is in a much better position as a team, and I actually make the Bears a small favorite in this game given the key injuries that Green Bay has sustained in recent weeks. Ben Johnson’s group was just in a very difficult situational spot against the Browns a week ago, and this offense didn’t miss a beat against the stout Cleveland defense, as Chicago racked up 31 points and dominated the game from start to finish at home. Caleb Williams is playing the best football of his young NFL career at the moment, while the Bears defense has shown signs of improvement of late. Given the fact that Chicago came up just a few yards short of sending the previous meeting between these teams to overtime, it’s hard not to favor Williams and company to pick up a possible division-clinching win at home.

While Chicago has impressed me in recent weeks, the Packers are a team that I’ll be looking to fade in the immediate future, albeit through no fault of their own. Green Bay is still one of the best teams in the NFC, but the Packers’ hopes of winning a Super Bowl were essentially dashed a week ago when Micah Parsons went down with a torn ACL in a loss to the Broncos. The rest of the Green Bay defense is still very solid, but it’s hard to quantify just how much of a difference-maker Parsons is in a variety of areas. Elsewhere, the Packers might also be without top wide receiver Christian Watson in this game, and that doesn’t bode well for Jordan Love’s downfield passing efficiency against an opportunistic Bears secondary that has made a living on forcing turnovers this season. I’ll back the home ‘dog while I’m still getting plus-money in what should be a terrific game on Saturday.

Packers vs Bears prediction: Bears ML (+100) available at time of publishing. Playable to -110.

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Game Totals Pick
Over 46.5(-110)

Regardless of which team comes out on top on Saturday, the over is my preferred look on the total. While the Bears defense is improved, this is still a unit that has thrived on turnovers and has largely been unable to slow down competent opponents on a down-to-down basis this season. With that in mind, the Packers should be able to generate plenty of success in this game, even if Watson ends up sitting this one out. On the other side, the Bears offense has been absolutely rolling of late and Ben Johnson’s group is averaging nearly 27 points per game over the last four weeks. Let’s take the over in a matchup that could certainly produce some fireworks.

Over 46.5 available at time of publishing. Playable to 47.

Vote on who will win!

1:00 PM ET
Sun Dec 21
CBS
Buffalo Bills
Cleveland Browns
Bills
Browns
Point Spread PickBest Bet
BUF Bills -10(-125)

The Buffalo Bills will try to build on a massive win over their AFC East rival Patriots when they visit the Cleveland Browns in Week 16 of the NFL season on Sunday afternoon. My Bills vs. Browns pick is for the visitors to win and cover. If there is one thing we learned from Week 15, it’s that big spreads are often not big enough. There are simply some awful football teams this year; one such team is the Browns. They are 3-11 and have lost 3 games in a row, including by 18 points to San Francisco and by a 31-3 margin at Chicago this past Sunday. Cleveland even lost to lowly Tennessee during this stretch. Rookie QB Shedeur Sanders has been better than Dillon Gabriel — but that’s not saying much. Head coach Kevin Stefanski’s squad is 3rd-to-last in total offense, and only Las Vegas is averaging fewer points per game than Cleveland.
 
There are also a lot of really good teams this year, including the Bills. They may not be where they want since the Patriots still lead the AFC East, but Josh Allen and company are 10-4 and coming off a huge road win at New England to keep their division-title hopes alive. At the very least, the Bills are well on their way to another playoff berth. These are simply 2 squads going in very different directions. As such, this is one of those double-digit spreads that still isn’t big enough. The Browns are 0-3 ATS in their last 3 overall and 2-5 ATS in the last 7 head-to-head meetings.

Bills vs Browns predictions: Buffalo Bills -10 (-125) available at time of publishing. Playable to -12.5.

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Game Totals Pick
Over 41.5(-108)

The Browns really have just one bright spot in 2025, which is obviously defensive end Myles Garrett. Of course, Allen is one of the best quarterbacks in the NFL and is extremely mobile — he is not easy to bring down in the backfield. Even against a respectable Cleveland defense, I think Allen and the entire Buffalo offense are in line for a productive outing. As such, my Bills vs. Browns pick is Over 41.5.

The Bills just torched a stout Patriots defense for 35 points, with all 35 coming in the final 3 quarters — including 28 in the second half — after New England once led 21-0. To say that Buffalo’s offense has a ton of momentum right now would be a gross understatement. On the other side of the ball, Sanders is at least showing some signs of promise for the Browns. They have scored at least 24 points in 2 of Sanders’ 4 NFL starts. In general, Cleveland is a run-first team, which is good news since Buffalo is the third-worst rushing defense in the league. It’s a lean toward the over for me.

Bills vs Browns prediction: Over 41.5 (-108) available at time of publishing. Playable to 42.

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1:00 PM ET
Sun Dec 21
CBS
Cincinnati Bengals
Miami Dolphins
Bengals
Dolphins
Point Spread Pick
CIN Bengals -4.0(-110)

The Cincinnati Bengals head to Miami this Sunday for a matchup against the Dolphins, and both teams are already counting down the days until next season. Cincinnati had its season derailed when QB Joe Burrow exited its Week 2 game with a turf toe injury, but things haven’t been much better since he returned. After a big win over the Baltimore Ravens on Thanksgiving night, Cincinnati has dropped two in a row to the Bills and Ravens, and the Bengals weren’t even competitive last week against Baltimore, falling 24-0. Luckily for them, they’ll be going up against a 6-8 Dolphins team that just turned to rookie QB Quinn Ewers after head coach Mike McDaniels announced the benching of Tua Tagovailoa. Both teams are mathematically eliminated from the playoffs, but I expect the Bengals will be the team with a stronger response after last week’s embarrassing defeat.

The ‘Phins started turning heads during their 4-game win streak, but 3 of those wins came against the Commanders, Saints and Jets. They showed little life in last week’s loss to the Pittsburgh Steelers after falling behind 28-3, but managed to score 2 garbage-time touchdowns. Additionally, the Bengals being shut out last week actually gives them a boost based on historical trends. Since 2015, teams that were shut out in the previous week are 35-17-3 against the spread in their next game and a perfect 5-0 ATS this season. This marked the Bengals’ first shutout with Burrow as the QB, and there’s no doubt in my mind that he’ll want to bounce back in a big way.Finally, McDaniel and the Dolphins have been awful on short rest; they’re just 3-10 since he took over, losing by 8.2 PPG. Although the Bengals have struggled this year, they’ll be up against a rookie QB in his first start after a disappointing loss; give me Cincinnati to win big on Sunday.

Bengals vs Dolphins prediction: Cincinnati Bengals -4 (-110) available at the time of publishing, playable down to -5.5.

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Game Totals Pick
Over 47.5(-110)

I expect Cincinnati to win big this weekend, and they’re going to need to do most of the scoring to push this one over. However, I do think Miami can still put up points, even with a rookie QB, because of how bad this Bengals defense has been all season. Cincinnati allows 31.2 PPG (last in the NFL), and although they’ve had to face Lamar Jackson twice, Josh Allen and Drake Maye over the last 4 weeks, they’ve allowed plenty of points to quarterbacks that are a tier below those three. They gave up 39 points to the Justin Fields-led Jets in Week 8, 48 to Carson Wentz and the Vikings in Week 3, and 65 over 2 games against a Steelers team that averages just 24 PPG. I expect Miami to rely on RB De’Von Achane even more with Ewers under center, especially because the Bengals allow 5.3 yards per carry (30th in the NFL). 

On the flip side, I’m not high on this Miami defense. The Dolphins give up up 6.8 yards per pass attempt (20th in the NFL) and will now face a Bengals offense with extra motivation after being shut out. Additionally, Cincinnati scored 32 and 34 before last week’s shutout, and it looks like they will get WR Tee Higgins back from a concussion. Meanwhile, Miami could miss some key pieces on defense. S Minkah Fitzpatrick is doubtful, and leading tackle LB Jordyn Brooks is questionable and didn’t practice on Wednesday. This defense is beat up and is playing on short rest; I can’t see them suddenly turning things around. All in all, I expect this game to end in the 35-17 range, which should be enough to cash the over.

Bengals vs Dolphins prediction: Over 47.5 (-110) available at the time of publishing, playable up to 48.5.

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1:00 PM ET
Sun Dec 21
FOX
Los Angeles Chargers
Dallas Cowboys
Chargers
Cowboys
Point Spread Pick
LA Chargers +2.5(-112)

The Cowboys (6-7-1) were on the verge of salvaging their season with a three-game winning streak to finish off November, capped off by a home underdog victory over the Chiefs. However, Dallas allowed 77 points in the past two losses to Detroit and Minnesota to fall below .500 and three games behind Philadelphia in the win column in the NFC East. The Cowboys try to rebound off a 34-26 home defeat to the Vikings last Sunday night with a visit from the red-hot Chargers on Sunday.

Los Angeles (10-4) seeks its fourth straight win and sixth victory in the past seven tries. The Chargers are back on the road after pulling off the season sweep of the Chiefs, 16-13 as six-point underdogs. Not only did L.A. knock Kansas City out of playoff contention, but the Lightning Bolts are part of a five-team class in the AFC with at least 10 wins. It marked the fourth victory for Jim Harbaugh’s club by 3 or fewer points, while allowing fewer than 19 points for the third consecutive week.

This is the home finale for the Cowboys, who wrap up the regular season on the road against the Commanders and Giants. Dallas has struggled in the role of a home favorite, going 1-3 against the spread, compared to a perfect 3-0 ATS mark as a home underdog. The Chargers have covered and won in all three opportunities as an underdog this season, while not giving up more than 21 points in any of those games. The Cowboys scored two early TDs against Minnesota, but didn’t reach the end zone in nearly the final three quarters. This pick isn’t about riding the trends, but Dallas proved it has struggled as a favorite, while L.A. has thrived in the ‘dog role.

Los Angeles Chargers vs Dallas Cowboys prediction: Chargers +2.5 (-112) available at time of publishing. Playable to +2.

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Game Totals Pick
Under 49.5(-105)
1:00 PM ET
Sun Dec 21
FOX
Tampa Bay Buccaneers
Carolina Panthers
Buccaneers
Panthers
Point Spread PickBest Bet
TB Buccaneers -3.0(-108)

Tampa Bay and Carolina enter Sunday’s critical NFC South matchup tied atop the division at 7-7. The Buccaneers have slumped down the stretch, dropping five of their last six games with the lone victory coming by three against the Cardinals in Week 13. Tampa Bay visits Bank of America Stadium against a Carolina squad that lost on field goal in the final seconds of last Sunday’s 20-17 defeat at New Orleans.

 

The Panthers are 5-1 off a loss this season, as Carolina led New Orleans, 17-7 late in the third quarter before the Saints scored the final 13 points of the game.  In the underdog role, Carolina has posted a solid 8-3 ATS mark, including a 4-1 ATS record at home. In their last home game, the Panthers stunned the Rams as 10.5-point underdogs, 31-28 in their highest-scoring game of the season. Carolina has scored 61 points in its last two games off a loss, but has also allowed 55 points in those victories.

Tampa Bay needs to get on track fast as the Buccaneers control their destiny with two meetings against the Panthers over the final three games. The Bucs shouldn’t be in this position, as they lost to two teams at home that are not headed to the playoffs – the Saints and Falcons. In fact, the Bucs are 0-6 ATS in the last six games, but have not been listed as a road favorite in this stretch. Tampa Bay is 2-0 SU/ATS in two opportunities when laying points away from Raymond James Stadium, winning at Atlanta and New Orleans. In the past 10 matchups, the Buccaneers are 9-1 against the Panthers and QB Baker Mayfield has not lost to Carolina since taking over in 2023. The trends point towards Carolina, but this looks like the get-right game for Tampa Bay to save its season, so we’ll lay the points with the Bucs.

Tampa Bay Buccaneers vs Carolina Panthers prediction: Bucs -3 (-108) available at time of publishing. Playable at that number.

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Game Totals Pick
Over 45.5(-110)

Neither of these division rivals own overwhelming numbers in the totals department. The Bucs are 8-6 to the Over, while the Panthers are 7-7 to the Over. Carolina has been inconsistent in this category due its erratic play this season, alternating Overs and Unders in the last five games, coming off the Under in last Sunday’s 20-17 walk-off loss at New Orleans on a 41.5 total. Tampa Bay is off consecutive Overs in the past two home defeats to New Orleans and Atlanta, while giving up at least 27 points at home for the fourth time last Thursday against the Falcons.

The last two road defensive outings for the Buccaneers have been ugly, yielding 34 points to the Rams and 44 points to the Bills in a pair of losses. In both games as a road favorite, Tampa Bay finished Under the total in the Week 1 comeback victory at Atlanta and the 23-3 rout of New Orleans in Week 8. Tampa Bay and Carolina see each other twice in the final three weeks of the season with the division crown on the line, as both matchups in 2024 sailed Over the total. The Bucs rank 25th in the NFL in yards allowed per game (348.2) and are allowing 25.3 ppg.

Carolina’s roller-coaster season is defined by this number: the Panthers are averaging 18.9 ppg although they have scored at least 30 points in four games. They have also been held to 13 or fewer points four times, so you wonder which Carolina offense shows up on Sunday in this critical showdown. We’ll buy into the trend that the Panthers will score points here against this struggling Tampa Bay defense, while the Bucs can put up points, as well, in what should be an exciting game with first place on the line in the NFC South.

Tampa Bay Buccaneers vs Carolina Panthers: Over 45.5 (-110) available at time of publishing. Playable to 46.5.

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4:05 PM ET
Sun Dec 21
FOX
Atlanta Falcons
Arizona Cardinals
Falcons
Cardinals
Point Spread Pick
ATL Falcons -2.5(-120)

The Arizona Cardinals have lost 11 of their last 12 games heading into a home date with the Atlanta Falcons in Week 16 of the NFL season on Sunday afternoon. Arizona probably doesn’t have the talent or the motivation level to turn things around at this point in the season, so my Falcons vs Cardinals pick is for the visitors to win and cover. Arizona’s defense is horrible. It has allowed 45 and 40 points the last 2 weeks and has given up 40 or more points a ridiculous 4 times during its current 6-game losing streak.

Much unlike the Cardinals, the Falcons are still putting forth a solid effort despite having long since been eliminated from playoff contention. Atlanta has won 2 games in a row, most recently upsetting the NFC South-leading Bucs in Week 15 after trailing by 2 touchdowns in the fourth quarter. That was on Thursday Night Football, so head coach Raheem Morris’ squad is effectively playing on a mini-bye week of rest. This is a great spot for a suddenly confident Falcons team against a Cardinals club that is among the worst in the entire NFL.

Atlanta Falcons vs Arizona Cardinals prediction: Falcons -2.5 (-120) available at time of publishing. Playable to -3.

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Game Totals Pick
Under 48.5(-110)

This is a quarterback matchup between Atlanta’s Kirk Cousins and Arizona’s Jacoby Brissett. Although both veterans clearly have at least a little bit left in the tank, neither one inspires a ton of confidence. You could maybe say that each one is solid, but they don’t provide any dynamic element to their respective offenses. That is part of the reason why my Falcons vs Cardinals pick is Under 48.5.

There is no denying that Arizona’s defense stinks, but can Atlanta take full advantage? Maybe not. WR1 Drake London is questionable with a knee injury and is trending toward missing a fourth consecutive contest. Tight end Kyle Pitts, who went crazy to the tune of 166 yards and 3 touchdowns last Thursday night, is questionable with a knee issue of his own. Fortunately for the Falcons, their defense has overachieved in 2025. The franchise’s previously nonexistent pass rush is second in the NFL in sacks, led by rookie first-round draft pick James Pearce Jr. This will not be an easy day at the office for Brissett, and the Cardinals don’t have the running game to capitalize on a vulnerable Atlanta run defense.

Atlanta Falcons vs Arizona Cardinals prediction: Under 48.5 (-110) available at time of publishing. Playable 48.

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8:20 PM ET
Sun Dec 21
NBC
New England Patriots
Baltimore Ravens
Patriots
Ravens
Point Spread PickBest Bet
NE Patriots +3.0(-115)

For the first time all season, the Baltimore Ravens finally had an easy win in week 15. Of course, Cincinnati seemed deflated from the very start of last week’s game, and a Joe Burrow lead offense was out of its rhythm, failing to score a single point. The ravens deserve credit all around, they showed up and got the job done and they must-win situation, but it still doesn’t improve that their struggles have ceased. We also can’t dismiss that Baltimore still ranks a lowly 20th in total offensive EPA metrics, and they’re not much better on defense either (16th). Their secondary is even more concerning, ranked 19th in defensive EPA per pass and permitting 233.3 passing yards per game (26th). Even worse, only the 49ers sack the quarterback less (Baltimore ranks 31st, taking down the quarterback on only 4.14% of plays). We hate that for their matchup on Sunday night.

There is no reasonable evidence that suggests the Ravens are a better team than the Patriots entering Week 16. Baltimore’s edge is that they’re at home and that they have more experience in big-time matchups like this, a cyclical playoff participant under the era of John Harbaugh and Lamar Jackson. But when it comes to this season, the Patriots are the better team in every category. Offensively they rank 6th in total offensive EPA and 12th in total defensive EPA, not to mention they’re coming off a 10-game winning streak, which was broken in Week 15.

Speaking of Week 15, we’re not concerned about the Patriots because of one flawed half. Many teams fall victim to the magic of Josh Allen, who engineered yet another second half comeback last Sunday. New England showed its youth and inexperience last weekend, but otherwise they’ve been one of the most consistent programs in the NFL. In fact, only the Seahawks and Rams, two other 11-3 outfits, have a better point-differential than Mike Vrabel’s team (+7.6). 

Especially since they’re coming off a loss, there’s simply no way we could bet on the Ravens here. Too many times we’ve seen their defense capitulate, and even in an easy win last week, their offense was rather pedestrian (317 total yards, 15 first downs). Meanwhile, the Patriots have been a well-oiled machine and one of the best ATS teams all season (8-5-1, 61.5%). If we’re getting a field goal with the visitors, we’re taking it.

Patriots vs Ravens: Patriots +3 (-110) available at time of publishing. Playable at that number.

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Game Totals Pick
Over 48.0(-110)

This total is curiously high. Maybe part of that is because Baltimore will be unseasonably mild and calm on Sunday night, forecasted to be in the mid-40s — a perfect night for football. Perhaps it will become a perfect night for scoring, too. The market is certainly sending a signal by posting this above 47, a prime key number in totals.

Matchup wise, it makes sense. New England’s defense has mostly been very good this season — but it is also coming off a contest in which it got exposed by a dynamic quarterback. Arguably no NFL quarterback is as dynamic as Lamar Jackson, a true outlier athlete with a legitimate rifle of an arm to boot — very Josh Allen-like. The market is likely responding to the fact that New England’s schedule has featured very few top-tier offenses. In fact, according to EPA metrics, they Pats have only clashed with two top-15 offenses this season (BUF, PIT). Despite Baltimore’s transgressions this season, it can overwhelm any defense when functioning at a high level. 

The Patriots’ offense needs no introduction at this point, nor does the missteps of the Ravens’ defense. Defensively, Week 15 was easily Baltimore’s most impressive showing all season — blanking the Bengals and holding Joe Burrow and company to only 298 total yards. Despite holding the ball for nearly two-thirds of the game (39:19), Cincinnati went 3-for-15 on third-down conversions, too. Still, we haven’t seen that version of the Ravens’ defense for any consistent stretch all year — it’s a group that permits 344.4 yards per game (23rd). Both offenses are in a good spot and I trust both teams to rely on their production in this huge Sunday night game. I can only look at the over.

Patriots vs Ravens prediction: Over 48 (-110) available at time of publishing. Playable at that number.

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Why Trust our NFL Picks

Through week 15 of the 2025 season our team of NFL handicappers have made against the spread and totals picks for every game. with 238 wins (and 3 pushes) our record speaks for itself. Our expert NFL picks have scored +27.2 units of profit so far this season.

NFL PickWinsPushLossesProfit (betting units)
Sides (Moneyline/ATS)121299+23.4
Totals (Over / Under)1171103+3.8
Total2383202+27.2

At Pickswise, every NFL pick is backed by years of betting experience, advanced data analysis, and a proven track record of success. Our team of handicappers studies line movement, injury reports, historical trends, and matchup stats to deliver informed recommendations — not guesses. We publish our results openly, update our predictions as new information emerges, and never hide behind vague analysis. Whether you’re looking for expert spreads, totals, props, or parlays, our mission is simple: give you honest, well-researched picks that stand up over time.

Free NFL Picks Explained

We firmly believe expert NFL picks should be free, so you’ll find our NFL picks today, and every day of the season, right here. We publish our free NFL picks for every game, at least a few days in advance of gameday, so you know who the experts are backing without missing out on the early value in the betting markets.

There’s almost an infinite way to bet on the NFL, from NFL picks against the spread, moneyline, over/under, NFL Parlays, and NFL Prop Bets, there is a bet type for every kind of football fan, so we provide NFL picks for every bet type. Some bettors like to specialize in a single particular type of NFL pick, while others like to have a diverse range and bet on anything they feel is a value pick.

Here at Pickswise, we have something for everyone. Our team of handicappers have a wealth of experience in making NFL picks across all these betting markets, leaving no stone unturned ahead of every game and every pick of the 2025 NFL season. If you’re looking for more information on NFL bet types, You can find our expert breakdown of each below.

NFL Picks Against the Spread

The most popular way to bet on the NFL is against the spread (ATS). With these wagers, you are not picking a simple winner or loser of a game. Instead, ATS betting is placing your money that Team A wins by a certain amount of points or that Team B will keep the game closer than oddsmakers expect, in other words, not lose by that same amount of points.

For Example

Philadelphia Eagles -7 – Philadelphia must win by 8 or more points to cover the spread.
Chicago Bears +7 – Chicago must win, or lose by 6 or fewer points to cover the spread.
Tie Scenario – If the game ended 27-20 to Philadelphia, the spread would be a tie, or a push and stakes would be returned.

  • The team that covers the spread wins the game outright around 80% of the time.
  • Road teams going into games as the favorite have covered the spread at 64% so far this season
  • Teams coming off a blowout loss (20+ points) tend to rebound against the spread, 57% of the time.

Free NFL Over / Under Picks

Another exciting way to still get in on the NFL action is with totals wagers. In these bets you don’t take a side, but whether the two teams will combine to score over or under the total number of points that the oddsmakers have set. Already since sports betting has been legalized we’ve seen many occasions where a hail mary, missed FG or XP has cost over or unders bettors, so be prepared to be in for the long haul with your totals bets. We preview every game of the NFL season, providing insight into the game as a whole alongside expert NFL picks so you can make informed NFL totals bets.

  • Overall, unders have proven the value pick in recent seasons, as defenses have caught up with scoring trending down since 2021
  • Unders bets have the edge in divisional games, landing 57% of the time. This trend gets stronger late in the season (week 13 onwards), especially in cold weather conditions.
  • Unders bets have landed on 58% of primetime games, as public betting tends to have a bias for the overs in these games.

Money Line NFL Picks

Ask any seasoned NFL bettor and they’ll tell you that ATS betting is exciting, but can also be frustrating. It is important to keep in mind that NFL teams only need to win by one, of course, they’d love to win by more, but they’ll change their schemes late on to secure a win, not to ensure they cover the spread. Your research could have given you the right side, but if they win by 6 instead of 7 your -6.5 bet is a loss. Therefore a lot of bettors like to keep it simple and take our expert NFL Money Line picks and bet on the NFL straight up.

  • Through the first 4 weeks of the 2025 season 6+ point favourites have been strong straight up, with a 16-2-1 record
  • Short underdogs (+1 to +3 on the spread) win outright 43% of the time, offering better value on the moneyline than the spread
  • Underdogs in lower scoring road games (less than 42 total points) win outright 39% of the time, but often at better prices than this record suggests.

2025-26 NFL Schedule 

This will be the 106th season in league history and is set to kick off with the NFL Kick-Off game on Thursday, September 4, hosted by the defending Super Bowl Champions Philadelphia Eagles, who take on the Dallas Cowboys. The regular season will come to a conclusion on January 4, 2026 with the NFL Playoffs scheduled to begin the following weekend on the 10th, 11th & 12th of January 2026. Super Bowl LX is scheduled for February 8, 2026, at Levi’s Stadium in San Francisco, California, the home of the 49ers.

NFL Playoff Picks

You can find our NFL picks for the 2026 Playoffs, right here, for free. Wildcard Weekend is scheduled to start January 10, upon the conclusion of week 18 our experts start to make their picks and predictions for the first round of the playoffs and after each round is concluded we prepare for the coming weekend, all the way up to the Super Bowl.

NFL Playoff Picks
NFL Wildcard Weekend Picks
NFL Divisional Round Picks
NFL Conference Championship Picks

NFL Expert Picks

Our NFL Football picks will be for every game throughout the regular season, with primetime games and the top matchups each week getting additional expert coverage which will extend to every playoff game. These NFL Football picks will come alongside analysis and the latest stats and trends to consider when betting. You can also find our NFL Best Bets for the top plays of the week and a confidence rating for our expert handicapper.

Looking for alternative football picks? then head to our College Football Picks page, where you’ll find the same level of expertise from the Pickswise handicapping team for all the headline games in the 2025 NCAA football season.

More Than Just NFL Football Picks

We also specialize in every major North American sport including the MLB, NBA, NHL, College Football, and College Basketball. Check out our site every day for some of the best bets in every major athletic contest and make sure to follow us on social media as well.

Andrew Wilsher, Managing Editor of Pickswise

Statistical Approach to NFL Picks

It’s our goal to provide you with the best NFL picks in the market. Our expert handicappers are all specially selected and assessed prior to joining the team to ensure their analysis. experience and results are among the best in the industry. Each capper will put hours of research into each pick and many have built statistical models to find their moneyline, spread and over/under picks so you don’t have to. Check out all of our cappers’ free NFL picks here every week of the season. 

Andrew Wilsher, Pickswise Managing Editor

NFL Picks FAQs

To bet against the spread in the NFL you are either betting the favorite to win by x number of points or the underdog to win, or lose by fewer than x points. For example the Chiefs -7 points or the Panthers +7 points.

The number of points is set by sportsbooks and is often referred to as the line

 

Pickswise is the best website to get free NFL picks against the spread. Our handicappers provide free insight, analysis, and data to back up which way they’re siding against the spread for every NFL game. So far this NFL season our experts have secured 86 winning NFL picks for a profit of 26 units

Pickswise is the best place to get free expert NFL picks. We have the best cappers and NFL picks on the market and you can get all of our NFL picks for free! every week.

Each pick is meticulously researched by an experienced NFL handicapper, using our own data, custom-built models, and analytical methods. Our profit this season is 26 units and rising, so don’t miss out on the best NFL picks this week.